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Skeletal Muscle Weakness and Fatigue in Old Age: Underlying Mechanisms

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Special Focus on the Biology of Aging

Abstract

Although muscle atrophy, decline in muscle strength, and physical frailty are widely accepted as inevitable concomitants of old age (Kaldor & DiBattista, 1979), the underlying causes are not known. Consequently, the degree to which these changes are preventable and treatable is unclear. Understanding the mechanisms involved may assist in the interpretation of the causes of instability and falls that are common for elderly people.

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Authors and Affiliations

  1. University of Michigan, USA

    John A. Faulkner, Susan V. Brooks & Eileen Zerba

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  1. John A. Faulkner
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  2. Susan V. Brooks
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  3. Eileen Zerba
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Editors and Affiliations

  1. Center for Gerontological Research, Department of Physiology and Biochemistry, Medical College of Pennsylvania, Philadelphia, PA, USA

    Vincent J. Cristofalo Ph.D.

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Faulkner, J.A., Brooks, S.V., Zerba, E. (1991). Skeletal Muscle Weakness and Fatigue in Old Age: Underlying Mechanisms. In: Cristofalo, V.J., Lawton, M.P. (eds) Special Focus on the Biology of Aging. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-38445-9_9

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  • DOI: https://doi.org/10.1007/978-3-662-38445-9_9

  • Publisher Name: Springer, Berlin, Heidelberg

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