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Carcinomas of the Breast with Signet Ring Cell and/or Squamous Metaplasia

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Progress in Surgical Pathology

Abstract

Carcinomas of the breast may show focal or extensive mucus production. Mucinous carcinomas1 are defined as cancers which have a large amount of extracellular epithelial mucus, whereas signet ring cell carcinomas contain intracellular deposits of PAS and/or Alcian Blue material. The latter tumors have been considered to be a variant of either lobular2 or ductal3 5 type of cancer on the basis of ultrastructural and/or histochemical investigations. Azzopardi6 reviewed the literature on this subject and proposed that both lobular and ductal type of signet ring cell variants could be encountered, an opinion shared by Hull and co-workers.7

This work was supported by grants from the Italian C.N.R. “Progetto Finalizzato Oncologia” (grant number 84.00478.44) from the Ministero Pubblica Istruzione (Rome) and the Associazione Italiana per la Ricerca sul Cancro (Milan).

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Authors
  1. Gianni Bussolati
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  2. Anna Sapino
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  3. Isabella Morra
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  4. Bruno Ghiringhello
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Editor information

Editors and Affiliations

  1. University of New Mexico, Albuquerque, New Mexico, USA

    Cecilia M. Fenoglio-Preiser M.D. (Professor of Pathology, Director of Laboratory Services) (Professor of Pathology, Director of Laboratory Services)

  2. Albuquerque Veterans Administration Medical Center, Albuquerque, New Mexico, USA

    Cecilia M. Fenoglio-Preiser M.D. (Professor of Pathology, Director of Laboratory Services) (Professor of Pathology, Director of Laboratory Services)

  3. Columbia University College of Physicians and Surgeons, Morristown, New Jersey, USA

    Marianne Wolff M.D. (Professor of Clinical Surgical Pathology) (Professor of Clinical Surgical Pathology)

  4. Department of Pathology, Memorial Hospital, Morristown, New Jersey, USA

    Marianne Wolff M.D. (Professor of Clinical Surgical Pathology) (Professor of Clinical Surgical Pathology)

  5. Division of Pathology and Cytology, The National Tumor Institute, Milan, Italy

    Franco Rilke M.D. (Director) (Director)

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© 1988 Springer-Verlag Berlin Heidelberg

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Bussolati, G., Sapino, A., Morra, I., Ghiringhello, B. (1988). Carcinomas of the Breast with Signet Ring Cell and/or Squamous Metaplasia. In: Fenoglio-Preiser, C.M., Wolff, M., Rilke, F. (eds) Progress in Surgical Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12820-6_15

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  • DOI: https://doi.org/10.1007/978-3-662-12820-6_15

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-12822-0

  • Online ISBN: 978-3-662-12820-6

  • eBook Packages: Springer Book Archive

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