Abstract
A single dose of 500 mg thiamphenicol (TAP) was given to 30 women at various times prior to interruption of pregnancy for social and/or medical reasons during the first trimester (curettage, hysterotomy, or prostaglandin induction). Concentrations of TAP were then determined in maternal serum, placental, and fetal tissues by a gas chromatographic method using electron capture detection. Similar, but sometimes significantly higher, concentrations of TAP were found in placental and fetal tissues as compared to maternal serum (data expressed as μg/ml or μg/g).
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© 1978 Springer-Verlag Berlin Heidelberg
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Nau, H., Welsch, F., Egger, H. (1978). Diaplacental Transfer and Fetal Distribution of Thiamphenicol in Early Human Pregnancy. In: Deutsche Pharmakologische Gesellschaft. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-39532-5_59
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DOI: https://doi.org/10.1007/978-3-662-39532-5_59
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-38666-8
Online ISBN: 978-3-662-39532-5
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