Zusammenfassung
Die Leber ist das zentrale Stoffwechselorgan des Organismus. Ihre Funktion besteht in zahlreichen Stoffwechselreaktionen, durch die die aus dem Darm über die Pfortader zugeführten Zucker und Aminosäuren und die vorwiegend auf dem Umweg über den Ductus thoracicus zuströmenden Fette umgesetzt werden. Das beim Erythrozytenabbau in der Milz und dem übrigen RES freigesetzte Bilirubin wird über die Galle ausgeschieden. Zahlreiche endogene und exogene Substanzen werden durch Koppelung an Glukuronsäure, Sulfat oder Glykokoll „entgiftet“, d.h. wasserlöslich und harnfähig gemacht. Aus Aminogruppen bzw. Ammoniak wird Harnstoff gebildet. Die meisten Gerinnungsfaktoren werden in der Leber synthetisiert.
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Wehinger, H., Stephan, U., Wiesemann, H.G., Götze, H. (1994). Leber und Pankreas. In: Reinhardt, D. (eds) Therapie der Krankheiten des Kindesalters. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-22535-6_14
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DOI: https://doi.org/10.1007/978-3-662-22535-6_14
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