Abstract
Transauricular hypophysectomy was performed on male Wistar rats weighing approximately 100 g. The average body and pancreas weights 52 weeks after hypophysectomy were 133 ± 25 g and 0.25 ± 0.04 g, respectively. The pancreatic weight was 0.19% of the body weight, which was less than that of nonhypophysectomized rats (0.25%). The pancreas appeared slightly thin when fresh and in situ, but normal in color.
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References
Baker BL (1958) Restoration of involuted zymogenic cells in hypophysectomized rats by replacement therapy. Anat Rec 131:389–403
Baker BL, Clapp HW, Annable CR, Dewey MM (1961) Elevation of proteolytic activity in the pancreas of hypophysectomized rats by hormonal therapy. Proc Soc Exp Biol Med 108:238–242
Bicknell JM, Baker BL (1962) Influence of hypophysectomy on lipolytic activity of the rat pancreas. Endocrinology 71:853–856
Cheah JS, Chua SP, Ho CL (1975) Ultrastructure of the skeletal muscles in acromegaly — before and after hypophysectomy. Am J Med Sci 269:183–187
Daigeler R (1981) Sex-dependent changes in the rat kidney after hypophysectomy. Cell Tissue Res 216:423–443
Gaal JM, Kovacs K, Sellers EA (1976) Effect of hypophysectomy and short- and long-term propylthiouracil treatment on the rat thyroid. Transmission and electron-microscopy. Acta Anat 96:356–365
Lando D, Secchi J, Roche J, Raynaud JP (1980) Adrenocorticotropin analogs and glucocorticoids in the hypophysectomized rat. I. Effects on liver polyribosomes and rough endoplasmic reticulum. Endocrinology 107:2055–2062
Linck G, Porte A (1981) B-cells of the synovial membrane. IV. Ultrastructural evidence of secretory variations in hypophysectomized or propylthiouracyl-treated mice. Cell Tissue Res 218:123–128
Mayston PD, Barrowman JA (1973) Influence of chronic administration of pentagastrin on the pancreas in hypophysectomized rats. Gastroenterology 64:391–399
Sesso A, Valeri V (1962) Effect of hypophysectomy on the amylase and trypsin. Activatable protease activities in the pancreatic juice and pancreatic acinar cell of the rat. Pflugers Arch Physiol 274:345–355
Sharawy M, Penney DP (1973) Unusual mitochondrial morphology in the rat adrenal cortex following hypophysectomy. Am J Anat 136:395–401
Smith HE, Page E (1976) Morphometry of rat heart mitochondrial subcompartments and membranes: application to myocardial cell atrophy after hypophysectomy. J Ultrastruct Res 55:31–41
Wenger T (1976) Ultrastructural changes in the vascular organ of the lamina terminalis following ovariectomy and hypophysectomy in the rat. Brain Res 101:95–102
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© 1997 Springer-Verlag Berlin Heidelberg
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Konishi, Y. (1997). Exocrine Pancreas of Hypophysectomized Rats. In: Jones, T.C., Popp, J.A., Mohr, U. (eds) Digestive System. Monographs on Pathology of Laboratory Animals, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-25996-2_43
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DOI: https://doi.org/10.1007/978-3-662-25996-2_43
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-0-944398-75-3
Online ISBN: 978-3-662-25996-2
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