Abstract
Major progress has been achieved in the chemotherapy of acute lymphocytic leukemia. In general the sequence of progress in this disease has been as follows: production of complete remission; increase of the complete remission rate to greater than 70% of patients with combination therapy; demonstration that maintained remissions are longer than unmaintained remissions; increase in duration of remissions by intensive treatment, combination therapy, optimized dose schedules, cyclic therapy, and intermittent reinduction; and substantial increase in survival [1, 2, 3, 4, 5, 6, 7, 8, 9]. Progress in the treatment of adults with acute myelogenous leukemia has lagged. While there are a few agents capable of producing complete remission in a minority of patients, remission induction programs capable of producing complete remission in the majority of patients have yet to be defined. This article will describe our efforts over the past three years to improve the complete remission rate in adult acute myelogenous leukemia.
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Freireich, E.J., Bodey, G.P., Hart, S., Rodriguez, V., Whitecar, J.P., Frei, E. (1970). Remission Induction in Adults with Acute Myelogenous Leukemia. In: Mathé, G. (eds) Advances in the Treatment of Acute (Blastic) Leukemias. Recent Results in Cancer Research / Fortschritte der Krebsforschung / Progrès dans les recherches sur le cancer, vol 30 . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-35334-9_16
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DOI: https://doi.org/10.1007/978-3-662-35334-9_16
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