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The Value of Estimating Pressure-volume Index in Childhood Macrocephaly

  • R. H. J. M. Gooskens
  • C. C. A. M. Gielen
  • J. Willemse

Abstract

Most of the information on cerebrospinal fluid (CSF) dynamics is obtained by CSF infusion. The most important variables of CSF dynamics are resistance to absorption or outflow resistance (Ro) and compliance of the CSF spaces. Since pressure varies exponentially as a function of volume, compliance changes with pressure. If the logarithm of CSF pressure is plotted against CSF volume, a linear relationship is formed. The slope of the resulting straight line is defined as the pressure-volume index (PVI).

Key words

Cerebrospinal fluid dynamics Pressure volume index Intracranial volume 

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • R. H. J. M. Gooskens
    • 1
  • C. C. A. M. Gielen
    • 2
  • J. Willemse
    • 1
  1. 1.Departments of Child NeurologyUniversity of UtrechtHeidelberglaan, UtrechtThe Netherlands
  2. 2.Departments of Medical PhysicsUniversity of UtrechtHeidelberglaan, UtrechtThe Netherlands

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