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The Transporters Associated with Antigen Processing (TAP)

  • Chapter
Unusual Secretory Pathways: From Bacteria to Man

Part of the book series: Molecular Biology Intelligence Unit ((MBIU))

Abstract

Class I molecules of the major histocompatibility complex (MHC) present peptides derived from endogenous proteins at the cell surface. During viral infection or malignant transformation a different set of peptides is displayed by MHC class I molecules. These antigen-loaded class I complexes are recognized by cytotoxic T cells via the T cell receptors as nonself, thus leading to the destruction of the abnormal cell.

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Authors
  1. Robert Tampé
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  2. Stefanie Urlinger
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  3. Kurt Pawlitschko
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  4. Stephan Uebel
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© 1997 Springer-Verlag Berlin Heidelberg

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Tampé, R., Urlinger, S., Pawlitschko, K., Uebel, S. (1997). The Transporters Associated with Antigen Processing (TAP). In: Unusual Secretory Pathways: From Bacteria to Man. Molecular Biology Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-22581-3_4

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  • DOI: https://doi.org/10.1007/978-3-662-22581-3_4

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-22583-7

  • Online ISBN: 978-3-662-22581-3

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