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Topische Dermatokosmetika

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Book cover Dermatokosmetik
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Zusammenfassung

Hautpflege hat in der modernen, westlichen Gesellschaft eine extrem große Bedeutung erlangt, und ein gepflegtes Aussehen spielt eine immer wichtiger werdende Rolle. Für wenige andere Industrieprodukte wird heute so viel Geld ausgegeben wie für die individuelle Hautreinigung und -pflege. Viele Menschen empfinden durch die regelmäßige Anwendung von Hautpflegeprodukten eine subjektive Erhöhung ihres Wohlbefindens, ganz im Sinne der Weltgesundheitsorganisation (WHO)-Definition für „Gesundheit“ vom 22.07. 1946: „Gesundheit ist der Zustand des völligen körperlichen, geistigen und sozialen Wohlbefindens und nicht nur das Freisein von Krankheit und Gebrechen”. Zudem konnten Studien belegen, dass Individuen mit einem attraktiveren Äußeren distinkte soziale Vorteile (sowohl privat als auch im Beruf) gegenüber subjektiv als weniger attraktiv empfundenen Menschen haben [2, 29, 78, 80]. Dies trifft in gewissem Umfang auch für ältere Menschen zu, die sich ein jüngeres Aussehen erhalten haben. Eine andere Untersuchung konnte z. B. zeigen, dass Menschen ohne Akne eine größere Chance haben, eine berufliche Anstellung zu finden als Aknepatienten [36]. Eine Reihe von Studien zeigten auf, dass dermatokosmetische Verfahren helfen können, einige der Vorteile, die physisch attraktivere und jünger aussehende Menschen genießen, zu erlangen [63, 78, 80].

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Literatur

  1. Abdulghani AA, Sherr A, Shirin S et al (1998) Effects of topical creams containing vitamin C, a copper-binding peptide cream and melatonin compared with tretinoin on the ultrastructure of normal skin. DMCO 1: 136–141

    Google Scholar 

  2. Adams GR, Huston TL (1975) Social perception of middle-aged persons varying in physical attractiveness. Dev Psychol 11: 657–658

    Article  Google Scholar 

  3. Artmann C, Röding J, Ghyczy M, Pratzel HG (1990) Influence of various liposome preparations on skin humidity. Parfümerie Kosmetik 5: 326–327

    Google Scholar 

  4. Baran R, Maibach HI (eds) (2002) Textbook of Cosmetic Dermatology (2nd edn) Martin Dunitz, London, 1998

    Google Scholar 

  5. Bässler KH, Golly I, Loew D, Pietrzik K (2002) Vitamin Lexikon, 3. Aufl. Urban and Fischer Verlag, München Jena

    Google Scholar 

  6. Baulieu EE, Thomas G, Legrain S, Lahlou N, Roger M, Debuire B, Faucounau V, Girard L, Hervy MP, Latour F, Leaud MC, Mokrane A, Pitti-Ferrandi H, Trivalle C, de Lacharriere O, Nouveau S, Rakoto-Arison B, Souberbielle JC, Raison J, Le Bouc Y, Raynaud A, Girerd X, Forette F (2000) Dehydroepiandrosterone (DHEA), DHEA sulfate, and aging: contribution of the DHEAge Study to a sociobiomedical issue. Proc Natl Acad Sci USA 97 (8): 4279–4284

    Article  PubMed  CAS  Google Scholar 

  7. Baumann L (2002) Cosmetic Dermatology Principles and Practice. Mc Graw Hill, New York

    Google Scholar 

  8. Bayerl C, Keil D (2002) Isoflavonoide in der Behandlung der Hautalterung postmenopausaler Frauen. Akt Dermatol 28 (S1): 14–18

    Article  Google Scholar 

  9. a.Beitner H (2003) Randomized, placebo-controlled, double blind study on the clinical efficacy of a cream containing 5% alpha lipoic acid related to photoaging of facial skin. Br J Dermatol 149: 841–849

    Article  PubMed  CAS  Google Scholar 

  10. Behler A, Hensen H, Vier J (1996) Kokosmonoglyceridsulfat - ein Aniontensid für kosmetische Formulierungen. Fett/Lipid 98: 09

    Article  Google Scholar 

  11. Bentley JP, Brenner RM, Linstedt AD, West NB, Carlisle KS, Rokosova BC, MacDonald N (1986) Increased hyaluronate and collagen biosynthesis and fibroblast estrogen receptors in macaque sex skin. J Invest Dermatol 87: 668–673

    Article  PubMed  CAS  Google Scholar 

  12. Bernstein EF (2002) Reactive oxygen species activate the human elastin promoter in a trans-genic model of cutaneous photoaging. Dermatol Surg 28: 132–135

    Article  PubMed  Google Scholar 

  13. Bertin C, Sinégre L, Cambon M, Issachar N, Arnaud-Boissel L, Camel E, Robert C, Pellegrino A (2000) A placebo-controlled clinical study assessing the anti-aging effect of the combination dimethylamino ethanol + tyrosine. Posterpräsentation auf dem 20. World Congress of Dermatology, Paris, July 1–5 (Poster)

    Google Scholar 

  14. Bhawan J (1998) Short-and long-term histologic effects of topical tretinoin on photo-damaged skin. Int J Dermatol 37: 286–292

