Temporal Resolution of Heat Exchange during Action Potential of Nerve

  • C. S. Spyropoulos


The response of nerves or electric organs is known to be accompanied by heat production followed by an absorption [1–3]. The present author previously found that the response of a number of tissues was initiated at a threshold by a sudden reduction in the temperature and “abolished” at a threshold by a sudden increase in temperature of the preparation [4]. In addition it was found in the squid axon and in other tissues that by an appropriate combination of a thermal source and a voltage source almost any point in the I—V plane was an operating point [5–7]. These findings have prompted the author to attempt to obtain a temporal resolution of heat exchange during the action potential. The results are briefly presented in this communication.


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    Abbott, B. C., A. V. Hill. and J. V. Howarth, 1958: Proc. Roy. Soc. (London) B 14. 8, 149.Google Scholar
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    Hill, A. V., and J. V. Howarth, 1958: Proc. Roy. Soc. ( London) B 149, 167.Google Scholar
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    Abbott, B. C., X. Aube r t, and A. Fessard, 1958: J. Physiol. (Paris) 50, 99.Google Scholar
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    Spyropoulos, C. S., 1961: Amer. J. Physiol. 200, 203; other communication involving nitella and squid axon in preparation.Google Scholar
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    Spyropoulos, C. S., 1964: Il Nuovo Cimento 34, 1837.CrossRefGoogle Scholar
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    Spyropoulos, C. S., 1965: J. Gen. Physiol. 48, 49.Google Scholar
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    Spyropoulos, C. S., 1966: J. Brain Res. 1, 105.CrossRefGoogle Scholar

Copyright information

© Springer-Verlag Wien 1967

Authors and Affiliations

  • C. S. Spyropoulos
    • 1
    • 2
  1. 1.Institute of PhysicsUniversity of GenovaItaly
  2. 2.Department of PhysiologyUniversity of ChicagoChicagoUSA

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