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Histochemical Study of Acetylcholinesterase Activity in the Hippocampus of Rats with Kaolin-induced Hydrocephalus: A preliminary report

  • Masato Nagasaka
  • Hiroji Kuchiwaki
  • Junki Itoh
  • Sohshun Takada
  • Hitoshi Ishiguri
  • Takehisa Kinomoto
  • Naoki Kageyama

Abstract

It is well known that dementia is one of the major symptoms of the patients with “normal pressure hydrocephalus (NPH).” However, the pathogenesis of the symptom has not fully been understood. Many scientific contributions have appeared on the recently proposed “cholinergic hypothesis of geriatric memory dysfunction.”

Key words

Normal pressure hydrocephalus Dementia Kaolin-induced hydrocephalus Septo-hippocampal projection Acetylcholinesterase 

Copyright information

© Springer-Verlag Berlin Heidelberg 1990

Authors and Affiliations

  • Masato Nagasaka
    • 1
  • Hiroji Kuchiwaki
    • 1
  • Junki Itoh
    • 1
  • Sohshun Takada
    • 1
  • Hitoshi Ishiguri
    • 1
  • Takehisa Kinomoto
    • 1
  • Naoki Kageyama
    • 1
  1. 1.Department of NeurosurgeryNagoya University School of MedicineNagoyaJapan

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