Cell-Mediated Immunity

  • Juneann W. Murphy
Part of the The Mycota book series (MYCOTA, volume 6)


CMI responses are key host protective responses against mycotic agents. Thus, to comprehend fully the means by which fungal pathogens are eliminated from the body, it is important to understand thoroughly the interactions of the cells with cell-produced soluble factors (cytokines) that are involved in the CMI response directed against the specific fungal pathogen. Like all immune responses, any given CMI response must be induced in the host by the specific organism before it is functional. This means that if the host has not previously encountered the specific fungus, then the host will not have memory T cells directed toward that organism and will not display a specific CMI response against that fungal agent. However, upon first entry of the organism into the body, the immunocompetent host generally develops a CMI response directed against the fungus.


Cryptococcus Neoformans Cryptococcal Antigen Chronic Mucocutaneous Candidiasis Candida Antigen Mucosal Candidiasis 
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Copyright information

© Springer-Verlag Berlin Heidelberg 1996

Authors and Affiliations

  • Juneann W. Murphy
    • 1
  1. 1.Department of Microbiology and ImmunologyUniversity of Oklahoma Health Sciences CenterOklahoma CityUSA

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