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Diabetes and Ampullary Carcinoma: A Possible Relationship

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Progress in Surgical Pathology

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Abstract

MOST CARCINOMAS ARE NOT KNOWN to have a relationship to diabetes mellitus with the exception of primary pancreatic carcinomas, which do appear to have a predilection for maturity onset diabetics, particularly in patients over the age of 40.1–5 When we were reviewing mucosal neoplasms of the small bowel, it appeared as if there might be a possible relationship between diabetes and the presence of ampullary carcinoma.6 Of 51 surgically treated patients with primary small intestinal adenomas, more than one-half contained an invasive carcinoma arising in the adenoma. Four of the 51 patients were diabetic, and two others had first-degree diabetic relatives. These six individuals all had carcinomas arising in ampullary adenomas.

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Authors
  1. Mary Bridge
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Editors and Affiliations

  1. University of New Mexico, Albuquerque, New Mexico, USA

    Cecilia M. Fenoglio-Preiser M.D. (Professor of Pathology, Director of Laboratory Services) (Professor of Pathology, Director of Laboratory Services)

  2. Albuquerque Veterans Administration Medical Center, Albuquerque, New Mexico, USA

    Cecilia M. Fenoglio-Preiser M.D. (Professor of Pathology, Director of Laboratory Services) (Professor of Pathology, Director of Laboratory Services)

  3. Department of Pathology, Memorial Hospital, Columbia University College of Physicians and Surgeons, Morristown, New Jersey, USA

    Marianne Wolff M.D. (Professor of Clinical Surgical Pathology) (Professor of Clinical Surgical Pathology)

  4. Division of Pathology and Cytology, The National Tumor Institute, Milan, Italy

    Franco Rilke M.D. (Director) (Director)

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© 1986 Springer-Verlag Berlin Heidelberg

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Bridge, M. (1986). Diabetes and Ampullary Carcinoma: A Possible Relationship. In: Fenoglio-Preiser, C.M., Wolff, M., Rilke, F. (eds) Progress in Surgical Pathology. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12817-6_9

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  • DOI: https://doi.org/10.1007/978-3-662-12817-6_9

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-12819-0

  • Online ISBN: 978-3-662-12817-6

  • eBook Packages: Springer Book Archive

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