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Pädiatrie pp 584–624Cite as

Autoimmunkrankheiten

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Zusammenfassung

Das Immunsystem hat die Aufgabe, seinen Wirtsorganismus vor Infektionen zu schützen. Dafür muß das Immunsystem eine fast unbegrenzte Zahl von fremden Antigenen erkennen und gegen sie reagieren können, dieses Erkennen und/oder Reagieren darf aber nicht gegen körpereigene Antigene gerichtet sein. Die Diskriminierung zwischen Selbst- und Nichtselbstantigenen ist eine grundlegende Eigenschaft des Immunsystems. Die fehlende Reaktion des Immunsystems auf Selbstantigene ist als Selbsttoleranz definiert, der Verlust dieser Toleranz führt zur Autoimmunität, die dadurch verursachten Erkrankungen werden Autoimmunkrankheiten genannt.

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Authors
  1. G. Dannecker
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  2. P. Habermehl
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  3. E. Zepp
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  4. G. Ganser
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  5. H.-I. Huppertz
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  6. N. Wagner
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  7. C. Rieger
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  8. H. Michels
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  9. H. Truckenbrodt
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Editor information

Editors and Affiliations

  1. Universitäts-Kinderklinik, Adenauerallee 119, 53113, Bonn, Deutschland

    Michael J. Lentze

  2. Universitäts-Kinderklinik, Schwanenweg 20, 24105, Kiel, Deutschland

    Jürgen Schaub

  3. Universitäts-Kinderklinik, Martinistr. 52, 20246, Hamburg, Deutschland

    Franz J. Schulte

  4. Universitäts-Kinderklinik, Langenbeckstr. 1, 55101, Mainz, Deutschland

    Jürgen Spranger

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© 2001 Springer-Verlag Berlin Heidelberg

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Dannecker, G. et al. (2001). Autoimmunkrankheiten. In: Lentze, M.J., Schaub, J., Schulte, F.J., Spranger, J. (eds) Pädiatrie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12660-8_12

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  • DOI: https://doi.org/10.1007/978-3-662-12660-8_12

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-12661-5

  • Online ISBN: 978-3-662-12660-8

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