Abstract
Most cells in intact higher organisms are in contact with an extracellular matrix (ECM) composed of both protein and carbohydrate in the form of glycoproteins and proteoglycans (Hay 1981). Decades ago it was postulated that the ECM plays an important role in the development and maintenance of the differentiated state and it is now generally accepted that the ECM is fundamental in the regulation of development and in differentiation (Martin and Timpl 1987; Adams and Watt 1993). One specialized form of the ECM is the basement membrane.
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Dym, M. (1994). Extracellular Matrix Elements, Cell Adhesion Molecules, and Signal Transduction in the Control of Sertoli Cell Function. In: Verhoeven, G., Habenicht, UF. (eds) Molecular and Cellular Endocrinology of the Testis. Ernst Schering Research Foundation Workshop, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-22189-1_5
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DOI: https://doi.org/10.1007/978-3-662-22189-1_5
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