Skip to main content
SpringerLink
Log in

Variotin

  • Chapter
Biosynthesis

Part of the book series: Antibiotics ((ANTIBIOTICS))

Abstract

Variotin, an antifungal antibiotic, is produced by Paecilomyces varioti Bainer var. antibioticus and was isolated by Takeuchi et al. (1959). It does not inhibit bacteria and some fungi at 160 μg/m1 but does inhibit a number of fungi pathogenic to man such as Blastomyces dermatitidis, Trichophyton rubrum and Microsporum audouini at 0.25 μg/ml or less. It is used topically for the treatment of human dermatomycosis.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Abe, S., S. Takeuchi, and H. Yonehara: Studies on variotin, a new antifungal antibiotic. II. Taxonomical studies on variotin-producing strain. J. Antibiotics (Japan), Ser. A 12, 201 (1959).

    CAS  Google Scholar 

  • Takeuchi, S., H. Yonehara, and H. Umezawa: Studies on variotin, a new antifungal antibiotic. I. Preparation and properties of variotin. J. Antibiotics (Japan), Ser. A 12, 195 (1959).

    CAS  Google Scholar 

  • Takeuchi, S., and H. Yonehara: Studies on variotin, a new antifungal antibiotic.

    Google Scholar 

  • Iii. Chemical structure of variotin. J. Antibiotics (Japan), Ser. A 14, 44 (1961).

    Google Scholar 

  • Takeuchi, S., and H. Yonehara: Crystallized variotin and its revised chemical structure. J. Antibiotics (Japan), Ser. A 17, 267 (1964).

    CAS  Google Scholar 

  • Tanaka, N., and H. Umezawa: Biogenesis of variotin. I. Incorporation of CH3 14CO2H and 14CH3CO2H into variotin. J. Gen. Appl. Microbiol. 8, 149 (1962).

    Article  CAS  Google Scholar 

  • Tanaka, N., and H. Umezawa: Biogenesis of variotin. II. Incorporation of 14CH3SCH2–CH2CH(NH2)CO2H into variotin. J. Gen. Appl. Microbiol. 8, 160 (1962).

    Article  CAS  Google Scholar 

  • Tanaka, N., K. Sashikata, and H. Umezawa: Biogenesis of variotin. Iii. Incorporation of 14C-glutamic acid into variotin. J. Gen. Appl. Microbiol. 8, 192 (1962).

    Article  CAS  Google Scholar 

Download references

Authors
  1. Nobuo Tanaka
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. Department of Plant Pathology, University of Illinois, Urbana, Illinois, USA

    David Gottlieb (Professor of Plant Pathology) (Professor of Plant Pathology)

  2. University of Illinois, Urbana, Illinois, USA

    Paul D. Shaw (Associate Professor of Biochemistry) (Associate Professor of Biochemistry)

Rights and permissions

Reprints and permissions

Copyright information

© 1967 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

Tanaka, N. (1967). Variotin. In: Gottlieb, D., Shaw, P.D. (eds) Biosynthesis. Antibiotics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-38441-1_17

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-38441-1_17

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-37650-8

  • Online ISBN: 978-3-662-38441-1

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation