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The Mycelium as an Integrated Entity

  • Chapter
Book cover Growth, Differentiation and Sexuality

Part of the book series: The Mycota ((MYCOTA,volume 1))

Abstract

The morphology of a mycelium is determined by mechanisms which regulate the polarity and the direction of growth of hyphae and the frequency with which they branch. As implied by Pfennig (1984), these regulatory mechanisms make a significant contribution to the efficiency with which fungi colonise solid surfaces. Observation of a colony developing on a solid medium shows that hyphae grow radially outward from the inoculum with leading hyphae at the colony margin growing approximately parallel to one another and at approximately the same distance apart. The growth kinetics observed during the development of mycelia on solid media appear to be common to all molds, and even extend to filamentous streptomycetes (Allan and Prosser 1983, 1985).

Hyphal and mycelial growth appears to be an adaptation to life in inhomogeneous environments with solid surfaces, primarily soils.

Norbert Pfennig (1984)

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References

  • Allan EJ, Prosser JI (1983) Mycelial growth and branching of Streptomyces coelicolor A3(2) on solid medium. J Gen Microbiol 129:2129–2036

    Google Scholar 

  • Allan DJ, Prosser JI (1985) A kinetic study of the colony growth of Streptomyces coelicolor A3(2) and J802 on solid medium. J Gen Microbiol 131:2521–2036

    Google Scholar 

  • Aoki M, Itezono Y, Shirai H, Nakayama N, Akai A, Tanaka Y, Yamaguchi A, Shimma N, Yokose K, Seto H (1991) Structure of a novel phospholipase C inhibitor, vinaxanthone (Ro 09–1450) produced by Penicillium vinaceum. Tetrahedron Lett 32:4737–4740

    Article  CAS  Google Scholar 

  • Bailey JA, Vincent GG, Burden RS (1974) Diterpenes from Nicotiana glucinosa and their effect on fungal growth. J Gen Microbiol 85:57–64

    PubMed  CAS  Google Scholar 

  • Bailey JA, Carter GA, Burden RS, Wain RL (1975) Control of rust diseases by diterpenes from Nicotiana glucinosa. Nature 255:328–329

    Article  CAS  Google Scholar 

  • Barja F, Turian G (1992) Chlortetracycline fluorescent probing of Ca2+ sequestration in mitochondria fronting the acidic tip of germ tubes outgrowing from conidia of Neurospora crassa. Biomed Lett 47:35–38

    CAS  Google Scholar 

  • Barratt RW, Garnjobst L (1949) Genetics of a colonial microconidiating mutant strain of Neurospora crassa. Genetics 34:351–369

    PubMed  CAS  Google Scholar 

  • Bartelt DC, Fidel S, Farber LH, Wolff DJ, Hammeil H (1988) Calmodulin-dependent multifunctional protein kinase in Aspergillus nidulans. Proc Natl Acad Sci USA 85:3279–3283

    Article  PubMed  CAS  Google Scholar 

  • Bartnicki-Garcia S, Hergert F, Gierz G (1989) Computer simulation of fungal morphogenesis and the mathematical basis for hyphal (tip) growth. Protoplasma 153:46–57

    Article  Google Scholar 

  • Beadle GW, Coonradt VL (1944) Heterocaryosis in Neurospora crassa. Genetics 29:291–308

    PubMed  CAS  Google Scholar 

  • Berridge MJ (1993) Inositol trisphosphate and cell signalling. Nature 361:315–325

    Article  PubMed  CAS  Google Scholar 

  • Binks P, Robson GD, Goosey MW, Trinci APJ (1993) Inhibition of phosphatidylcholine and chitin biosynthesis in Pyricularia oryzae, Botrytis fabae and Fusarium gra-minearum by edifenphos. J Gen Microbiol. (in press)

    Google Scholar 

  • Blumenthal DK, Takio K, Hansen RS, Krebs EG (1986) Dephosphorylation of cAMP-dependent protein kinase regulatory sub-unit (Type II) by calmodulin-dependent enzymes. Biochem Biophys Res Commun 156:860–865

