Abstract
We studied the morphological development and cytogenesis of the telencephalic choroid plexus in the rat from embryonic day 13 (E13) to 20. Cell proliferation was investigated with bromodeoxyuridine (BrdU), an analogue of thymidine. Based on the results of preliminary studies on the cytotoxic effects of BrdU and the appropriate dose for immunohistochemical detection, 20 mg/kg of BrdU was injected intraperitoneally to each pregnant rat. Fetuses were removed respectively 1 and 4 hours after the injection, and BrdU-incorporated nuclei were demonstrated by the avidine-biotin peroxidase complex method.
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© 1989 Springer-Verlag Berlin Heidelberg
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Yamada, M., Yoshida, Y., Wakabayashi, K., Ikuta, F. (1989). Growth Pattern of the Telencephalic Choroid Plexus of Rat Embryo. In: Matsumoto, S., Sato, K., Tamaki, N., Oi, S. (eds) Annual Review of Hydrocephalus. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-11149-9_5
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DOI: https://doi.org/10.1007/978-3-662-11149-9_5
Publisher Name: Springer, Berlin, Heidelberg
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