    Article  PubMed  CAS  Google Scholar 

  15. Billek DE (1987) Liposomen und ihre Bedeutung für kosmetische Präparate. SÖFW J 113: 469–473

    CAS  Google Scholar 

  16. Bissett DL, Chatterjee R, Hannon DP (1991) Chronic ultraviolet radiation-induced increase in skin iron and the photoprotective effect of topically applied iron chelators. Photochem Photobiol 54: 215–223

    Article  PubMed  CAS  Google Scholar 

  17. Blatt T, Mundt C, Mummert C, Maksiuk T, Wolber R, Keyhani R, Schreiner V, Hoppe U, Schachtschabel DO, Stäb F (1999) Modulation des oxidatitiven Stresses in der humanen Altershaut. Z Gerontol Geriatr 32: 83–88

    Article  PubMed  CAS  Google Scholar 

  18. Boldyrev AA, Gallant SC, Sukhich GT (1999) Carnosine, the protective, anti-aging peptide. Biosci Rep 19: 581–587

    Article  PubMed  CAS  Google Scholar 

  19. Böni R, Burg G (2000) Altershaut: physiologische Grundlagen, prophylaktische Maßnahmen und Therapieansätze. Schweiz Med Wochenschr 130: 1272–1278

    PubMed  Google Scholar 

  20. Braun-Falco O, Gloor M, Korting HC (Hrsg) (2000) Nutzen und Risiko von Kosmetika. Springer, Berl in Heidelberg

    Google Scholar 

  21. Brenneisen P, Wenk J, Klotz LO, Wlaschek M, Briviba K, Krieg T, Sies H, Scharffetter-Kochanek K (1998) Central role of ferrous/ferric iron in the ultraviolet B irradiation-mediated signaling pathway leading to increased interstitial collagenase (Matrix-degrading Metalloprotease (MMP)-1) and Stromelysin-1 (MMP-3) mRNA levels in cultured human dermal fibroblasts. J Biol Chem 273: 5279–5287

    Article  PubMed  CAS  Google Scholar 

  22. Brincat MP (2000) Hormone replacement therapy and the skin. Maturitas 35: 107–117

    Article  PubMed  CAS  Google Scholar 

  23. Brincat M, Moniz CF, Studd JW, Darby AJ, Magos A, Cooper D (1983) Sex hormones and skin collagen content in postmenopausal women. Br Med J (Clin Res Ed) 287: 1337–1338

    Article  CAS  Google Scholar 

  24. Brincat M, Versi E, O’Dowd T, Moniz CF, Magos A, Kabalan S, Studd JW (1987) Sk in collagen changes in post-menopausal women receiving oestradiol gel. Maturitas 9:1–5

    Google Scholar 

  25. Brown GL, Nanney LB, Griffen J, Cramer AB, Yancey JM, Curtsinger LJ 3rd, Holtzin L, Schultz GS, Jurkiewicz MJ, Lynch JB (1989) Enhancement of wound healing by topical treatment with epidermal growth factor. N Engl J Med 321: 76–79

    Article  PubMed  CAS  Google Scholar 

  26. Busch P (1995) Historische Entwicklung der Kosmetik. In: Umbach W (Hrsg) Kosmetik, 2. Aufl. Georg Thieme Verlag, Stuttgart, S 1–9

    Google Scholar 

  27. Calabrese V, Randazzo SD, Catalano C, Rizza V (1999) Biochemical studies on a novel antioxidant from lemon oil and its biotechnological application in cosmetic dermatology. Drugs Exptl Clin Res 25: 219–225

    CAS  Google Scholar 

  28. Calabrese V, Scapagnini G, Catalano C, Dinotta F, Geraci D, Morganti P (2000) Biochemical studies of a natural antioxidand isolated from rosemary and its application in cosmetic dermatology. Int J Tissue React 22: 5–13

    PubMed  CAS  Google Scholar 

  29. Callens A, Vaillant L, Lecomte P, Berson M, Gall Y, Lorette G (1996) Does hormonal skin aging exist? A study of the influence of different hormone therapy regimens on the skin of postmenopausal women using non-invasive measurement techniques. Dermatology 193: 289–294

    Article  PubMed  CAS  Google Scholar 

  30. Cash TF (1985) Physical appearance and mental health. In: Graham JA, Kligman AM (eds) The psychology of cosmetic treatments. Praeger, New York, pp 196–216

    Google Scholar 

  31. Castelo-Branco C, Duran M, Gonzalez-Merlo J (1992) Skin collagen changes related to age and hormone replacement therapy. Maturitas 15: 113–119

    Article  PubMed  CAS  Google Scholar 

  32. Chan AC (1993) Partners in defense, vitamin E and vitamin C. Can J Physiol Pharmacol 71: 725–731

    Article  CAS  Google Scholar 

  33. Chaudhuri RK (2002) Emblica cascading antioxidant: a novel natural skin care ingredient. Skin Pharmacol Appl Skin Physiol 15: 374–380

    Article  PubMed  CAS  Google Scholar 

  34. Cole CA, Gisoldi EM, Grossman RM (2002) Clinical and consumer evaluations of improved facial appearance after 1 month use of topical dimethylaminoethanol. 60th Annual Meeting of the American Academy of Dermatology, New Orleans, USA, February 22–27 (Poster)