    Article  Google Scholar 

  • Bonnett HT, Newcomb EH (1966) Coated vesicles and other cytoplasmic components of growing root hairs of radish. Protoplasma 1:59–75

    Article  Google Scholar 

  • Brody S, Tatum EC (1966) The primary biochemical effect of a morphological mutation in Neurospora crassa. Proc Natl Acad Sci 56:1290–1297

    Article  PubMed  CAS  Google Scholar 

  • Brody S, Tatum EC (1967) Phosphoglucomutase mutants and morphological changes in Neurospora crassa. Proc Natl Acad Sci 58:923–930

    Article  PubMed  CAS  Google Scholar 

  • Bull AT, Trinci APJ (1977) The physiology and metabolic control of fungal growth. In: Rose AH, Tempest DW (eds) Advances in microbial physiology, vol 15. Academic Press, New York, pp 1–84

    Chapter  Google Scholar 

  • Burgoyne RD, Morgan A (1992) Phospholipid-binding proteins in calcium-dependent exocytosis. Trans Bio-chem Soc 20:834–836

    CAS  Google Scholar 

  • Caldwell IY, Trinci APJ (1973) The growth unit of the mould Geotrichum candidum. Arch Mikrobiol 88:1–10

    Article  PubMed  CAS  Google Scholar 

  • Campbell A (1957) Synchronization of cell division. Bacteriol Rev 21:253–272

    CAS  Google Scholar 

  • Collinge AJ, Trinci APJ (1974) Hyphal tips of wild-type and spreading colonial mutants of Neurospora crassa. Arch Microbiol 99:353–368

    Article  PubMed  CAS  Google Scholar 

  • Cornelius G, Nakashima H (1987) Vacuoles play a decisive role in calcium homeostasis. J Gen Microbiol 133:2341–2347

    CAS  Google Scholar 

  • Cornelius G, Gebauer G, Techel D (1989) Inositol tris-phosphate induces calcium release from Neurospora crassa vacuoles. Biochem Biophys Res Commun 162: 852–856

    Article  PubMed  CAS  Google Scholar 

  • Creutz C, Snyder SL, Kambouris NG (1991) Calcium-dependent secretory vesicle-binding and lipid-binding proteins of Saccharomyces cerevisiae. Yeast 7:229–244

    Article  PubMed  CAS  Google Scholar 

  • Dicker W, Turian G (1990) Calcium deficiencies and apical hyperbranching in wild-type and “frost” and “spray” morphological mutants of Neurospora crassa. J Gen Microbiol 136:1413–1420

    CAS  Google Scholar 

  • Doonan JH (1992) Cell division in Aspergillus. J Cell Sci 103:509–611

    Google Scholar 

  • Fiddy C, Trinci APJ (1976) Mitosis, septation and the duplication cycle in Aspergillus nidulans. J Gen Microbiol 97:169–184

    PubMed  CAS  Google Scholar 

  • Galpin MF, Jennings DH, Thornton JD (1977) Hyphal branching in Denaryphiella salina: effect of various compounds and further elucidation of the effect of sorbose and the role of cyclic AMP. Trans Br Mycol Soc 69:175–182

    Article  Google Scholar 

  • Galun E (1971) Morphogenesis in Trichoderma: induction of conidiation by narrow-beam illumination of restricted areas of the fungal colony. Plant Cell Physiol 12: 779–783

    Google Scholar 

  • Galun M, Malki D, Galun E (1981) Visualization of chitinwall formation in hyphal tips and anastomoses of Diploidia natalensis by fluorescein-conjugated wheat agglutinin and [3H]N-acetyl-D-glucosamine. Arch Microbiol 130:105–110

    Article  CAS  Google Scholar 

  • Garnjobst L, Tatum EL (1970) New crisp genes and crisp modifiers in Neurospora crassa. Genetics 66:281–290

