Abstract
The concept of protein-coding gene regulation at the level of transcription involves the interplay between activators and repressors, which in turn allow or prevent the DNA-dependent RNA polymerase to transcribe the structural gene. Usually activators or repressors bind as proteins to DNA sequences upstream of the coding region. This basic paradigm has been discovered in prokaryotes; as organisms evolved, however, mechanisms became increasingly complex (Huang et al. 1999).
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Witt, I., Kivinen, K., Käufer, N.F. (2004). Core Promoters in S. pombe: TATA and HomolD Boxes. In: Egel, R. (eds) The Molecular Biology of Schizosaccharomyces pombe . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-10360-9_22
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DOI: https://doi.org/10.1007/978-3-662-10360-9_22
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-05631-4
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