    Google Scholar 

  35. Colven RM, Pinnell SR (1996) Topical Vitamin C in Aging. Clin Dermatol 14: 225–234

    Article  Google Scholar 

  36. Creidi P, Vienne MP, Ochonisky S, Lauze C, Turlier V, La Garde JM, Dupuy P (1998) Profilo-metric evaluation of photodamaged skin after topical retinaldehyde and retinoic acid treatment. J Am Acad Dermatol 13: 525–535

    Google Scholar 

  37. Cunliffe WJ (1986) Acne and unemployment. Br J Dermatol 115: 386

    Article  PubMed  CAS  Google Scholar 

  38. Daniels R (2000) Kosmetische Wirkstoffe. In: Braun-Falco O, Gloor M, Korting HC (Hrsg) Nutzen and Risiko von Kosmetika. Springer, Berlin Heidelberg, S 160–168

    Chapter  Google Scholar 

  39. Darr D, Combs S, Dunston S, Manning T, Pinnell S (1992) Topical vitamin C protects porcine skin from ultraviolet radiation-induced damage. Br J Dermatol 127: 47–53

    Article  Google Scholar 

  40. Dissemond J, Goos M, Wagner SN (2002) Die Bedeutung von oxidativem Stress in der Genese and Therapie chronischer Wunden. Hautarzt 53: 718–723

    Article  PubMed  CAS  Google Scholar 

  41. Draelos ZD (2000) Therapeutic moisturizers. Dermatol Clin 18: 597–607

    Article  PubMed  CAS  Google Scholar 

  42. Dreher F, Gabard B, Schwindt DA, Maibach HI (1998) Topical melatonin in combination with vitamins E and C protects skin from ultraviolet-induced erythema: a human study in vivo. Br J Dermatol 139: 332–339

    CAS  Google Scholar 

  43. Driller H (1996) Verbesserte Wirkung durch Nanoemulsionen. In: Ziolkowski B (Hrsg) Kosmetikjahrbuch. Verlag für Chem Industrie, Augsburg, S 272–277

    Google Scholar 

  44. Elmets CA, Singh D, Tubesing K, Matsui M, Katiyar S, Mukhtar H (2001) Cutaneous photoprotection from ultraviolet injury by green tea phenols. J Am Acad Dermatol 44: 425–432

    Article  PubMed  CAS  Google Scholar 

  45. Fisher GJ, Wang TQ, Datta SC, Varani J, Kang S, Voorhees JJ (1997) Pathophysiology of premature skin aging induced by ultraviolet light. N Engl J Med 337: 1419–1428

    Article  PubMed  CAS  Google Scholar 

  46. Fisher GJ, Voorhees JJ (1998) Molecular mechanisms of photoaging and its prevention by retinoic acid: ultraviolet irradiation induces MAP kinase signal transduction cascades that induce AP-1-regulated matrix metalloproteinases that degrade human skin in vivo. J Invest Dermatol Symp Proc 3: 61–68

    Article  CAS  Google Scholar 

  47. a.Fitzpatrick RE, Rostan EF (2003) Reversal of photodamage with topical growth factors. J Cosmetic Laser Ther 5: 25–34

    Article  Google Scholar 

  48. Francès C (1998). Smoker’s wrinkles: epidemiological and pathogenic considerations. Clin Dermatol 16: 565–570

    Article  PubMed  Google Scholar 

  49. Fresta M, Puglisi G (1996) Application of liposomes as potential cutaneous drug delivery systems. In vitro and in vivo investigations with radioactively labelled vesicles. J Drug Target 4: 95–101

    Article  PubMed  CAS  Google Scholar 

  50. Friedland JA, Buchel EW (2000) Skin care and the topical treatment for aging skin. Clin Plast Surg 27 (4): 501–506

    PubMed  CAS  Google Scholar 

  51. Fujimura T, Tsukahara K, Moriwaki S, Kitahara T, Sano T, Takema Y (2002) Treatment of human skin with an extract of Fucus vesiculosus changes its thickness and mechanical properties. J Cosmet Sci 53: 1–9

    PubMed  Google Scholar 

  52. Gallarate M, Charlotti ME, Trotta M, Bovo S (1998) On the stability of ascorbic acid in emulsified systems for topical and cosmetic use. Int J Pharm, 188: 233–241

    Article  Google Scholar 

  53. Gareiß, J, Hoff E, Ghyczy M (1994) Phospholipide–Liposomen–Nanoemulsionen. Parfümerie Kosmetik; 10: 652–659

    Google Scholar 

  54. Gareiß J, Hoff E, Ghyczy M (1995) Phospholipide - Liposomen - Nanoemulsionen. II. Effekte auf der Haut. Parfümerie Kosmetik 152: 152155

    Google Scholar 

  55. Gey KF (1998) Vitamins E plus C and interacting conutrients required for optimal health. A critical and constructive review of epidemiology and supplementation data regarding cardiovascular disease and cancer. Biofactors 7: 113–174

    CAS  Google Scholar 

  56. Ghyczy M, Gareiss J, Kovats T (1994) Liposomes from vegetable phosphatidylcholine. Their production and effects on the skin. Cosmet Toiletries 109: 75–80