    PubMed  CAS  Google Scholar 

  • Garrill A, Lew RR, Heath IB (1992) Stretch-activated Ca2+ and Ca2+-activated K+ channels in the hyphal tip plasma membrane of the oomycete Saprolegnia fer ax. J Cell Sci 101:721–730

    CAS  Google Scholar 

  • Girbardt M (1968) Ultrastructure and dynamics of the moving nuclei. In: Miller PL (ed) Aspects of cell motility. 23rd Symp Society for Experimental Biology. Cambridge University Press, Cambridge, pp 249–259

    Google Scholar 

  • Gooday GW (1971) An autoradiographic study of hyphal growth of some fungi. J Gen Microbiol 67:125–137

    CAS  Google Scholar 

  • Gooday GW, Trinci APJ (1980) Wall structure and biosynthesis in fungi. In: Gooday GW, Lloyd D, Trinci APJ (eds) The eukaryotic microbial cell. 30th Symp Society for General Microbiology, Cambridge University Press, Cambridge, pp 207–251

    Google Scholar 

  • Gregory PH (1984) The fungal mycelium: an historical perspective. Trans Br Mycol Soc 82:1–11

    Article  Google Scholar 

  • Hanson BA (1991) The effects of lithium on phosphoino-sitides and inositol phosphates of Neurospora crassa. Exp Mycol 15:76–90

    Article  CAS  Google Scholar 

  • Hanson BA, Brody S (1979) Lipid and cell wall changes in an inositol-requiring mutant of Neurospora crassa. J Bacteriol 138:461–466

    PubMed  CAS  Google Scholar 

  • Heizmann CW, Hunziker W (1991) Intracellular calcium-binding proteins: more sites than insights. TIBS 16:98–103

    PubMed  CAS  Google Scholar 

  • Higuchi S, Tamura J, Giri P, Polli JW, Kincaid RL (1991) Calmodulin-dependent protein phosphatase from Neurospora crassa. Molecular cloning and expression of recombinant catalytic subunit. J Biol Chem 266:18104–18112

    PubMed  CAS  Google Scholar 

  • Hiroyaki K, Uno I, Ishikawa T, Takenawa T (1989) Activation of phosphatidylinositol kinase and phospatidy-linositol-4-phosphate kinase by cAMP in Saccharomyces cerevisiae. J Biol Chem 264:3116–3121

    Google Scholar 

  • Howell CR (1978) Seed treatment with L-sorbose to control damping-off of cotton seedlings by Rhizoctonia solani. Phytopathology 68:1096–1098

    Article  CAS  Google Scholar 

  • Hutchinson SA, Sharma P, Clarke KR, MacDonald I (1980) Control of hyphal orientation in colonies of Mucor hiemalis. Trans Br Mycol Soc 75:177–191

    Article  Google Scholar 

  • Imoto M, Umezawa K, Takahashi Y, Naganawa H, Iitaka Y, Nakamura H, Koizumi Y, Sasaki Y, Hamada M, Sawa T, Takeuchi T (1990) Isolation and structure determination of inostamycin, a novel inhibitor of phosphatidylinositol turnover. J Nat Prod 53:825–829

    Article  CAS  Google Scholar 

  • Jackson SL, Heath IB (1989) Effects of exogenous calcium ions on tip growth, intracellular Ca2+ concentration, and actin arrays in hyphae of the fungus Saprolegnia ferax. Exp Mycol 13:1–12

    Article  Google Scholar 

  • Jejelowo OA, Trinci APJ (1988) Effect of the paramor-phogens, 3-O-methyl-D-glucose, glucosamine and l-sorbose on growth and morphology of Botrytis fabae. Trans Br Mycol Soc 91:653–660

    Article  CAS  Google Scholar 

  • Koenig R, Howard RL (1962) Nuclear division and septum formation in hyphal tips of Fusarium oxysporum. Am J Bot 49:666 (Abstr)

    Google Scholar 

  • Liu Y, Yamashita Y, Tsuchiya E, Miyakawa T (1990) Calmodulin-binding proteins of Saccharomyces cerevisiae. Biochem Biophys Res Commun 166:681–686

