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Verhandlungen der Schweizerischen Gesellschaft für Gynäkologie und Geburtshilfe pp 259–271Cite as

Transplantation hépatique et grossesse: Perspectives en 1994

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Part of the book series: Archives of Gynecology and Obstetrics ((AGYO))

Résumé

Les auteurs rapportent le cas d’une grossesse chez une patiente IIIG IP de 24 ans ayant subi 2 ans auparavant une transplantation hépatique pour échino-cocccose alvéolaire. La grossesse et l’accouchement se sont déroulés sans problème obstétrical ni hépatique. La grossesse semble peu influencer la transplantation hépatique et les rejets sont rares. Les principales complications maternelles sont l’hypertension artérielle, la gestose, l’anémie et l’hyperbilirubinémie. Les complications foetales sont principalement la prématurité et le retard de croissance intra-utérin. Le mode d’accouchement dépend des complications obstétricales rencontrées. L’utilisation de Ciclosporine ne présente pas de problème, mais reste discutée durant l’allaitement. La grossesse après transplantation hépatique est possible dans un délai de 9–12 mois, mais nécessite une surveillance multidisciplinaire stricte. Toute patiente transplantée en âge de procréer et qui ne désire pas de grossesse nécessite une contraception et la préférence sera accordée aux méthodes barrières.

Summary

The authors report a caseof pregnancy in a 24-year-old, gravida-3, para-1 patient who had previously undergone liver transplantation for alveolar echinococcosis. Pregnancy and delivery were uneventful with no obstetrical or liver complications. Pregnancy seems to have little effect on liver transplants and rejection is seldom observed. Primary maternal complications are hypertension, preeclampsia, anemia and hyperbilirubinemia. Primary fetal complications include premature delivery and growth retardation. The mode of delivery depends on the obstetrical situation. Cyclosporin may be used during pregnancy. The risk of breastfeeding has not been clearly established. Pregnancy after liver transplantation is possible after 9 to 12 months but requires strict multidisciplinary surveillance. Barrier methods remain the preferred method of contraception for liver transplant patients.

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Authors and Affiliations

  1. Département de Gynécologie-Obstétrique, CHUV, CH-1011, Lausanne, Schwitzerland

    Ph. Sauthier, P. Hohlfeld & H. Bossart

  2. Département de Chirurgie, CHUV, CH-1011, Lausanne, Schwitzerland

    F. Mosimann

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  1. Ph. Sauthier
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© 1994 Springer-Verlag Berlin Heidelberg

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Sauthier, P., Hohlfeld, P., Mosimann, F., Bossart, H. (1994). Transplantation hépatique et grossesse: Perspectives en 1994. In: Verhandlungen der Schweizerischen Gesellschaft für Gynäkologie und Geburtshilfe. Archives of Gynecology and Obstetrics. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-37814-4_5

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  • DOI: https://doi.org/10.1007/978-3-662-37814-4_5

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