    Google Scholar 

  57. Gloor M (2000) Emulgatoren und Emulsionen. In: Braun-Falco O, Gloor M, Korting HC (Hrsg) Nutzen und Risiko von Kosmetika. Springer, Berlin Heidelberg, S 146–153

    Chapter  Google Scholar 

  58. Gloor M, Gehring W (2003) Eigenwirkungen von Emulsionen auf die Hornschichtbarriere und -hydratation. Hautarzt 54: 324–330

    PubMed  CAS  Google Scholar 

  59. Gloor M, Schermer St, Gehring W (1997) Ist eine Kombination von Harnstoff und Glycerin in Externagrundlagen sinnvoll? Z Hautkr 72: 585–590

    Google Scholar 

  60. Goldfarb MT, Ellis CN, Weis JS, Voorhees JJ (1989) Topical tretinoin therapy: its use in photoaged skin. J Am Acad Dermatol 21: 645650

    Google Scholar 

  61. Griffiths CE, Russman, AN, Majmudar G, Singer RS, Hamilton TA, Voorhees JJ (1993) Restauration of collagen formation in photodamaged huma skin by tretinoin (retinoic acid). N Eng J Med 329: 530–535

    Article  CAS  Google Scholar 

  62. Griffiths CE, Kang S, Ellis CN, Kim KJ, Finkel LJ, Ortiz-Ferrer LC, White GM, Hamilton TA, Voorhees JJ (1995) Two concentrations of topical tretinoin [retinoic acid) cause similar improvement of photoaging but different degrees of irritation. A double-blind, vehicle-controlled comparison of 0.1% and 0.025% tretinoin creams. Arch Dermatol 131: 1037–1044

    Article  PubMed  CAS  Google Scholar 

  63. Grosman N, Hvidberg E, Schou J (1971) The effect of oestrogenic treatment on the acid muco-polysaccharide pattern in skin of mice. Acta Pharmacol Toxicol (Copenh) 30: 458–464

    Article  CAS  Google Scholar 

  64. Grossman RM, Gisoldi EM, Cole CA (2002) Long term safety and efficacy evaluation of a new skin firming technology: dimethylaminoethanol. 60th Annual Meeting of the American Academy of Dermatology. New Orleans, USA, February 22–27 (Poster)

    Google Scholar 

  65. Gupta MA, Schork NJ, Ellis CN (1993) Psychosocial correlates of the treatment of photo-damaged skin with topical retinoic acid: a prospective controlled study. J Am Acad Dermatol 30: 969–972

    Article  Google Scholar 

  66. Henry F, Pierard-Franchimont C, Cauwenbergh G, Pierard G (1997) Age-related changes in facial skin contours and rheology. J Am Geriatr Soc 45: 220–222

    PubMed  CAS  Google Scholar 

  67. Hill K, Rhode O (1999) Carbohydrate-based surfactants. Fett/Lipid 101: 25

    Article  CAS  Google Scholar 

  68. Hipkiss A (1998) Carnosine, a protective, anti-ageing peptide? Int J Biochem Cell Biol 30: 863868

    Google Scholar 

  69. Hönigsmann H (2002) Einfluss einer Hormonersatz-Therapie auf die Hautalterung. Akt Dermatol 28 (S1): 10–13

    Article  Google Scholar 

  70. Hoppe U, Bergemann J, Diembeck W, Ennen J, Gohla S Harris I, Jacob J, Kielholz J, Mei W, Pollet D, Schachtschnabel D, Sauermann G, Schreiner V, Stab F, Steckel F (1999) Coenzyme Q10, a cutaneous antioxidant and energizer. Biofacts 9: 371–378

    Article  CAS  Google Scholar 

  71. Hoppe U, Sauermann G, Diembeck W, Ennen J, Hillemann Th, Schreiner V, Stäb F, Kielholz J, Gohla S, Jacob J (1999) Coenzyme Q10–a cutaneous antioxidant and energizer. Kosmetische Medizin 20: 22–26

    Google Scholar 

  72. Junginger HE, Hofland HEJ, Bouwstra JA (1991) Liposomen und Niosomen-Herstellung und Prüfung. Pharm Z 136: 1631–1641

    Google Scholar 

  73. Kang S, Duell EA, Fisher GJ, Datta SC, Wang ZQ, Reddy AP, Tavakkol A, Yi JY, Griffiths CE, Elder JT et al (1995) Application of retinol to human skin in vivo induces epidermal hyperplasia and cellular retinoid binding proteins characteristic of retinoic acid but without measurable retinoic acid levels or irritation. J Invest Dermatol 105: 549–556

    Article  PubMed  CAS  Google Scholar 

  74. Kästner W (1989) Vitamin E: Absicherung bei der Verwendung in Externa. Fat Sci Technol 91: 305–312

    Google Scholar 

  75. Katiyar SK, Mukhtar H (2001) Green tea poly-phenol (-)-epigallocatechin-3-gallate treatment to mouse skin prevents UVB-induced infiltration of leukocytes, depletion of antigen-presenting cells, and oxidative stress. J Leukoc Biol 69: 719–726

    PubMed  CAS  Google Scholar 

  76. Katayama K, Armendariz-Borunda J, Raghow R et al (1993) A pentapeptide from type I procollagen promotes extracellular matrix production. J Biol Chem 268: 9941–9944