    Article  PubMed  CAS  Google Scholar 

  • Lu KP, Means AR (1993) Regulation of the cell cycle by calcium and calmodulin. Endocr Rev 14:40–58

    PubMed  CAS  Google Scholar 

  • Martinez-Cadena G, Ruiz-Herrera J (1987) Activation of chitin synthetase from Phycomyces blakesleeanus by calcium and calmodulin. Arch Microbiol 148:280–285

    Article  CAS  Google Scholar 

  • Melnick MB, Melnick C, Lee M, Woodward DO (1993) Structure and sequence of the calmodulin gene from Neurospora crassa. Biochim Biophys Acta 1171:334

    Article  PubMed  CAS  Google Scholar 

  • Miller DD, Callaham DA, Gross DJ, Hepler PK (1992) Free Ca2+ gradient in growing pollen tubes of Lihum. J Cell Sci 101:7–12

    CAS  Google Scholar 

  • Mishra NC (1976) The effect of cyclic adenosine monophosphate on the growth of Neurospora crassa. Naturwissenschaften 63:485

    Article  PubMed  CAS  Google Scholar 

  • Mishra NC, Tatum EL (1972) Effect of L-sorbose on polysaccharide synthetases of Neurospora crassa. Proc Natl Acad Sci USA 69:313–317

    Article  PubMed  CAS  Google Scholar 

  • Monod J (1949) The growth of bacterial cultures. Annu Rev Microbiol 3:371–394

    Article  CAS  Google Scholar 

  • Montgomery GWG, Gooday GW (1985) Phospholipid-enzyme interactions of chitin synthase of Coprinus cinereus. FEMS Microbiol Lett 27:29–33

    Article  CAS  Google Scholar 

  • Morris NR (1976) Mitotic mutants of Aspergillus nidulans. Gene Res 26:237–254

    Article  Google Scholar 

  • Nishioka H, Sawa T, Isshiki K, Takahashi Y, Naganawa H, Matsuda N, Hattori S, Hamada M, Takeuchi T (1991) Isolation and structure determination of a novel phosphatidylinositol turnover inhibitor, piericidin B1 N-oxide. J Antibiot 44:1283–1285

    Article  PubMed  CAS  Google Scholar 

  • Nobiling R, Reiss HD (1987) Quantitative analysis of calcium gradients and activity in growing pollen tubes of Lilium longiliflorum. Protoplasma 139:20–24

    Article  CAS  Google Scholar 

  • Nurse P (1990) On fission (the 1990 Marjory Stephenson Prize Lecture). J Gen Microbiol 136:1921–1923

    Google Scholar 

  • Oakley BR, Morris NR (1980) Nuclear movement is ß-tubulin dependent in Aspergillus nidulans. Cell 19:255–262

    Article  PubMed  CAS  Google Scholar 

  • Oakley BR, Morris NR (1981) A β-tubulin mutation in Aspergillus nidulans that blocks microtubule function without blocking assembly. Cell 24:837–845

    Article  PubMed  CAS  Google Scholar 

  • Oakley BR, Morris NR (1983) A mutation in Aspergillus nidulans that blocks the transition from interphase to prophase. J Cell Biol 96:1155–1158

    Article  PubMed  CAS  Google Scholar 

  • Oakley BR, Rinehart JE (1985) Mitochondria and nuclei move by different mechanisms in Aspergillus nidulans. J Cell Biol 101:2392–2397

    Article  PubMed  CAS  Google Scholar 

  • Ortega-Perez R, Turian G (1987) Cytomorphological defects produced by anti-calmodulin agents in outgrowing germ tubes and elongating hyphae of Neurospora crassa. Cytobiocs 49:137–145

    Google Scholar 

  • Ortega-Perez R, Van Tuinen D, Marme D, Turian G (1983) Calmodulin-stimulated cyclic nucleotide phosphodiesterase from Neurospora crassa. Biochim Biophys Acta 758:84–87

