Zusammenfassung
Frühgeborene und wachstumsverzögerte Neugeborene benötigen eine Versorgung durch darauf spezialisierte Kinderkrankenschwestern und -ärzte,auch wenn eine Intensivtherapie nicht oder anfangs noch nicht notwendig erscheint. Das folgende Kapitel gibt eine Einführung in einige wichtige Aspekte der Therapie. Frühgeborene benötigen neben Sauerstoff vor allem Wärme, Flüssigkeit und Nahrung. Diese Feststellung mag simpel erscheinen,aber der tatsächliche diesbezügliche Bedarf wurde quantitativ und qualitativ erst in den vergangenen drei Jahrzehnten eingehender untersucht. Entsprechend lückenhaft sind nach wie vor unsere Kenntnisse. Ergänzungen und Korrekturen sind in rascher Folge zu erwarten. Die genaue Beachtung dieses Wissensstandes bei der Therapie ist für solche Kinder potenziell von lebenslanger Bedeutung, da unsere Behandlung wahrscheinlich in die Zeitfenster verschiedener früher biologischer Prägungsphasen fällt.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Literatur
American Academy of Pediatrics Committee on Nutrition (1985) Nutritional needs of low-birth-weight infants. Pediatrics 75: 976–986
AMWF (1997) Leitlinie: antepartaler Transport von Risiko-Schwangeren. Perinat Med 9: 68
Arbuckle TE, Wilkens R, Sherman GJ (1993) Birth weight percentiles by gestational age in Canada. Obstet Gynecol 81: 39–48
Asanuma H,Numazaki K, Nagata N, HotsuboT, Horino K, Chiba S (1996) Role of milk whey in the transmission of human cytomegalovirus infection by breast milk.Microbiol Immunol40:201–204
Bell EF (1995) Treatment of sick newborns in incubators. In: Okken A, Koch J (eds) Thermoregulation of sick and low birth weight neonates. Springer, Berlin Heidelberg New York, pp 143–149
Bell EF, Warburton D, Stonestreet BS, Oh W (1980) Effect of fluid administration on the development of symptomatic patent ductus arteriosus and congestive heart failure in premature infants. N Engl J Med 302: 598–604
Bernecker M, Pokorny D, Brisch KH, Pohlandt F (2000) Morbidität von Frühgeborenen im ersten Jahr and Zufriedenheit der Eltern nach früher Entlassung aus dem Krankenhaus. Monatsschr Kinderheilkd 148: 1079–1086
Brooten D, Kumar SP, Brown LP et al. (1986) A randomized clinical trial of early hospital discharge and home follow-up of very-lowbirth-weight infants. N Engl J Med 15: 934–938
Bursztein S (1991) Oxygen cost of breathing during weaning. Intensive Care Med 17: 193–194
Campbell MK (1991) Assessment of regionalized perinatal programs. J Dev Physiol 15: 125–131
Campbell S, Warsof SL, Little D, Cooper DJ (1985) Routine ultrasound screening for the prediction of gestational age. Obstet Gynecol 65: 613–620
Casiro OG, McKenzie ME, McFadyen L et al. (1993) Earlier discharge with community-based intervention for low birth weight infants:a randomized trial. Pediatrics 92: 128–134
CMA Committee on Nutrition (1995) Nutrient needs and feeding of premature infants. Can Med Assoc J 152: 1765–1785
Conde-Agudelo A, Diaz-Rosello JL, Belizan JM (2000) Kangaroo mother care to reduce morbidity and mortality in low birthweight infants.Cochrane Neonatal Review
Cornblath M, Hawdon JM, Williams AF, Aynsley-Green A, Ward-Platt MP, Schwartz R, Kalhan SC (2000) Controversies regarding definition of neonatal hypoglycemia: suggested operational thresholds. Pediatrics 105: 1141–1145
Cowett RM (1999) Neonatal hypoglycemia:a little goes a long way.J Pediatr 134: 389–391
