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Pharmakologische Therapie von Vorhofflimmern/Vorhofflattern

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Vorhofflimmern Vorhofflattern

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Zusammenfassung

Die primäre Behandlung des Vorhofflimmerns ist auch zu Beginn des 21. Jahrhunderts eine Domäne der medikamentösen Therapie. Es ist davon auszugehen, daß von den Patienten, die wegen symptomatischen Vorhofflimmerns den Arzt aufsuchen, mehr als 90% primär eine medikamentöse Behandlung erhalten. Auch bei Anwendung interventioneller Behandlungsformen kommt in Form der sogenannten Hybridtherapie [17] häufig eine medikamentöse Begleittherapie zum Tragen, so daß auf absehbare Zeit an der Dominanz pharmakologischer Therapieansätze kaum Änderungen zu erwarten sind.

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Literatur

  1. Brachmann J, Karolyi L, Kübier W (1998) Atrial dispersion of refractoriness. J Cardiovasc Electrophysiol 9:35–39.

    Google Scholar 

  2. Capucci A, Villani GQ, Aschieri D, Piepoli M (1998) Effects of class III drugs on atrial fibrillation. J Cardiovasc Electrophysiol 9:109–120.

    Article  Google Scholar 

  3. Coplen SE, Antman EM, Berlin JA, Hewitt P, Chalmers TC (1990) Efficacy and safety of quinidine therapy for maintenance of sinus rhythm after cardioversion. A meta-analysis of randomized control trials [published erratum appears in Circulation 1991; 83(2):714]. Circulation 82:1106–1116.

    Article  PubMed  CAS  Google Scholar 

  4. Coumel P (1990) Clinical approach to paroxysmal atrial fibrillation. Clin Cardiol 13:209–212.

    Article  PubMed  CAS  Google Scholar 

  5. Deedwania PC, Singh BN, Ellenbogen KA et al (1998) Spontaneous conversion and maintenance of sinus rhythm by amiodarone in patients with heart failure and atrial fibrillation. Circulation 98:2574–2579.

    Article  PubMed  CAS  Google Scholar 

  6. Falk RH, Pollak A, Singh S, Friedrich T (1997) Intravenous dofetilide, a class III antiarrhythmic agent, for the termination of sustained atrial fibrillation or flutter. J Am Coll Cardiol 29:385–390.

    Article  PubMed  CAS  Google Scholar 

  7. Flaker GC, Blackshear JL, Mc Bride R (1992) On behalf of the Stroke Prevention in Atrial Fibrillation Investigators: Antiarrhythmic drug therapy and cardiac mortality. J Am Coll Cardiol 20:527–532.

    Article  PubMed  CAS  Google Scholar 

  8. Golzari H, Cebul RD, Bahler RC (1996) Atrial fibrillation: Restoration and maintenance of sinus rhythm and indications for anticoagulation therapy. Ann Intern Med 125:311–323.

    PubMed  CAS  Google Scholar 

  9. Hohnloser SH, Kuck KH (1998) Atrial fibrillation — maintaining sinus rhythm versus ventricular rate control: the PIAF trial. Pharmacological Intervention in Atrial Fibrillation. J Cardiovasc Electrophysiol 8:21–126.

    Google Scholar 

  10. Hohnloser SH, Singh BN (1995) Proarrhythmia with class III antiarrhythmic drugs: definition, electrophysiologic mechanisms, incidence, predisposing factors, and clinical implications. J Cardiovasc Electrophysiol 10:920–936.

    Article  Google Scholar 

  11. Hohnloser SH, van de Loo A, Baedeker F (1995) Efficacy and proarrhythmic hazards of pharmacologic cardioversion of atrial fibrillation: prospective comparison of sotalol versus quinidine. J Am Coll Cardiol 26:852–858.

    Article  PubMed  CAS  Google Scholar 

  12. Hohnloser SH, Klingenheben T, Singh BN (1994) Amiodarone-associated proarrhythmic effects: A review with special reference to torsade de pointes tachycardia. Ann Intern Med 121:529–535.

    PubMed  CAS  Google Scholar 

  13. Hohnloser SH, Meinertz T, Dammbacher T et al (1991) Electrocardiographic and antiarrhythmic effects of intravenous amiodarone: Results of a prospective, placebo-controlled study. Am Heart J 121:89–94.

    Article  PubMed  CAS  Google Scholar 

  14. Hondeghem LM, Snyders DJ (1990) Class III antiarrhythmic agents have a lot of potential but a long way to go: Reduced effectiveness and the dangers of reverse use dependence. Circulation 81:686–690.

    Article  PubMed  CAS  Google Scholar 

  15. Kumar A (1996) Intravenous amiodarone for therapy of atrial fibrillation patients with severely depressed left ventricular function. South Med J 89:779–785.

    Article  PubMed  CAS  Google Scholar 

  16. Laupacis A, Boysen G, Connolly S et al (1994) For the Atrial Fibrillation Investigators: Risk factors for stroke and efficacy of antithrombotic therapy in atrial fibrillation. Analysis of pooled data from five randomized controlled trials. Arch Intern Med 154:1449–1457.

    Article  Google Scholar 

  17. Lesh MD, Kaiman JM, Roithinger FX, Karch MR (1997) Potential role of „hybrid therapy“ for atrial fibrillation. Semin Interv Cardiol 2:167–271.

