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Interventional Cardiology and Angiology pp 33–41Cite as

Adenosine production during balloon-induced ischemia

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Abstract

It is well established that myocardial metabolites play a significant role in the local adjustment of coronary blood flow (5, 19). Beside others (7, 19), vasoactive adenosine has been described to be a major factor involved in the metabolic control of coronary flow. Experimental studies have demonstrated that inadequate supply of oxygen to the heart, e.g. during ischemia, leads to enhanced formation of adenosine which in turn increases coronary flow to meet the enhanced oxygen requirement (6, 11, 22). According to these results adenosine is proposed to be involved in a feed-back controlled system in which the ratio between supply and demand of oxygen is the major trigger mechanism for enhanced production of adenosine by the heart (1, 5, 25).

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Author information

Authors and Affiliations

  1. Department of Anesthesiology, Klinikum Großhadern, University of Munich, Germany

    H. Bardenheuer, B. Höfling & A. Fabry

Authors
  1. H. Bardenheuer
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  2. B. Höfling
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  3. A. Fabry
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Editor information

Editors and Affiliations

  1. Medizinische Klinik I, Klinikum Großhadern, Marchioninistraße 15, 8000, München, Germany

    B. Höfling  & A. v. Pölnitz  & 

  2. Medizinische Klinik I, Klinikum Großhadern Universität München, Marchioninistr. 15, 8000, München 70, Germany

    E. Erdmann

  3. Medizinische Klinik I, Univ. Klinikum Großhadern, Marchioninistr. 70, 8000, München 70, Germany

    G. Steinbeck

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© 1989 Springer-Verlag Berlin Heidelberg

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Bardenheuer, H., Höfling, B., Fabry, A. (1989). Adenosine production during balloon-induced ischemia. In: Höfling, B., v. Pölnitz, A., Erdmann, E., Steinbeck, G., Strauer, B.E. (eds) Interventional Cardiology and Angiology. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-12114-6_5

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  • DOI: https://doi.org/10.1007/978-3-662-12114-6_5

  • Publisher Name: Steinkopff, Heidelberg

  • Print ISBN: 978-3-662-12116-0

  • Online ISBN: 978-3-662-12114-6

  • eBook Packages: Springer Book Archive

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