    Article  PubMed  CAS  Google Scholar 

  • Osmani AH, Osmani SA, Morris NR (1990) The molecular cloning and identification of a gene product specifically required for nuclear movement in Aspergillus nidulans. J Cell Biol 111:543–551

    Article  PubMed  CAS  Google Scholar 

  • Osmani AH, McGuire SL, Osmani SA (1991) Parallel activation of the nimA and p34cdc 2 cell cycle-regulated protein-kinases is required to initiate mitosis in Aspergillus nidulans. Cell 67:283–291

    Article  PubMed  CAS  Google Scholar 

  • Otto DW, Brown RM (1974) Developmental cytology of the genus Vaucheria 1. Organisation of the vegetative filament. Br Phycol J 9:111–126

    Article  Google Scholar 

  • Pall ML (1981) Adenosine 3′,5′-phosphate in fungi. Microbiol Rev 45:462–480

    PubMed  CAS  Google Scholar 

  • Pall ML, Robertson CK (1986) Cyclic AMP control of hierarchical growth pattern of hyphae in Neurospora crassa. Exp Mycol 10:161–165

    Article  CAS  Google Scholar 

  • Perkins DD, Radford A, Newmeyer D, Bjorkman M (1982) Chromosomal loci of Neurospora crassa. Microbiol Rev 46:426–570

    PubMed  CAS  Google Scholar 

  • Peters AC, Wimpenny JWT, Coombs JP (1987) Oxygen profiles in, and in the agar beneath, colonies of Bacillus cereus, Staphylococcus albus and Escherichia coli. J Gen Microbiol 133:1257–1263

    PubMed  CAS  Google Scholar 

  • Pfennig N (1984) Microbial behaviour in natural environments. In: Kelly DP, Carr NG (eds) The microbe 1984. Cambridge University Press, Cambridge, pp 23–50

    Google Scholar 

  • Picton JM, Steer MW (1983) Evidence for the role of Ca2+ ions in tip extension in pollen tubes. Protoplasma 115:11–17

    Article  CAS  Google Scholar 

  • Pirt SJ (1967) A kinetic study of the mode of growth of surface colonies of bacteria and fungi. J Gen Microbiol 47:181–197

    PubMed  CAS  Google Scholar 

  • Pirt SJ (1975) Principles of microbe and cell cultivation. Blackwell, Oxford, UK

    Google Scholar 

  • Pittinger TH, Atwood KC (1954) The relation of growth rate to nuclear ratio in Neurospora heterokaryons. Genetics 39:987–988

    Google Scholar 

  • Prior SL, Cunliffe BW, Robson GD, Trinci APJ (1993) Multiple isomers of phosphatidyl inositol monophosphate and inositol bis and trisphosphates from filamentous fungi. FEMS Microbiol Lett (in press)

    Google Scholar 

  • Prosser JI (1993) Growth kinetics of mycelial colonies and aggregates of ascomycetes. Mycol Res 97:513–528

    Article  Google Scholar 

  • Prosser JI (1994) Morphology and growth of streptomy-cetes. In: Wellington EM (ed) Streptomyces. Plenum Press, New York (in press)

    Google Scholar 

  • Prosser JI, Tough AJ (1991) Growth mechanisms and growth kinetics of filamentous microorganisms. CRC Crit Rev Biotechnol 10:253–274

    Article  CAS  Google Scholar 

  • Prosser JI, Trinci APJ (1979) A model for hyphal growth and branching. J Gen Microbiol 111:153–164

    PubMed  CAS  Google Scholar 

  • Rasmussen H (1981) Calcium and cAMP as synarchic messengers. Wiley, New York

    Google Scholar 

  • Rasmussen H, Means RL, Lu KP, May GS, Means AR (1990) Characterization and expression of the unique calmodulin gene of Aspergillus nidulans. J Biol Chem 265:13767–13775

    PubMed  CAS  Google Scholar 

  • Read ND, Knight H, Trewavas AJ (1992a) Fluorescence ratio imaging and confocal microscopy of calcium in filamentous fungi. Binary 4:50–52