Crouse DT, Cassady G (1994) The small-for-gestational-age infant. In: Avery GB, Fletcher MA, MacDonald MG (eds) Neonatology: pathophysiology and management of the newborn. JB Lippincott, Philadelphia, pp 369–398
Darnall RA, Kattwinkel J, Nattie C, Robinson M (1997) Margin of safety for discharge after apnea in preterm infants. Pediatrics 100: 795–801
DGGG, DGKJ, DGPM, GNPI (1998) Frühgeburt an der Grenze der Lebensfähigkeit des Kindes. Frauenarzt 39: 1803–1805
Ferrannini E (1988) The theoretical bases of indirect calorimetry: a review. Metabolism 37: 287–301
Fierson WM (1997) Screening examination of premature infants for retinopathy of prematurity. Pediatrics 100: 273–273
Franz AR, Mihatsch WA, Sander S, Kron M, Pohlandt F (2000) Prospective randomized trial of early versus late enteral iron supplementation in infants with a birth weight of less than 1301 grams. Pediatrics 106: 700–706
Friel JK, Andrews WL, Matthew JD, Long DR, Cornel AM, Cox M, Skinner CT (1990) Iron status of very-low-birth-weight infants during the first 15 months of infancy. CMAJ 143: 733–737
Geirsson RT, Busby-Earle RM (1991) Certain dates may not provide a reliable estimate of gestational age. Br J Obstet Gynaecol 98: 108–109
Glass L, Silverman WA, Sinclair JC (1968) Effect of the thermal environment on cold resistance and growth of small infants after the first week of life. Pediatrics 41: 1034–1046
Guyton AC (1991) Dietary balances; regulation of feeding; obesity and starvation; Vitamins and minerals. In: Guyton AC (ed) Textbook of medical physiology. WB Saunders Company, Philadelphia London Toronto Montreal Sydney, pp 777–796
Halamek LP, Stevenson DK (1998) Neonatal hypoglycemia, part II: Pathophysiology and therapy. Clin Pediatr 37: 11–16
Hamprecht K, Maschmann J, Vochem M, Dietz K, Speer CP, Jahn G (2001) Epidemiology of transmission of cytomegalovirus from mother to preterm infant by breastfeeding. Lancet 357: 513–518
Hawdon JM, Kalhan SC, Ward Platt MP, Cornblath M (1999) Clinical features of neonates with hyperinsulinism. N Engl J Med 341: 701–702
Hawdon JM, Ward Platt MP, Aynsley-Green A (1992) Patterns of metabolic adaptation for preterm and term infants in the first neonatal week. Arch Dis Child 67: 357–365
Kalhan S, Peter-Wohl S (2000) Hypoglycemia: what is it for the neonate? Am J Perinatol 17: 11–18
Kalhan SC, Raghavan CV (1998) Metabolism of glucose in the fetus and newborn. In: Polin RA, Fox WW (ed) Fetal and neonatal physiology.WB Saunders, Philadelphia, PA, pp 543–558
Kotagal UR, Perlstein PH, Gamblian V, Donovan EF, Atherton HD (1995) Description and evaluation of a program for the early discharge of infants from a neonatal intensive care unit. J Pediatr 127: 285–290
Kuschel CA, Harding JE (2002) Protein supplementation of human milk for promoting growth in preterm infants (Cochrane Review).The Cochrane Library, vol 1, Oxford
Light RB (1988) Intrapulmonary oxygen consumption in experimen- tal pneumococcal pneumonia.J Appl Physiol 64: 2490–2495
Lubchenco LO, Hansman C, Dressler M, Boyd E (1963) Intrauterine growth as estimated from liveborn birth-weight data at 24 to 42 weeks gestation. Pediatrics 32: 793–800
Lucas A, Bishop NJ, King FJ,ColeTJ (1992) Randomised trial of nutrition for preterm infants after discharge. Arch Dis Child 67: 324–327
Lundstrom U, Siimes MA, Dallman PR (1977) At what age does iron supplementation become necessary in low-birth-weight infants? J Pediatr 91: 878–883
