Skip to main content
SpringerLink
Log in

Intranuclear and Intracytoplasmic Inclusions, Liver, Rat

  • Chapter
Book cover Digestive System

Part of the book series: Monographs on Pathology of Laboratory Animals ((LABORATORY,volume 3))

Abstract

Intranuclear and intracytoplasmic inclusions are not visible grossly.

This is a preview of subscription content, log in via an institution to check access.

Access this chapter

Log in via an institution
Chapter
USD 29.95
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
eBook
USD 39.99
Price excludes VAT (USA)
  • Available as PDF
  • Read on any device
  • Instant download
  • Own it forever
Softcover Book
USD 54.99
Price excludes VAT (USA)
  • Compact, lightweight edition
  • Dispatched in 3 to 5 business days
  • Free shipping worldwide - see info

Tax calculation will be finalised at checkout

Purchases are for personal use only

Institutional subscriptions

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  • Andrew W (1962) An electron microscope study of age changes in the liver of the mouse. Am J Anat 110: 1–18

    Article  PubMed  CAS  Google Scholar 

  • Andrew W, Brown HM, Johnson JB (1943) Senile changes in the liver of mouse and man, with special reference to the similarity of the nuclear alterations. Am J Anat 72: 199–221

    Article  Google Scholar 

  • Carr RD, Smith MJ, Keil PG (1960) The liver in the aging process. Histology. Arch Pathol 70: 15–18

    Google Scholar 

  • Dekker A, Krause JR (1973) Hyaline globules in human neoplasms. A report of three autopsy cases. Arch Pathol 95: 178–181

    PubMed  CAS  Google Scholar 

  • Edwards JE, White J (1941) Pathologic changes, with special reference to pigmentation and classification of hepatic tumors in rats fed p-dimethylaminoazobenzene (butter yellow). JNCI 2: 157–183

    CAS  Google Scholar 

  • Frith CH, Ward JM (1980) A morphologic classification of proliferative and neoplastic hepatic lesions in mice. J Environ Pathol Toxicol 3: 329–351

    Google Scholar 

  • Helyer BJ, Petrelli M (1978) Cytoplasmic inclusions in spontaneous hepatomas of CBA/H-T6T6 mice. Histochemistry and electron microscopy. JNCI 60: 861–869

    PubMed  CAS  Google Scholar 

  • Herbst M (1976) Glycogenous hepatonuclear inclusions in the aged mouse — an electron microscopic study of the histogenesis of nuclear inclusions. Pathol Eur 11: 69–79

    PubMed  CAS  Google Scholar 

  • Hollander CF (1967) Preliminary note on the relations between regenerative growth, ageing and tumor formation in the mouse liver. Epatologia 13: 447–454

    Google Scholar 

  • Hollander CF, Thung PJ (1966) Relations between regenerative growth and ageing in the mouse liver. In: Lindop PJ, Sacher GA (eds) Proc colloq on radiation and ageing. Taylor and Francis, London, pp 3–14

    Google Scholar 

  • Jacoby RO, Bhatt PN, Jonas AM (1979) Viral diseases. In: Baker HJ, Lindsey JR, Weisbroth SH (eds) The laboratory rat, vol I. Biology and diseases. Academic, New York, chap 11, pp 271–306

    Google Scholar 

  • Jones TC (1967) Pathology of the liver of rats and mice. In: Cotchin E, Roe FJC (eds) Pathology of laboratory rats and mice. Blackwell Scientific, Oxford, chap 1, pp 1–23

    Google Scholar 

  • Kleinfeld RG, Greider MH, Frajola WJ (1956) Electron microscopy of intranuclear inclusions found in human and rat liver parenchymal cells. J Biophys Biochem Cytol 2 [Suppl]: 435–438

    Article  PubMed  Google Scholar 

  • Lussier G, Pavilanis V (1968) Nuclear inclusions in the liver cells of the golden hamster. Can J Comp Med 32: 568–570

