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Zelluläre und subzelluläre Funktionen der vitalen Organe bei Sepsis und Multiorganversagen

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Sepsis

Zusammenfassung

Die Probleme, die bei invasiver, massiver oder unkontrollierter Infektion entstehen, können für den chirurgischen Patienten deletär sein. Trotz Asepsis, Antisepsis, sorgfältiger chirurgischer Technik und Antibiotika stellt die Infektion immer noch eine Plage für uns und unsere Patienten dar. Wenn der Prozeß nicht durch Abwehrmechanismen, Drainagen oder Antibiotika unter Kontrolle gebracht werden kann, stellt sich bei einem Individuum mit Sepsis eine charakteristische Folge von Störungen der Zirkulation, der Organfunktion und des Metabolismus ein. Es existiert ein einheitlicher metabolischer Einfluß der Infektion, der in Qualität und Quantität allein von der Verletzung abhängig ist. Die Ausdrücke „Sepsis“ und „septisch“ werden i. allg. bei Patienten mit einem septischen Hauptherd wie generalisierter Peritonitis, einem intraperitonealen Abszeß, einem Leberabszeß, einem Lungenempyem, Lungenentzündung, schwerer Zellulitis, Gewebeischämie mit Infektion oder anderen Prozessen, die mit Nekrose und Invasion pathogener Organismen einhergehen, benutzt.

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Authors
  1. A. E. Baue
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  1. Universitätsklinikum Steglitz Klinik für Anästhesiologie und operative Intensivmedizin, Freie Universität Berlin, Hindenburgdamm 30, D-1000, Berlin 45, Deutschland

    K. Reinhart  & K. Eyrich  & 

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Baue, A.E. (1989). Zelluläre und subzelluläre Funktionen der vitalen Organe bei Sepsis und Multiorganversagen. In: Reinhart, K., Eyrich, K. (eds) Sepsis. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09869-1_16

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  • DOI: https://doi.org/10.1007/978-3-662-09869-1_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-09870-7

  • Online ISBN: 978-3-662-09869-1

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