Marconi AM, Paolini C, Buscaglia M, Zerbe G, Battaglia FC, Pardi G (1996) The impact of gestational age and fetal growth on the maternal-fetal glucose concentration difference. Obstet Gynecol 7: 937–942
Maschmann J, Hamprecht K, Dietz K, Jahn G, Speer CP (2001) Cytomegalovirus infection of extremely low-birth weight infants via breast milk. CID 33: 1998–2003
Maschmann J, Speer CP, Jahn G, Hamprecht K (1999) Inactivation of cytomegalovirus in breast milk. Pediatr Res 45: 924A
McDonald MC, Abrams SA, Schanler RJ (1998) Iron absorption and red blood cell incorporation in premature infants fed an iron-fortified infant formula. Pediatr Res 44: 507–511
McIntosh N, Wilmshurst A, Hailey J (1995) Experiences with thermal monitoring, influence of neonatal care and how should it be monitored. In: Okken A, Koch J (eds) Thermoregulation of sick and low birth weight neonates. Springer, Berlin Heidelberg New York, pp 69–82
Meredith HV (1970) Body weight at birth of viable human infants: a worldwide comparative treatise. Hum Biol 42: 217–264
Micheli JL, Schutz Y (1993) Protein. In: Tsang RC, Lucas A, Uauy R, Zlotkin S (eds) Nutritional needs of the preterm infant. Scientific basis and practical guidelines. Williams & Wilkins, Baltimore, pp 29–46
Micheli JL, Schutz Y, Pfister R, Laubscher B, Calame A, Jéquier E (1993) Fluid requirements, water balance, and metabolism in low birth weight infants. In: Salle BL, Swyer PR (eds) Nutrition of the low birth weight infant, vol 32. Nestec, Vevey/Raven Press, New York, pp 43–59
Monset-Couchard M, Bethmann Ode (2000) Catch-up growth in 166 small for gestational age premature infants weighing less than 1,000 g at birth. Biol Neonate 78: 161–167
Nunn JF (1996) Pulmonary oxygen consumption. Intensive Care Med 22: 275–276
Pierro A, Carnielli V, Filler RM, Kicak L, Smith J, Heim TF (1991) Partition of energy metabolism in the surgical newborn. J Pediatr Surg 26: 581–586
Puckett RM, Offringa M (2000) Prophylactic vitamin K for vitamin K deficiency bleeding in neonates. Cochrane Neonatal Review
Putet G (1993) Energy. In: Tsang RC, Lucas A, Uauy R, Zlotkin S (eds) Nutritional needs of the preterm infant: scientific basis and practical guidelines. Williams & Wilkins, Baltimore, pp 15–28
Ragosch V, Ebert AD, Hundertmark S (2001) Die imminente Frühgeburt als Notfall. Gynäkologe 34: 739–743
Ramasethu J, Gunter KC, McClenny RP, Luban NLC, Fletcher AB (1997) When is iron supplementation appropriate for the extremely low birth weight infant? Pediatr Res 41: 239A
Reichman BL, Chessex P, Putet G, Verellen GJ, Smith JM, Heim T, Swyer PR (1982) Partition of energy metabolism and energy cost of growth in the very low-birth-weight infant. Pediatrics 69: 446–451
Rey, Martinez H (1983) Rational management of the premature infant. Curso de medicina fetal y neonatal, Bogotà, Colombia, pp 137–151
Rieger-Fackeldey E, Genzel-Boroviczeny O, Schulze A (2000) Schwere systemische Zytomegalievirusinfektion bei zwei extrem unreifen Frühgeborenen über die Muttermilch. Z Geburtsh NeonatoI204: S52–553
Sanders M, Allen M, Alexander GR,Yankowitz J, Graeber J, Johnson TR, Repka MX (1991) Gestational age assessment in preterm neonates weighing less than 1500 grams. Pediatrics 88: 542–546
Sanderson DA, Wilcox MA, Johnson IR (1994a) The individualised birthweight ratio: a new method of identifying intrauterine growth retardation. Br J Obstet Gynaecol 101: 310–314
