Abstract
N′-Methyl-N′-β-chloroethylhydrazones show cytostatic, immune suppressive and immune stimulative activities according to their dosage and way of application. These hydrazones cause a strong inhibition of the uptake of nucleosides into Ehrlich-ascites-carcinoma cells (EAC), but no interference with DNA or RNA polymerizing systems could be observed. Therefore, an attack on the cell membrane was supposed.
This is a preview of subscription content, log in via an institution.
Buying options
Tax calculation will be finalised at checkout
Purchases are for personal use only
Learn about institutional subscriptionsAuthor information
Authors and Affiliations
Rights and permissions
Copyright information
© 1978 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Braun, R., Dittmar, W., Gassel, WD. (1978). Investigations on the Membrane Activity of Cytostatic Methyl Hydrazones. In: Deutsche Pharmakologische Gesellschaft. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-39532-5_24
Download citation
DOI: https://doi.org/10.1007/978-3-662-39532-5_24
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-38666-8
Online ISBN: 978-3-662-39532-5
eBook Packages: Springer Book Archive