Antibiotics pp 415-426 | Cite as


  • Laura Frontali
  • Giorgio Tecce


Rifamycins1 are a group of closely related antibiotics produced by a Streptomyces strain first isolated in “Lepetit Research Laboratories” (Milan, Italy) from a soil sample collected near St. Raphael (France). The strain was cultured in shakeflasks and the fermentations broths showed high activity against grampositive bacteria and Mycobacterium tuberculosis (Sensi et al., 1959). A limited activity against gramnegative bacteria was also present. A detailed description of this strain was reported by Margalith and Beretta (1960); its cultural and biochemical characteritics led these Authors to conclude that this strain constitutes a new species which was named Streptomyces mediterranei.


Bacillus Subtilis Neisseria Gonorrhoeae Magnesium Acetate Subtilis Cell Brucella Melitensis 
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© Springer-Verlag Berlin Heidelberg 1967

Authors and Affiliations

  • Laura Frontali
  • Giorgio Tecce

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