Zusammenfassung
Das akute Cor pulmonale ist definiert als akute Druckbelastung des rechten Ventrikels durch Anstieg des systolischen Drucks in der A. Pulmonalis auf über 3o mmHg oder des Mitteldrucks auf über 20 mmHg. In den meisten Fällen liegt dem akutem Cor pulmonale eine Lungenembolie zugrunde.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
Albador J, Niewenhaus HK, Sixma JJ (1989) Treatment of acute venous thromboembolism with low molecular weight heparin (fragmin). Circulation 8o: 935–940
Basu D, Gallus A, Hirsh J, Cade J (1992) A prospective study of the value of monitoring heparin treatment with the activated partial thromboplastin time. N Engl J Med 287: 324–327
Bell WR, Simon TL (1982) Current status of pulmonary thromboembolic disease: Pathophysiology, diagnosis, prevention and treatment. Am Heart J 103: 239–262
Bertina RM, Koeleman BPC, Koster T et al. (1994) Mutation in blood coagulation factor V associated with resistance to activated protein C. Nature 369: 64
Blum AG, Delfau F, Grignon B et al. (1994) Sprial-computed tornography vs. pulmonary angiography in the diagnosis of acute massive pulmonary embolism. Am J Cardiol 74: 96
Bouneameaux H, de Moerloose P, Perrier A, Reber G (1994) Plasma measurement of D-dimer as diagnostic aid in suspected venous thromboembolism. An overview. Thromb Haemost 71: 1
Brady AJB, Crake T, Oakley CM (1991) Precutanwous catheter fragmentation and distal dispersion of proximal pulmonary embolus. Lancet 338: 1186
Brandfonbrener M, Turino GM, Himmelstein A (1958) Effects of occlusion of one pulmonary artery on circulation in man. Fed Proc 17: 19
Collins R, Scrimgeour A, Yusuf S, Peto R (1988) Reduction in fatal pulmonary embolism and venous thrombosis by perioperative administration of subcutaneous heparin: Overview of resells of randomized trials in general, orthopaedic and urologie surgery. N Engl J Med 318: 1162
Dalen JE, Alper JS (1975) Natural history of pulmonary embolism. Frog Cardiovasc Disease 17: 259–270
Decousus H, Leizorovic A, Parent F et al. (1998) A clinical trial of vena caval filters in the prevention of pulmonary embolism in patients with proximal deep vein thrombosis. N Engl J Med 338: 409–415
Dunmire SM (1989) Pulmonary embolism. Emerg Med Clin North Am 7: 339–354
Goldhaber SZ, Haire WD, Feldstein MI, et al. (1993) Alteplase vs. heparin in acute pulmonary embolism: randomized trial assessing right-ventricular function and pulmonary perfusion. Lancet 270: 2819–2822
Goldhaber SZ, Kessler CM, Heit J et al. (1988) Randomised controlled trial of recombinant tissue plasminogen activator vs. urokinase in the treatment of acute pulmonary embolism. Lancet H: 293–298
Goldhaber SZ, Kessler CM, Heit JA et al. (1992) Recombinant tissue-type plasminogen activator vs. a novel dosing regimen of urokinase in acute pulmonary embolism: A randomized controlled multicenter trial. J Am Coll Cardiol 2o: 24–30
Goldhaber SZ, Simons GR, Elliott CG et al. (1993) Quantitative plasma D-dimer levels among patients undergoing pulmonary angiography for suspected pulmonary embolism. JAMA 270: 2819–2822
Gottschalk A, Sostmann HD, Coleman RE (1993) Ventilation -perfusion scintigraphy in the PI O PEI) study. Part II. Evaluation of the scintigraphie criteria and interpretations. J Nucl Med 34: II 19
Grosser KD (1988) Akute Lungenembolie. Behandlung nach Schweregraden. Dtsch Arztebl 85: 587–594
Bulbs DC, Schmid C, Borst I IG (1994) Medical compared with surgical treatment for massive pulmonary embolism. Lancet 343: 565
Hirsch DR, Lee Tll, Morrison RB et al. (1996) Shortened hospitalization by means of adjusted-dose subcutaneous heparin for deep venous thrombosis. Am Ilearl 113i: 276
Hirsch I (1995) The optimal duration of anticoagulant therapy for venous thrombosis. N Engl I Med 25: 1710–1711
HoellerickVL, Wigton RS (1986) Diagnosing pulmonary embolism using clinical findings. Arch Intern Med 146: 1699–1704
Horstkotte D, Heintzen MP, Strauer BE (1989) Kombinierte mechanische and thrombolytische Wiedereröffnung der Lungenstrombahn bei massiver Lungenartereinembolie mit kardiogenem Schock. Intensivmedizin 27: 124–132