    PubMed  CAS  Google Scholar 

  77. Kitazawa M, Iwasaki K (1999) Reduction of ultraviolet light-induced oxidative stress by amino acid-based iron chelators. Biochim Biophys Acta 1473: 400–408

    Article  PubMed  CAS  Google Scholar 

  78. Kligman AM (1957) Dermatologic uses of urea. Acta Dermatol Venereol 37: 155–159

    CAS  Google Scholar 

  79. Kligman AM (1978) Regression method for assessing the efficacy of moisturizers. Cosm Toilietr 93: 27–35

    Google Scholar 

  80. Kligman AM (1998) The myth of lanolin allergy. Contact Dermatitis 39: 103–107

    Article  PubMed  CAS  Google Scholar 

  81. Kligman AM, Graham JA (1989) The psychology of appearance in the elderly. Clin Geriatr Med 5: 213–222

    PubMed  CAS  Google Scholar 

  82. Kligman AM, Grove GL, Hirose R, Leyden JJ (1986) Topical tretinoin for photoaged skin. J Am Acad Dermatol 15: 836–859

    Article  PubMed  CAS  Google Scholar 

  83. Koblenzer CS (1996) Psychologic aspects of aging and the skin. Clin Dermatol 14: 171–177

    Article  PubMed  CAS  Google Scholar 

  84. Korting HC (2003) Differenzierte Galenik bei trockener Haut. Mittagsseminar der Vichy Laboratories. 42. Tagung der Deutschen Dermatologischen Gesellschaft, Berlin

    Google Scholar 

  85. Kreyden OP, Borradori L, Truch RM, Burg G, Nestle FO (2001) Successful therapy with tetracycline and nicotinamide in cicatricial pemphigoid. Hautarzt 52: 247–250

    Article  PubMed  CAS  Google Scholar 

  86. Krüger N, Fiegert L, Becker D, Reuther T, Kerscher M (2003) Zur Behandlung der Hautalterung: Spurenelemente in Form eines Kupfertripeptidkomplexes. Kos Med 24: 31–33

    Google Scholar 

  87. b.Lahmann C, Bergemann J, Harrison G, Young AR (2001) Matrix metalloproteinase-1 and skin ageing in smokers. Lancet 357: 935–936

    Google Scholar 

  88. Lehmann L, Keipert S, Gloor M (2001) Effect of microemulsions on the stratum corneum and hydrocortisone penetration. Eur J Pharm Biopharm 52: 129–136

    Article  PubMed  CAS  Google Scholar 

  89. Leyden JJ, Grove G, Stephens TJ, Finkey MB, Barkovic BA, Appa Y (2002) Skin benefits of copper peptide containing eye creams. 60th Annual Meeting of the American Adademy of Dermatology. New Orleans, USA, February 22–27

    Google Scholar 

  90. Leyden JJ, Grove G, Chen T, Appa Y (2002) Immediate and continuing effects of DMAE on face and neck: a split-face study. 60th Annual Meeting of the American Adademy of Dermatology. New Orleans, USA, February 22–27 (Poster)

    Google Scholar 

  91. a.Lintner K (2002) Promoting production in the extracellular matrix without compromising barrier. Cutis (Suppl) 70 (6S): 13–16

    Google Scholar 

  92. Lopez-Torres M, Thiele JJ, Shindo Y, Han D, Packer L (1998) Topical application of alpha-tocopherol modulates the antioxidant network and diminishes ultraviolet-induced oxidative damage in murine skin. Br J Dermatol 138: 207–215

    Article  PubMed  CAS  Google Scholar 

  93. Malvy J, Guinot C, Preziosi P, Vaillant L, Tenenhaus M, Galan P, Hercberg S, Tschachler E (2000) Epidemiologic determinants of skin photoaging: baseline data of the SU.VI.MAX. cohort. J Am Acad Dermatol 42: 47–55

    Article  PubMed  CAS  Google Scholar 

  94. Man MQ, Feingold KR, Elias PM (1993) Exogenous lipids influence permeability barrier recovery in acetone-treated murine skin. Arch Dermatol 129: 728–738

    Article  PubMed  CAS  Google Scholar 

  95. Maquart FX, Pickart L, Laurent M, Gillery P, Monboisse JC, Borel JP (1988) Stimulation of collagen synthesis in fibroblast cultures by the tripeptide-copper complex glycyl L histidyl L lysine CuZ+. FEBS Lett 238: 343–346

    Article  PubMed  CAS  Google Scholar 

  96. Maquart FX, Bellon G, Chaqour B, Wegrowski J, Patt LM, Trachy RE, Monboisse JC, Chastang F, Birembaut P, Gillery P et al (1993) In vivo stimulation of connective tissue accumulation by the tripeptide-copper complex glycyl-L-histidyl-Llysine-Cu2 in rat experimental wounds. J Clin Invest 92: 2368–2376

    Article  PubMed  CAS  Google Scholar 

  97. Martine MC, Bobin MF (1984) Role des micro-émulsions dans 1-absorption percutanée de l’alpha-tocophérole. J Pharm Belg 39: 348–354

    Google Scholar 

  98. Masaki H, Sakaki S, Atsumi T, Sakurai H (1995) Active-oxygen scavenging activity of plant extracts. Biol Pharm Bull 18: 162–166