    PubMed  CAS  Google Scholar 

  • McClure HM, Chapman WL Jr. HooperBE, Smith FG, Fletchert OJ (1978) The digestive system. In: Benirschke K, Garner FM, Jones TC (eds) Pathology of laboratory animals, vol 1. Springer, New York Heidelberg Berlin, chap 4, pp 175–317

    Chapter  Google Scholar 

  • Nakanuma Y, Ohta G, Matsubara F, Wantanabe K, Doishita K (1982) Cytoplasmic blood plasma inclusions in human hepatocytes. Liver 2: 212–221

    PubMed  CAS  Google Scholar 

  • Popper H, Paronetto F, Barka T (1960) PAS-positive structures of nonglycogenic character in normal and abnormal liver. Arch Pathol 70: 300–313

    PubMed  CAS  Google Scholar 

  • Richter WR, Stein RJ, Rdzok EJ, Moize SM, Bischoff MB (1965) Ultrastructural studies of intranuclear crystalline inclusions in the liver of the dog. Am J Pathol 47: 587–599

    PubMed  CAS  Google Scholar 

  • Rijhsinghani K, Krakower C, Swerdlow M, Abrahams C, Ghose T (1980) Alpha-1-antitrypsin in intracellular inclusions of diethylnitrosamine induced hepatomas of C57BL X C3HF1 mice. Carcinogenesis 1: 473–479

    Article  PubMed  CAS  Google Scholar 

  • Ruebner BH, Lindsey JR, Melby EC Jr (1965) Hepatitis and other spontaneous liver lesions of small experimental animals. In: Ribelin WE, McCoy JR (eds) The pathology of laboratory animals. Thomas, Springfield, chap 7, pp 160–182

    Google Scholar 

  • Schauer A, Kunze E (1976) Tumours of the liver. In: Turusov VS (ed) Pathology of tumours in laboratory animals, vol I: tumours of the rat, part 2. IARC, Lyon, pp 41–72 (IARC scientific publications no 6)

    Google Scholar 

  • Wharton FP, Wright DJM (1977) Observations on a new liver inclusion in the mouse. Lab Anim 11: 109–111

    Article  PubMed  CAS  Google Scholar 

Download references

Authors
  1. Matthew J. van Zwieten
    View author publications

    You can also search for this author in PubMed Google Scholar

  2. Carel F. Hollander
    View author publications

    You can also search for this author in PubMed Google Scholar

Editor information

Editors and Affiliations

  1. ILSI Research Foundation, Harvard Medical School, 1126 Sixteenth Street. N.W., Washington, DC, 20036, USA

    Thomas Carlyle Jones D.V.M., D.Sc. (Professor of Comparative Pathology, Emeritus) (Professor of Comparative Pathology, Emeritus)

  2. Sanofi Winthrop, Toxicology U.S., Nine Great Valley Parkway, Malvern, PA, 19355, USA

    James A. Popp D.V.M., Ph.D. (International Director of Toxicology, Vice President) (International Director of Toxicology, Vice President)

  3. Medizinische Hochschule Hannover, Institut für Experimentelle Pathologie, Konstanty-Gutschow-Strasse 8, 30625, Hannover, Germany

    Ulrich Mohr M.D. (Professor of Experimental Pathology) (Professor of Experimental Pathology)

Rights and permissions

Reprints and permissions

Copyright information

© 1997 Springer-Verlag Berlin Heidelberg

About this chapter

Cite this chapter

van Zwieten, M.J., Hollander, C.F. (1997). Intranuclear and Intracytoplasmic Inclusions, Liver, Rat. In: Jones, T.C., Popp, J.A., Mohr, U. (eds) Digestive System. Monographs on Pathology of Laboratory Animals, vol 3. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-25996-2_16

Download citation

  • DOI: https://doi.org/10.1007/978-3-662-25996-2_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-0-944398-75-3

  • Online ISBN: 978-3-662-25996-2

  • eBook Packages: Springer Book Archive

Publish with us

Policies and ethics

Search

Navigation