Abstract
Some of the multiple and varied patterns of mammary epithelial hyperplasia have created concern about their implication for breast cancer risk, particularly since recent studies have shown such predictive implications.1,2 We have recognized a pattern of hyperplasia in the female breast, which resembles that seen in the florid phase of gynecomastia. The concern engendered by this pattern of hyperplasia in women comes directly from its similarity to micro-papillary carcinoma in situ of the ductal type1 and some related patterns accepted as atypical hyperplasia of ductal pattern. This pattern, however, does not have a proven association with an increased risk of breast cancer. This study is presented in order to recognize this special pattern of mammary epithelial hyperplasia, despite its merging into other patterns, and to highlight that it does not indicate cause for concern.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Page DL, Anderson TJ, Rogers LW: Epithelial hyperplasia. Carcinoma in situ (CIS), in Page DL, Anderson TJ: Diagnostic histopathology of breast, Edinburgh, Churchill Livingston, 1987, 120–192
Page DL, Dupont WD, Rogers LW, Rados MS: Atypical hyperplastic lesions of the female breast. A long-term follow-up study. Cancer 55:2698–2708, 1985
Bannayan GA, Hajdu SI: Gynecomastia: Clinico-pathologic Study of 351 Cases, Am J Clin Pathol 57:431–437, 1972
Karsner HT: Gynecomastia. Am J Pathol 22:235–315, 1946
Nicolis GL, Modlinger RS, Gabrilove JL: A study of the histopathology of human gynecomastia. J Clin Endocrinol 32:173–178, 1971
Oberman HA: Benign breast lesions confused with carcinoma, in McDivitt RW, Oberman HA, Ozzello L, Kaufman N (eds): The Breast, Baltimore, Williams and Wilkins 1984, 1–33
Dupont WD, Page DL: Risk factors for breast cancer in women with proliferative breast disease. New Engl J Med 312:146–151, 1985
Rosen PP: Subareolar sclerosing duct hyperplasia of the breast. Cancer 59:1927–1930, 1987
Rosen PP: Papillary duct hyperplasia of the breast in children and young adults. Cancer 56:1611–1617, 1985
Rosen PP, Holmes G, Lesser ML, et al: Juvenile papillomatosis and breast carcinoma. Cancer 55:1345–1352, 1985
Mies C, Rosen PP: Juvenile fibroadenoma with atypical epithelial hyperplasia. Am J Surg Pathol 11:184–190, 1987
Jones DB: Florid papillomatosis of the nipple ducts. Cancer 8:315–319, 1955
Perzin KH, Lattes R: Papillary adenoma of the nipple (florid papillomatosis, adenoma, adenomatosis). A clinicopathologic study. Cancer 29:996–1009, 1972
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1989 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Tham, KT., Dupont, W.D., Page, D.L., Gray, G.F., Rogers, L.W. (1989). Micro-Papillary Hyperplasia with Atypical Features in Female Breasts, Resembling Gynecomastia. In: Cecilia Fenoglio-Preiser, M., Wolff, M., Rilke, F. (eds) Progress in Surgical Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12823-7_6
Download citation
DOI: https://doi.org/10.1007/978-3-662-12823-7_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-12825-1
Online ISBN: 978-3-662-12823-7
eBook Packages: Springer Book Archive