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Antibiotics pp 153-155 | Cite as

Albomycin

  • B. K. Bhuyan

Abstract

Albomycin is a cyclic iron-containing peptide produced by Actinomyces subtropicus (Gause and Brazhnikova, 1951). Most of the chemical and biological properties of albomycin have been reviewed by Gause (1955). Some of the properties of the antibiotic are listed in Table 1. Albomycin inhibits the growth of gram-positive cocci, chiefly pneumococcus and staphylococcus, and is also effective against several gram-negative bacteria, e.g., the coli-dysentery group. In view of its marked activity, particularly against penicillin resistant staphylococcus, and lack of toxicity, albomycin has undergone clinical trial in the U.S.S.R. (Gause, 1955). In clinical practice albomycin is used mainly in the treatment of infections caused by pathogenic cocci and in various septic conditions caused by penicillin resistant cocci. Albomycin binds partially and reversibly to serum. However, the albomycin-serum complex possesses chemotherapeutic activity, indicating dissociation of the complex in vivo (Gause, 1955).

Keywords

Marked Activity Cyclic Peptide Nucleic Acid Metabolism Septic Condition Endogenous Respiration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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Copyright information

© Springer-Verlag Berlin Heidelberg 1967

Authors and Affiliations

  • B. K. Bhuyan

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