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Ubiquitin-Dependent Proteolysis by the Proteasome

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The Molecular Biology of Schizosaccharomyces pombe

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Abstract

Ubiquitin-dependent proteolysis via the 26S proteasome is a major mechanism for the specific regulation of protein levels within the eukaryotic cell. It has been shown to mediate the regulated destruction of a wide range of proteins including cell cycle regulators, tumour suppressors, transcription factors and misfolded or damaged proteins (Voges et al. 1999).

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Authors
  1. Miranda Stone
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  2. Colin Gordon
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Editors and Affiliations

  1. Department of Genetics, Institute of Molecular Biology, University of Copenhagen, Øster Farimagsgade 2A, 1353, Copenhagen K, Denmark

    Richard Egel

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© 2004 Springer-Verlag Berlin Heidelberg

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Stone, M., Gordon, C. (2004). Ubiquitin-Dependent Proteolysis by the Proteasome. In: Egel, R. (eds) The Molecular Biology of Schizosaccharomyces pombe . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10360-9_25

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  • DOI: https://doi.org/10.1007/978-3-662-10360-9_25

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-05631-4

  • Online ISBN: 978-3-662-10360-9

  • eBook Packages: Springer Book Archive

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