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Ca2+ control of actin-myosin interaction

Ca2+-Steuerung der Aktin-Myosin-Interaktion

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Experimental Cardiac Hypertrophy and Heart Failure

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Summary

Some aspects of the Ca2+-regulation of actin-myosin interaction are discussed. Emphasis is placed on Ca2+-induced conformational changes in the Ca2+-binding subunit of troponin that leads to deinhibition of the actin-myosin interactions.

The preparation of this manuscript and work in the author’s laboratory is supported by grants from NIH (HL-5949), the National Science Foundation and the Muscular Dystrophy Associations of America, Inc.

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Authors and Affiliations

  1. Dept. of Muscle Research, Boston Biomedical Research Institute, Boston, Massachusetts, 02114, USA

    Dr. J. Gergely

  2. Department of Neurology, General Hospital, Massachusetts, USA

    Dr. J. Gergely

  3. Department of Biological Chemistry, Harvard Medical School, Boston, Massachusetts, USA

    Dr. J. Gergely

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  1. Dr. J. Gergely
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Editors and Affiliations

  1. Tübingen, Germany

    Ruthard Jacob (Prof. Dr.) (Prof. Dr.)

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© 1980 Springer-Verlag Berlin Heidelberg

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Gergely, J. (1980). Ca2+ control of actin-myosin interaction. In: Jacob, R. (eds) Experimental Cardiac Hypertrophy and Heart Failure. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-41468-2_3

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  • DOI: https://doi.org/10.1007/978-3-662-41468-2_3

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-7985-0577-3

  • Online ISBN: 978-3-662-41468-2

  • eBook Packages: Springer Book Archive

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