Sanderson DA, Wilcox MA, Johnson IR (1994b) Relative macrosomia identified by the individualised birthweight ratio (IBR). A better method of identifying the at risk fetus. Acta Obstet Gynecol Scand 73: 246–249
Schellscheidt J, Oyen N, Jorch G (1997) Interactions between maternal smoking and other prenatal risk factors for sudden infant death syndrome ( SIDS ). Acta Paediatr 86: 857–863
Schulze A, Abubakar K, Gill G, Way RC, Sinclair JC (2001) Pulmonary oxygen consumption: a hypothesis to explain the increase in oxygen consumption of low birth weight infants with lung disease. Intensive Care Med 27: 1636–1642
Scopes JW, Ahmed I (1966) Range of critical temperatures in sick and premature newborn babies. Arch Dis Child 41: 417–419
Sinclair JC (1995) Effect of the thermal environment on neonatal mortality and morbidity: state of the evidence. In: Okken A, Koch J (eds) Thermoregulation of sick and low birth weight neonates. Springer, Berlin Heidelberg New York, pp 127–141
Sinclair JC (1997) Approaches to the definition of neonatal hypoglycemia. Acta Paediatr Japonica 39 (Suppl 1): 517–520
Staubach F, Lagrèze WA (2002) Frühgeborenenretinopathie. Monatsschr Kinderheilkd 150: 302–308
Swenne I, Ewald U, Gustafsson J, Sandberg F, Ostenson C (1994) Inter-relationship between serum concentrations of glucose, glucagon and insulin during the first two days of life in healthy newborns. Acta Paediatr 83: 915–919
Vochem M, Hamprecht K, Jahn G, Speer CP (1997) Zytomegalievirusinfektionen von Frühgeborenen über die Muttermilch. Monatsschr Kinderheilkd 145: 619–625
Vochem M, Hamprecht K, Jahn G, Speer CP (1998) Transmission of cytomegalovirus to preterm infants through breast milk. Pediatr Infect Dis J 17: 53–58
Wauben IP, Atkinson SA, Shah JK, Paes B (1998) Growth and body composition of preterm infants: influence of nutrient fortification of mother’s milk in hospital and breastfeeding post-hospital discharge. Acta Paediatr 87: 1–6
Weller U, Jorch G (1993) Aktuelle Perzentilenkurven für Körpergewicht, Körperlänge and Kopfumfang von Neugeborenen ab 25 SSW. Monatsschr Kinderheilkd 141: 665–669
WHO (1998) The World Health Report 1998. Life in the 21st century: a vision for all. World Health Organization, Geneva
Widdowson EM (1968) Growth and composition of the fetus and newborn. Biol of Gestation 2: 1–49
Wilcox MA, Johnson IR, Maynard PV, Smith SJ, Chilvers CE (1993) The individualised birthweight ratio: a more logical outcome measure of pregnancy than birthweight alone. Br J Obstet Gynaecol 100: 342–347
Yeast JD, Poskin M, Stockbauer JW, Shaffer S (1998) Changing patterns in regionalization of perinatal care and the impact on neonatal mortality. Am J Obstet Gynecol 178: 131–135
Zlotkin SH, Bryan MH, Anderson GH (1981) Intravenous nitrogen and energy intakes required to duplicate in utero nitrogen accretion in prematurely born human infants. J Pediatr 99: 115120
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2004 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Schulze, A. (2004). Frühgeborene und hypotrophe Neugeborene. In: Reinhardt, D. (eds) Therapie der Krankheiten im Kindes- und Jugendalter. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10471-2_6
Download citation
DOI: https://doi.org/10.1007/978-3-662-10471-2_6
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-662-10472-9
Online ISBN: 978-3-662-10471-2
eBook Packages: Springer Book Archive