    Google Scholar 

  • Read ND, Allan WTG, Knight H, Knight MR, Malho R, Russell A, Shacklock PS, Trewavas AJ (1992b) Imaging and measurements of cytosolic free calcium in plant and fungal cells. J Microsc 166:57–86

    Article  CAS  Google Scholar 

  • Reig JA, Tellez-Inon MT, Flawia M, Torres HN (1984) Activation of Neurospora crassa soluble adenylate cyclase by calmodulin. Biochem J 221:541–543

    PubMed  CAS  Google Scholar 

  • Reiss H, Herth W (1979) Calcium gradients in tip growing plant cells visualised by CTC-fluorescence. Planta 146: 615–621

    Article  CAS  Google Scholar 

  • Reiss H, Herth W (1985) Nifedipine-sensitive calcium channels are involved in polar growth of lily pollen tubes. J Cell Sci 76:247–254

    PubMed  CAS  Google Scholar 

  • Reiss HD, Herth W, Nobiling R (1985) Development of membrane- and calcium-gradients during pollen germination of Lilium. Planta 163:84–90

    Article  CAS  Google Scholar 

  • Robinow CF (1963) Observations on cell growth, mitosis and division in the fungus Basidiobolus ranarum. J Cell Biol 17:123–152

    Article  PubMed  CAS  Google Scholar 

  • Robinson PM, Smith JM (1979) Development of cells and hyphae of Geotrichum candidum in chemostat and batch culture. Trans Br Mycol Soc 72:39–47

    Article  Google Scholar 

  • Robson GD, Bell SD, Kuhn PJ, Trinci APJ (1987) Glucose and penicillin concentrations in agar medium below fungal colonies. J Gen Microbiol 133:361–367

    PubMed  CAS  Google Scholar 

  • Robson GD, Kuhn PJ, Trinci APJ (1988) Effects of vali-damycin A on the morphology, growth and sporulation of Rhizoctonia cerealis, Fusarium eulmorum and other fungi. J Gen Microbiol 134:3187–3194

    PubMed  CAS  Google Scholar 

  • Robson GD, Kuhn PJ, Trinci APJ (1989) Effect of vali-damycin A on the inositol content and branching of Rhizoctonia cerealis and other fungi. J Gen Microbiol 135:739–750

    CAS  Google Scholar 

  • Robson GD, Trinci APJ, Wiebe MG, Best LC (1991a) Phosphatidylinositol 4,5-bisphosphate (PIP2) is present in Fusarium graminearum. Mycol Res 95:1082–1084

    Article  CAS  Google Scholar 

  • Robson GD, Wiebe MG, Trinci APJ (1991b) Low calcium concentrations induce increased branching in Fusarium graminearum. Mycol Res 95:561–565

    Article  CAS  Google Scholar 

  • Robson GD, Wiebe MG, Trinci APJ (1991c) Involvement of Ca2+ in the regulation of hyphal extension and branching in Fusarium graminearum A3/5. Exp Mycol 15:263–272

    Article  CAS  Google Scholar 

  • Robson GD, Wiebe MG, Trinci APJ (1991d) Exogenous cAMP and cGMP modulates branching in Fusarium graminearum. J Gen Microbiol 137:963–969

    PubMed  CAS  Google Scholar 

  • Rosen WG (1964) Chemotropism and fine structure of pollen tubes. In: Linkens HF (ed) Pollen physiology and fertilization. North Holland, Amsterdam, pp 159–166

    Google Scholar 

  • Rosenberger RF, Kessel M (1967) Synchrony of nuclear replication in individual hyphae of Aspergillus nidulans. J Bacteriol 94:1464–1469

    PubMed  CAS  Google Scholar 

  • Schaechter M, Maaloe O, Kjeldgaard NO (1958) Dependency on medium and temperature of cell size and chemical composition during balanced growth of Salmonella typhimurium. J Gen Microbiol 19:592–606