    Article  PubMed  CAS  Google Scholar 

  99. Mayer P, Pittermann W, Wallat S (1993) The effects of vitamin E on the skin. Cosmet Toiletries 108: 99–109

    CAS  Google Scholar 

  100. McFarland GA, Holliday R (1999) Further evidence for the rejuvenating effects of the dipetide L-carnosine on cultured human diploid fibroblast. Exp Gerontol 34: 35–45

    Article  PubMed  CAS  Google Scholar 

  101. Merck KGaA Darmstadt (2001) http://www. merckeurolab.ltd.uk/corporate/press_release/ Ronacare.htm.

    Google Scholar 

  102. Merck KGaA Darmstadt (2001) http://me.merck. de/EMD/UK/UKNEWS.NSF/…

    Google Scholar 

  103. Mitani H, Koshiishi I, Sumita T, Imanari T (2001) Prevention of the photodamage in the hairless mouse dorsal skin by kojic acid as an iron chelator. Eur J Pharmacol 411: 169–174

    Article  PubMed  CAS  Google Scholar 

  104. Willer A, Ansmann A, Wallat S (1989) Wirkungen von Vitamin E auf die Haut bei topischer Anwendung. Fat Sci Technol 91: 295305

    Google Scholar 

  105. Müller RH, Dingler A (1986) The next generation after the liposomes: solid lipid nano particles (SLN®, LipopearlsTM) as dermal carrier in cosmetics. Eurocosmetics 1998, 7 /8: 19–26

    Google Scholar 

  106. Nagai K, Suda T, Kawasaki K, Mathuura S (1986) Action of carnosine and beta-alanine on wound healing. Surgery 100: 815–821

    PubMed  CAS  Google Scholar 

  107. Nusgens BV, Humbert P, Rougier A, Colige AC, Haftek M, Lambert CA, Richard A, Creidi P, Lapiere CM (2001) Topically applied vitaminC enhances the mRNA level of collagen I and III, their processing enzymes and tissue inhibitors of matrix metalloproteinase 1 in the human dermis. J Invest Dermatol 116: 853–859

    Article  PubMed  CAS  Google Scholar 

  108. Oddos T, Jumeau-Lafond A, Ries G (2002) Requirement of copper tripeptide glycyl-L-histidyl-L-lysine (GHK) complex formation for collagen synthesis activity in normal human dermal fibroblasts. 60th Annual Meeting of the American Adademy of Dermatology. New Orleans, USA, February 22–27 (Poster)

    Google Scholar 

  109. Olsen EA, Katz HI, Levine N, Shupack J, Billys MM, Prawer S, Gold J, Stiller M, Lufrano L, Thorne EG (1992) Tretinoin emollient cream: a new therapy for photodamaged skin. Am Acad Dermatol 1: 215–224

    Article  Google Scholar 

  110. Olsen EA, Katz HI, Levine N, Nigra P, Pochi PE, Savin RC, Shupack J, Weinstein GD, Lufrano L, Perry BH (1997) Tretinoin emollient cream for photodamaged skin: Results of 48-week, multicenter, double-blind studies. Am Acad Dermatol 2: 218–230

    Google Scholar 

  111. Parnham MJ (2000) Neuartige Vehikelbestandteile. In: Braun-Falco O, Gloor M, Korting HC (Hrsg) Nutzen and Risiko von Kosmetika. Springer, Berlin Heidelberg, S 131–136

    Chapter  Google Scholar 

  112. Pinnell SR (2003) Cutaneous photodamage, oxidative stress, and topical antioxidant pretection. J Am Acad Dermatol 48: 1–19

    Article  PubMed  Google Scholar 

  113. Ponec M, Weerheim A, Kempenaar J, Mulder AA, Gooris GS, Bouwstra J, Mommas AM (1997) The formation of competent barrier lipids in reconstructed human epidermis requires the presence of vitamine C. J Invest Dermatol 109: 348–355

    Article  PubMed  CAS  Google Scholar 

  114. Pourzand C, Watkin RD, Brown JE, Tyrrell RM (1999) Ultraviolet A radiation induces immediate release of iron in human primary skin fibroblasts: the role of ferritin. Proc Natl Acad Sci USA 96: 6751–6756

    Article  PubMed  CAS  Google Scholar 

  115. Proserpio G (1978) Lanolides: emollients or moisturizers? Cosmet Toilet 93: 45–48

    CAS  Google Scholar 

  116. Punnonen R, Vaajalahti P, Teisala K (1987) Local oestriol treatment improves the structure of elastic fibers in the skin of postmenopausal women. Ann Chir Gynaecol (Suppl) 202: 39–41

    CAS  Google Scholar 

  117. Quan T, He T, Kang S, Voorhees JJ, Fisher GJ ((2002) Ultraviolet irradiation alters transforming growth factor beta/smad pathway in human skin in vivo. J Invest Dermatol 119: 499–506

    Google Scholar 

  118. Quinn PJ, Boldyrev AA, Formazuyk VE (1992) Carnosine: its properties, functions and potential therapeutic applications. Mol Aspects Med 13: 379–444

    Article  PubMed  CAS  Google Scholar 

  119. Rawlings AV, Davies A, Carlomusto M, Pillai S, Zhang K, Kosturko R, Verdejo P, Feinberg C, Nguyen L, Chandar P (1996) Effect of lactic acid isomers on keratinocyte ceramide synthesis, stratum corneum lipid levels and stratum corneum barrier function. Arch Dermatol Res 288: 383–390