Huisman MV, Buller HR, tenCate JW et al. (1989) Unexpected high prevalence of pulmonary embolism in patients with deep venous thrombosis. Chest 95: 498–502
Hull R, Hirsh J, Jay R et al. (1982) Different intensities of oral anticoagulant therapy in the treatment of proximal-vein thrombosis. N Engl J Med 307: 1676–1681
Jerjes-Sasnchez C, Ramirez-Rivera A, Garcia ML (1995) Streptokinase and heparin vs. heparin alone in massive pulmonary embolism: a randomized controlled trial. J Thromb Thrombolys 2: 227–9
Kasper W, Geibel A, Tiede N et al. (1993) Distinguishing between acute and subacute massive pulmonary embolism by conventional and Doppler echocardiography. Br Heart J 70: 352
Kasper W, Konstantinidis S, Geibel A et al. (1997) Management strategies and determinants of outcome in acute major pulmonary embolism: results of a multicenter registry. J Am Coll Cardiol 30: 1165–1171
Kniffin WD, Baron JA, BarettJ, Brikmeyer JD, Anderson FA (1994) The epidemiology of diagnosed pulmonary embolism and deep venous thrombosis is the elderly. Arch Intern Med 154: 861–866
Konstantinidis S, Geibel A, Olschewski M et al. (1997) Association between thrombolytic therapy and the prognosis of hemodynamically stable patients with major pulmonary embolism. Circulation 9: 882–888
Koster T, Rosendaal FR, de Ronde H et al. (5993) Venous thrombosis thrombophilia study. Lancet 342: 1503
Landefeld CS, Cook EF, Flatley M et al.(199o) Identification and preliminary validation of predictors of major bleedings in hospitalized patients staring anticoagulant therapy. Am J Med 82: 703
Leizorovicz A, Haugh MC, Chapuis FR et al. (1992) Low molecular weight heparin in prevention of perioperative thrombosis. BMJ 305: 913
Meaney JF, Weg JP, Chenevert TL et al. (1997) Diagnosis of pulmonary embolism with magnetic resonance angiography. N Engl J Med 336: 1422–1427
Meneveau N, Schiele F, Vuillemenot A et al. (1997) Streptokinase vs.alteplase in massive pulmonary embolism. A randomized trial assessing right heart hemodynamics and pulmonary vascular obstruction. Eur Heart J 18: 1141–1148
Merli GJ, Martinez J (1987) Prophylaxis for deep vein thrombosis and pulmonary embolism in surgical patients. Med Clin North Am 71: 377–397
Meyer G, Sors H, Charbonnier B et al. (1992) Effect of intravenous urokinase vs. alteplase on total pulmonary resistance in acute massive pulmonary embolism: a European multicenter double-blind trial. J Am Coll Cardiol 19: 239–245
Miniati M, Pistolesi M, Marini C et al. (1996) Value of perfusion lung scan in the diagnosis of pulmonary embolism: Results of the Prospective Investigative Study of acute Pulmonary Embolism Diagnosis ( PISA-PES ). Am J Respir Grit Care Med 154: 1397–1393
Monreal M, Lafoz E, Olive A, del Rio L, Vedia C (1994) Comparison of subcutaneous unfractionated heparin with a low molecular weight heparin (fragmin) in patients with venous thromboemholism and contraindications to coumarin. Thromb Haemost 71: 7-n
Moser KM (1990) Venous Thoomboembolism–State of the art. Am Rev Respir Dis 141: 235–249
Mussel D, Rosso J, Petitpretz Pet al. (1988) Acute pulmonary embolism: diagnostic value of digital subtraction angiography. Radiology 166 (2): 455–459
Myers TM, Hull RI), Wega IC (1980) Anlithrombotie therapy for venous lhromhocmbolic disease. Chest 89 (Suppl 2): 205–35 S
Novellini RA, Baltarowich OH, Athanasoulis CA et al. (1978) The clinical course of patients with suspected pulmonary embolism and a negative arteriogram. Radiology 120: 501–507
Oudkerk M, Beek EJ van, Putten WL van, Buller HR (1993) Cost-effectiveness analysis of varous strategies in the diagnostic management of pulmonary embolism. Arch Intern Med 153 (8): 947–954
Piers DB, Verziglberger F, Westerman CJ et al. (1987) A comparative study of intravenous digital subtraction angiography and ventilation-perfusion scans in suspected pulmonary embolism. Chest 91: 837–843
Piers DB, Verziglberger F, Westerman CJ, Ludwig JW (1987) A comparative study of intravenous digital subtraction angiography and ventilation-perfusion scans in suspected pulmonary embolism. Chest 91 /6: 837–43