    Google Scholar 

  18. Levy S, Novella P, Ricard P, Paganelli F (1995) Paroxysmal atrial fibrillation: A need for classification. J Cardiovasc Electrophysiol 6:69–74.

    Article  PubMed  CAS  Google Scholar 

  19. Maisel WH, Kuntz K, Reimold SC et al (1997) Risk of initiating antiarrhythmic drug therapy for atrial fibrillation in patients admitted to a university hospital. Ann Intern Med 127:281–284.

    PubMed  CAS  Google Scholar 

  20. Matsuda M, Matsuda Y, Yamgishi T et al (1991) Effects of digoxin, propanolol and verapamil on exercise in patients with chronic isolated atrial fibrillation. Cardiovasc Res 453-457.

    Google Scholar 

  21. Nattel S (1995) Newer developments in the management of atrial fibrillation. Am Heart J 130:1094–1106.

    Article  PubMed  CAS  Google Scholar 

  22. Nattel S, Hadjis T, Taljic M (1994) The treatment of atrial fibrillation — An evaluation of drug therapy, electrical modalities and therapeutic considerations. Drugs 48:345–371.

    Article  PubMed  CAS  Google Scholar 

  23. Philippon F, Plump VJ, Epstein AE (1995) The risk of atrial fibrillation following radiofrequency catheter ablation of atrial flutter. Circulation 92:30–435.

    Article  Google Scholar 

  24. Prystowsky EN, Benson WD, Fuster V et al (1996) Management of patients with atrial fibrillation. A statement for health care professionals from the subcommittee on electrocardiography and electrophysiology, American Heart Association. Circulation 93:1262–1277.

    Article  PubMed  CAS  Google Scholar 

  25. Redfors A (1971) Digoxin dosage and ventricular rate at rest and exercise in patients with atrial fibrillatin. Acta Med Scand 190:321–333.

    Article  PubMed  CAS  Google Scholar 

  26. Sasabe N, Saitoh H, Miyauchi Y (1993) Role of the autonomic nerve in the genesis of atrial fibrillation by heart rate variability spectral analysis. Circulation 18-18 (abstr).

    Google Scholar 

  27. Singh BN (1997) Acute conversion of atrial flutter and fibrillation: Direct current cardioversion versus intravenously administered pure class III agents. J Am Coll Cardiol 29:391–393.

    Article  PubMed  CAS  Google Scholar 

  28. Singh BN, Venkaesh N, Nademanee K (1989) The historical development, cellular electrophysiology and pharmacology of amiodarone. Prog Cardiovasc Dis 31:249–280.

    Article  PubMed  CAS  Google Scholar 

  29. Sonntag F (1998) PAFAC — SOPAT: mehr als zwei Akronyme. Herz 23:61–63.

    Article  Google Scholar 

  30. Sopher SM, Camm AJ (1996) Atrial fibrillation: maintenance of sinus rhythm versus rate control. Am J Cardiol 77:24A–37A.

    Article  PubMed  CAS  Google Scholar 

  31. Stambler BS, Wood MA, Ellenbogen KA, Perry KT, Wakefield LK, VanderLugt JT (1996) Efficacy and safety of repeated intravenous doses of ibutilide for rapid conversion of atrial flutter or fibrillation. Circulation 94:1613–1621.

    Article  PubMed  CAS  Google Scholar 

  32. The Digitalis in Acute Atrial Fibrillation (DAAF) Trial Group (1997) Intravenous digoxin in acute atrial fibrillation. Eur Heart J 18:649–654.

    Article  Google Scholar 

  33. The NHLBI AFFIRM investigators (1997) Atrial fibrillation follow-up investigation of rhythm management — the AFFIRM study design. The planning and steering Committees of the AFFIRM study. Am J Cardiol 79:1198–1202.

    Article  Google Scholar 

  34. van den Berg MP, Haaksma J, Brouwer J (1995) Analysis of heart rate variability in a patient with paroxysmal atrial fibrillation. Eur Heart J 16:2011–2012.

    PubMed  Google Scholar 

  35. Waldo AL, Cooper TB (1996) Spontaneous onset of type I atrial flutter in patients. J Am Coll Cardiol 28:707–712.

    Article  PubMed  CAS  Google Scholar 

  36. Yurchak PM, Williams SV, Achord JL et al (1993) Clinical competence in elective direct current (DC) cardioversion. A statement for physicians from the AHA/ ACC/ACP Task Force on Clinical Privileges in Cardiology. Circulation 88:342–345.

    Article  PubMed  CAS  Google Scholar 

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Authors
  1. G. C. Grönefeld
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  2. Y.-G. Li
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  3. B. Bender
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  4. S. H. Hohnloser
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Editor information

Editors and Affiliations

  1. Abt. für Kardiologie, Kerckhoff-Klinik, Benekestraße 2-8, 61231, Bad Nauheim, Deutschland

    Jörg Neuzner  & Heinz F. Pitschner  & 

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© 2000 Springer-Verlag Berlin Heidelberg

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Grönefeld, G.C., Li, YG., Bender, B., Hohnloser, S.H. (2000). Pharmakologische Therapie von Vorhofflimmern/Vorhofflattern. In: Neuzner, J., Pitschner, H.F. (eds) Vorhofflimmern Vorhofflattern. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-13383-5_6

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  • DOI: https://doi.org/10.1007/978-3-662-13383-5_6

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-662-13384-2

  • Online ISBN: 978-3-662-13383-5

  • eBook Packages: Springer Book Archive

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