    Article  PubMed  CAS  Google Scholar 

  120. Reeve VE, Bosnic M, Rozinova E (1993) Carnosine (beta-alanylhistidine) protects from the suppression of contact hypersensitivity by ultraviolet B (280–320 nm) radiation or by cis urocanic acid. Immunology 78: 99–104

    PubMed  CAS  Google Scholar 

  121. Ricciarelli R (1999) Age-dependent increase of collagenase expression can be reduced by alpha-tocopherol via protein kinase C inhibition. Free Radic Biol Med 27: 729–737

    Article  PubMed  CAS  Google Scholar 

  122. Rice-Evans C, Miller NJ, Paganda G (1996) Structure-antioxidant activity relationship of flavonoids and phenolic acids. Free Radical Biol Med 20: 933–956

    Article  CAS  Google Scholar 

  123. Sander CS, Chang H, Salzmann S, Müller CS, Ekanayake-Mudiyans S, Elsner P, Thiele JJ (2002) Photoaging is associated with protein oxidation in human skin in vivo. J Invest Dermatol 118: 618–625

    Article  PubMed  CAS  Google Scholar 

  124. Sator PG, Schmidt JB, Sator MO, Huber JC, Honigsmann H (2001) The influence of hormone replacement therapy on skin ageing: a pilot study. Maturitas 39: 43–55

    Article  PubMed  CAS  Google Scholar 

  125. Scharffetter-Kochanek K, Wlaschek M, Brenneisen P, Schauen M, Blaudschun R, Wenk J (1997) UV-induced reactive oxygen species in photocarcinogenesis and photoaging. Biol Chem 378: 1247–1257

    PubMed  CAS  Google Scholar 

  126. Schmidt JB, Binder M, Demschik G, Bieglmayer C, Reiner A (1996) Treatment of skin aging with topical estrogens. Int J Dermatol 35: 669–674

    Article  PubMed  CAS  Google Scholar 

  127. Schöffling U (2002) Biokompatible Emulsionssysteme. „Hightech“ and „Bio” im Cremetopf. Sonderdruck aus Derma Forum

    Google Scholar 

  128. Schröder JM (2001) Primary defense factors of human skin. Defensines and other antimicrobial peptides. Med Report

    Google Scholar 

  129. Sendagorta E, Lesiewicz J, Armstrong RB (1992) Topical isotretinoin for photodamaged skin. J Am Acad Dermatol 6: S15–18

    Article  Google Scholar 

  130. Shindo Y, Witt E, Han D, Epstein W, Packer L (1994) Enzymatic and non-enzymatic antioxidants in epidermis and dermis of human skin. J Invest Dermatol 102: 122–124

    Article  PubMed  CAS  Google Scholar 

  131. Sigler ML, Stephens TJ, Barkovic BA, Finkey MS, Appa Y (2002) A clinical evaluation of a copper-peptide-containing liquid foundation and cream concealer designed for improving skin condition. 60th Annual Meeting of the American Academy of Dermatology. New Orleans, USA, February 22–27 (Poster)

    Google Scholar 

  132. Simeon A, Wegrowski Y, Bontemps Y, Maquart FX (2000) Expression of glycosaminoglycans and small proteoglycans in wounds: modulation by the tripeptide-copper complex glycyl-L-histidyl-L-lysine-Cu(2+). J Invest Dermatol 115: 962–968

    Article  PubMed  CAS  Google Scholar 

  133. Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273: 59–63

    Article  PubMed  CAS  Google Scholar 

  134. Soriani M, Rice-Evans C, Tyrrell RM (1998) Modulation of the UVA activation of haem oxygenase, collagenase and cyclooxygenase gene expression by epigallocatechin in human skin cells. FEBS Letters 439: 253–257

    Article  PubMed  CAS  Google Scholar 

  135. Spuitt D (1971) The interference of some substances with the water vapor loss of human skin. Dermatologica 142: 89–92

    Article  Google Scholar 

  136. Stege H, Roza L, Vink AA, Grewe M, Ruzicka T, Grether-Beck S, Krutmann J (2000) Enzyme plus light therapy to repair DNA-damage in ultraviolet-B-irradiated human skin. Proc Natl Acad Sci USA 97: 1790–1795

    Article  PubMed  CAS  Google Scholar 

  137. Strasburger CJ, Jaursch-Hancke C, Kann PH, Klingmüller D, Plöckinger U, Petersenn S, Quabbe HJ (2002) Missbräuchlicher Einsatz von humanem Wachstumshormon in der AntiAging-Medizin. Dtsch Arztebl 99 (Hef- t 47): A3177–3180

    Google Scholar 

  138. Streyer L (1990) Biochemie, 3. Aufl. Spektrum der Wissenschaft Verlagsgesellschaft, Heidelberg

    Google Scholar 

  139. Tanaka H, Okada T, Konishi H, Tsuji T (1993) The effect of reactive oxygen species on the biosynthesis of collagen and glycosaminoglycans in cultured human dermal fibroblasts. Arch Dermatol Res 285: 352–355