PIOPED Investigators (1990) Value of the Ventilation/Perfusion Scan in acute pulmonary embolism. JAMA 263: 2753–2759
PIOPED Study Group (1990) Tissue-type plasminogen activator for the treatment of acute pulmonary embolism. Chest 97: 528–533
Raschke RA, Reilly BM, Guidry JR et al. (1993) The weight-based heparin dosing nomogram compared with a „standard care“ nomogram: A randomized controlled trial. Ann Intern Med 119: 874–881
Remy-Jardin M, Remy J, Artaud D et al. (1996) A Diagnosis of pulmonary embolism with spiral CT: comparison with pulmonary angiography and scintigraphy. Radiology zoo: 699–706
Remy-Jardin M, Remy J, Wattinne L, Giraud F (1992) Central pulmonary thromboembolism: Diagnosis with spiral volumentric CT with the single-breath-hold technique - comparison with pulmonary angiography. Radiology 185: 381–387
Rosso J, Musset D, Petitpretz P et al. (1989) Intravenous digital subtraction angiography and lung imaging: compared value in the diagnosis of pulmonary embolism. Clin Nucl Med 14 (3): 183–186
Schafer Al (1985) The hypercoagulable states. Ann Intern Med 102: 814–828
Schulman S, Rhedin AS, Lindmarker P et al. (1995) A comparison of 6 weeks with 6 month of oral anticoagulant therapy after a first episode of venous thromboembolism. N Engl J Med 332: 1661–1665
Silverstein MD, Heit JA, Mohr DN et al. (1998) Trends in the incidence of deep vein thrombosis and pulmonary embolism: a 25-year population-based study. Arch Inn Med 158: 585–593
Simioni G, Prandoni P, Lensing AW et al. (1997) The risk of recurrent venous thromboembolism in patients with an Arg 506 Gin mutation in the gene for factor V (factor V Leiden). N Engl J Med 336: 399–403
Simonneau G, Sors H, Charbonnier B et al. (1997) A comparison of low-molecular-weight heparin with unfractionated heparin for acute pulmonary embolism. N Engl J Med 62: 663–669
Siragusa S, Cosmi B, Peovella F, Hirsh J, Ginsberg JS (1995) Lowmolecular-weight heparins and unfractionated heparin in the treatment of patients with acute venous thromboembolism: Results of a meta-analysis. Am J Med 100: 269–277
Stein PD, Goldhaber SZ, Henry JW (1995) Alveolar-arterial oxygen gradient in the assessment of acute pulmonary embolism. Chest 107: 119
Stein PD, Terrill MI., Hales CA, Palevsky HI, Saltzman HA, Thompson BTG, Weg JG (1991) Clinical, laboratory roentgenographic and electrocardiographic findings in patients with acute pulmonary embolism and no pre-existing cardiac or pulmonary disease. Chest ton: 598–603
Svensson PJ, Dahlbäck B (1994) Resistance to activated protein C as a basis for venous thrombosis. N Engl J Sled 33o: 517
Thery C, Simonneau G, Meyer G et al. (1992) Randomized trial of subcutanous low-molecular-weight heparin CY ais (fraxiparine) compared with intravenous unfractionated heparin in the curative treatment of submasive pulmonary embolism. Circulation 85: 1380–1389
UPET Study Group (1970) Urokinase pulmonary embolism trial: phase 1: a cooperative study (UHT). JAMA 214: 163–210S
Van Rossuni AB, Treurniet FEE, Kieft GJ, Smith R, Sehepers-Bok R (1996) Role of spiral volumetric computed tomographie scanning in the assessment of patients with clinical suspicion of pulmonary embolism and an abnormal ventilation/perfusion lung scan. Thorax 51: 23–28
Virchow R (1862) Gesammelte Abhandlungen zur Wissenschaftlichen Medizin Vol IV: Thrombose und Embolie. G-Hamm-Grotesche Buchhandlung, Berlin, S 219
Warkentien TE, Levine MN, Hirsh J et al. (1995) Heparin-induced thrombocytopenia in patients treated with low molecular weight heparin or unfractionated heparin. N Engl J Med 332: 1330–1335
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2000 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Beuckelmann, D.J. (2000). Akutes Cor pulmonale und Lungenembolie. In: Erdmann, E. (eds) Klinische Kardiologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-12156-6_41
Download citation
DOI: https://doi.org/10.1007/978-3-662-12156-6_41
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-12157-3
Online ISBN: 978-3-662-12156-6
eBook Packages: Springer Book Archive