    PubMed  CAS  Google Scholar 

  • Schmid J, Harold FM (1988) Dual roles for calcium ions in apical growth of Neurospora crassa. J Gen Microbiol 134:2623–2631

    PubMed  CAS  Google Scholar 

  • Schramm M, Towart R (1985) Modulation of calcium channel function by drugs. Life Sci 37:1843–1860

    Article  PubMed  CAS  Google Scholar 

  • Shatkin AJ, Tatum EL (1961) The relationship of m-inositol to morphology in Neurospora crassa. Am J Bot 48:760–761

    Article  CAS  Google Scholar 

  • Steele GC, Trinci APJ (1975) Morphology and growth kinetics of differentiated and undifferentiated mycelia of Neurospora crassa. J Gen Microbiol 91:362–368

    PubMed  CAS  Google Scholar 

  • Tatum EL, Barratt RW, Cutter VM (1949) Chemical induction of colonial paramorphs in Neurospora and Syncephalastrum. Science 109:509–511

    Article  PubMed  CAS  Google Scholar 

  • Tellez-Inon M, Ulloa RM, Glikin GC, Torres HN (1985) Characterization of Neurospora crassa cyclic AMP phosphodiesterase activated by calmodulin. Biochem J 232:425–430

    PubMed  CAS  Google Scholar 

  • Terenzi HF, Flawia MM, Tellez-Inon MT, Torres HN (1976) Control of Neurospora crassa morphology by cyclic adenosine 3′,5′ monophosphate and dibutyryl cyclic adenosine 3′,5′ monophosphate. J Bacteriol 126:41–49

    Google Scholar 

  • Tomes C, Moreno S (1990) Phosphodiesterase activity and cyclic AMP content during early germination of Mucor rouxii spores. Exp Mycol 14:78–83

    Article  CAS  Google Scholar 

  • Trinci APJ (1969) A kinetic study of the growth of Aspergillus nidulans and other fungi. J Gen Microbiol 57:11–24

    PubMed  CAS  Google Scholar 

  • Trinci APJ (1971) Influence of the peripheral growth zone on the radial growth rate of fungal colonies. J Gen Microbiol 67:325–344

    Google Scholar 

  • Trinci APJ (1973) The hyphal growth unit of wild type and spreading colonial mutants of Neurospora crassa. Arch Mikrobiol 91:127–136

    Article  PubMed  CAS  Google Scholar 

  • Trinci APJ (1974) A study of the kinetics of hyphal extension and branch initiation of fungal mycelia. J Gen Microbiol 81:225–236

    PubMed  CAS  Google Scholar 

  • Trinci APJ (1978) The duplication cycle and vegetative development in moulds. In: Smith JE, Berry DR (eds) The filamentous fungi, vol III. Edward Arnold, London, pp 132–163

    Google Scholar 

  • Trinci APJ (1979) The duplication cycle and branching. In: Burnett JJ, Trinci APJ (eds) Fungal walls and hyphal growth. 2nd Symp British Mycological Society. Cambridge University Press, Cambridge, pp 319–358

    Google Scholar 

  • Trinci APJ (1984) Regulation of hyphal branching and hyphal orientation. In: Jennings DH, Rayner ADM (eds) Ecology and physiology of the fungal mycelium. 8th Symp British Mycological Society. Cambridge University Press, Cambridge, pp 23–52

    Google Scholar 

  • Trinci APJ, Banbury GH (1969) Effect of light on growth and carotenogenesis of the tall conidiophores of Aspergillus giganteus. Trans Br Mycol Soc 52:73–86

    Article  CAS  Google Scholar 

  • Trinci APJ, Collinge A J (1973) Influence of L-sorbose on the growth and morphology of Neurospora crassa. J Gen Microbiol 78:179–192

    PubMed  CAS  Google Scholar 

  • Trinci APJ, Thurston CF (1976) Transition to the non-growing state in eukaryotic microorganisms. In: Post-gate JR, Gray TRG (eds) The survival of vegetative microbes. 26th Symp Society for General Microbiology, Cambridge, Cambridge University Press, pp 50–80