    Article  PubMed  CAS  Google Scholar 

  140. Thiele JJ, Schröter C, Hsieh SN, Podda M, Packer L (2001) The antioxidant network of the stratum corneum. Curr Probl Dermatol 29: 26–42

    Article  PubMed  CAS  Google Scholar 

  141. Traikovich SS (1999) Use of topical ascorbic acid and its effects on photodamaged skin topography. Arch Otolaryngol Head Neck Surg 125: 1091–1098

    PubMed  CAS  Google Scholar 

  142. Varani J, Warner RL, Gharaee-Kermani M, Phan SH, Kang S, Chung JH, Wang ZQ, Fisher GJ, Vorhees JJ (2000) Vitamin A antagonizes decreased cell growth and elevated collagen-degrading matrix metalloproteinases and stimulates collagen accumulation in naturally aged human skin. J Invest Dermatol 114: 480486

    Google Scholar 

  143. Vile GF, Tyrrell RM (1995) UVA radiation-induced oxidative damage to lipids and proteins in vitro and in human skin fibroblasts is dependent on iron and singlet oxygen. Free Radic Biol Med 18: 721–730

    Article  PubMed  CAS  Google Scholar 

  144. Vile GF, Basu-Modak S, Waltner C, Tyrrell RM (1994) Heme oxygenase 1 mediates an adaptive response to oxidative stress in human skin fibroblasts. Proc Natl Acad Sci USA 91: 26072610

    Google Scholar 

  145. Wallo W, Kollias N, Payonk G, Kurtz ES (2002) Clinical instrumental documentation of the skin firming effects of topical dimethylaminoethanol. 60th Annual Meeting of the American Academy of Dermatology. New Orleans, USA, February 22–27 (Poster)

    Google Scholar 

  146. Wegrowski Y, Maquart FX, Borel JP (1992) Stimulation of sulfated glycosaminoglycan synthesis by the tripeptide-copper complex glycylL-histidyl-L-lysine-Cu2+. Life Sci 51: 1049–1056

    Article  PubMed  CAS  Google Scholar 

  147. Wehr RF, Krochmal L (1987) Considerations in selecting a moisturizer. Cutis 39: 512–515

    PubMed  CAS  Google Scholar 

  148. Wenk J, Foitzik A, Achterberg V, Sabiwalsky A, Dissemond J, Meewes C, Reitz A, Brenneisen P, Wlaschek M, Meyer-Ingold W, ScharffetterKochanek K (2001) Selective pick-up of increased iron by deferoxamine-coupled cellulose abrogates the iron-driven induction of matrix-degrading metalloproteinase 1 and lipid peroxidation in human dermal fibroblasts in vitro: a new dressing concept. J Invest Dermatol 116: 833–839

    Article  PubMed  CAS  Google Scholar 

  149. Werninghaus K, Meydani M, Bhawan J, Margolis R, Blumberg JB, Gilchrest BA (1994) Evaluation of the photoprotective effect of oral vitamin E supplementation. Arch Dermatol 130: 12571261

    Google Scholar 

  150. Wie Z, Zhang X, Zhao JF, Wang ZY, Bickers D, Lebwohl M (1999) Scavenging of hydrogen peroxide and inhibition of ultraviolet light-induced oxidative DNA damage by aqueous extracts form green tea. Free Radic Biol Med 26: 1427–1435

    Article  Google Scholar 

  151. Whitten PL, Patisaul HB (2001) Cross-species and interassay comparisons of phytoestrogen action. Environ Health Perspect 109 (Suppl): 520

    Google Scholar 

  152. Wlaschek M, Tantcheva-Poor I, Naderi L, Ma W, Schneider LA, Razi-Wolf Z, Schuller J, Scharfetter-Kochanek K (2001) Solar UV irradiation and dermal photoaging. J Photochem Photobiol B 63: 41–51

    Article  PubMed  CAS  Google Scholar 

  153. Wohlrab W (1990) Effect of urea on penetration kinetics of vitamin A acid in human skin. Z Hautkr 65: 803–805

    PubMed  CAS  Google Scholar 

  154. Wolber R, Keyhani R, Stäb F, Hoppe U, Schachtschabel DO (1997) Aktiver Zellschutz durch topische Applikation von Antioxidanzien. In: Schütz RM, Ries W, Tews HP (Hrsg) Altern in Gesundheit und Krankheit. BiblioMed-Medizinische Verlagsgesellschaft MWH, Melsungen, S 235–249

    Google Scholar 

  155. Wolf R, Wolf D, Ruocco V (1998) Vitamin E: the radical protector. J Eur Acad Dermatol Venereol 10: 103–117

    Article  PubMed  CAS  Google Scholar 

  156. Yarosh D, Klein J, O’Conner A, Hawk J, Rafal E, Wolf P (2001) Effect of topically applied T4 endonuclease V in liposome on skin cancer in xeroderma pigmentosum: a randomised study. Xeroderma pigmentosum study group. Lancet 24: 926–929

    Google Scholar 

  157. Zatz JL (1993) Modification of skin permeation by surface active agents. In: Zatz JL (Hrsg) Skin permeation. Fundamentals and application. Allured, Wheaton, pp 149–162

    Google Scholar 

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Kerscher, M. (2004). Topische Dermatokosmetika. In: Dermatokosmetik. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-11456-8_6

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