    Google Scholar 

  • Tropschug M, Barthelmess I, Neupert W (1989) Sensitivity to cyclosporin A is mediated by cyclophilin in Neurospora crassa and Saccharomyces cerevisiae. Nature 342:953–955

    Article  PubMed  CAS  Google Scholar 

  • Ulloa RM, Torres HN, Ochatt CM, Tellez-Inon MT (1991) Ca2+ calmodulin-dependent protein kinase activity in the ascomycetes Neurospora crassa. Mol Cell Biochem 102:155–163

    Article  PubMed  CAS  Google Scholar 

  • A Vaughan (1993) Growth and morphology of Fusarium graminearum. PhD Thesis, University of Manchester

    Google Scholar 

  • Vermeulen CA, Wessels JGH (1983) Evidence for a phospholipid requirement of chitin synthase in Schizophyllum commune. Curr Microbiol 8:67–71

    Article  CAS  Google Scholar 

  • Wakae O, Matsuura K (1975) Characteristics of validamy-cin as a fungicide for Rhizoctonia disease control. Rev Plant Prot Res 8:81–92

    CAS  Google Scholar 

  • Wiebe MG, Robson GD, Trinci APJ (1990) Edifenphos (Hinosan) reduces hyphal extension, hyphal growth unit length and phosphatidylcholine content of Fusarium graminearum A3/5, but has no effect on specific growth rate. J Gen Microbiol 136:979–984

    CAS  Google Scholar 

  • Wiebe MG, Robson GD, Trinci APJ, Oliver SG (1992) Characterisation of morphological mutants generated spontaneously in glucose-limited continuous flow cultures of Fusarium graminearum A3/5. Mycol Res 96: 555–562

    Article  CAS  Google Scholar 

  • Wilson RW, Niederpruem DJ (1967) Cellobiose as a paramorphogen in Schizophyllum commune. Can J Microbiol 16:629–634

    Article  Google Scholar 

  • Withers JM, Wiebe MG, Robson GD, Trinci APJ (1994) Development of morphological heterogeneity in glucose-limited chemostat cultures of Aspergillus oryzae. Mycol Res 98:95–100

    Article  Google Scholar 

  • Yang H, King R, Reichl U, Gilles ED (1992) Mathematical model for apical growth, septation and branching of mycelial micro-organisms. Biotechnol Bioeng 39:49–58

    Article  PubMed  CAS  Google Scholar 

  • Yarden O, Piamann M, Ebbole DJ, Yanofsky C (1992) cot-1, a gene required for hyphal elongation in Neurospora crassa, encodes a protein kinase. Embo J 11: 2159–2166

    PubMed  CAS  Google Scholar 

  • Yuan S, Heath IB (1991) Chlortetracycline staining patterns of growing hyphal tips of the oomycete Saprolegnia ferax. Exp Mycol 15:91–102

    Article  Google Scholar 

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  1. School of Biological Sciences, 1.800 Stopford Building, Oxford Road, Manchester, M13 9PT, UK

    A. P. J. Trinci, M. G. Wiebe & G. D. Robson

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  1. Department of Plant Biology, University of Groningen, Kerklaan 30, NL-9751 NN, Haren, The Netherlands

    Joseph G. H. Wessels

  2. Institut für Mikrobiologie, Universität Münster, Corrensstraße 3, D-48149, Münster, Germany

    Friedhelm Meinhardt

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© 1994 Springer-Verlag Berlin Heidelberg

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Trinci, A.P.J., Wiebe, M.G., Robson, G.D. (1994). The Mycelium as an Integrated Entity. In: Wessels, J.G.H., Meinhardt, F. (eds) Growth, Differentiation and Sexuality. The Mycota, vol 1. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-11908-2_10

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  • DOI: https://doi.org/10.1007/978-3-662-11908-2_10

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-11910-5

  • Online ISBN: 978-3-662-11908-2

  • eBook Packages: Springer Book Archive

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