Abstract
In two ways, disturbed sleep is likely to indicate a condition of increased pathophysiologic vulnerability in patients with cardiovascular risk factors or clinical manifestation of cardiovascular disease. First, advanced cardiovascular pathophysiology can be seen as a relevant cause of disturbed sleep. It is well known that pain associated with nocturnal unstable angina provokes awakenings, and similar experiences happen in patients with severe peripheral artery occlusion. Poor sleep is often reported in patients with congestive heart failure and may be present in other cardiovascular syndromes. Second, disturbed sleep by itself may promote cardiovascular dysfunction and contribute to the development of breakdown in adaptive responses of the cardiovascular system to internal or external demands. The present contribution focuses on the second approach. After a brief examination of the epidemiologically established link between disturbed sleep and cardiovascular morbidity and mortality two arguments are presented in more detail. The first concentrates on the role of sleep apnea as a risk factor for near-future ischemic heart disease (IHD) whereas the second argument defines distrubed sleep in the framework of chronic social stress which by now is a widely accepted precipitating factor in the development of overt IHD.
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© 1989 Springer-Verlag Berlin Heidelberg
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Siegrist, J. (1989). Sleep disturbances in pre-infarction patients. In: v. Arnim, T., Maseri, A. (eds) Predisposing Conditions for Acute Ischemic Syndromes. Steinkopff, Heidelberg. https://doi.org/10.1007/978-3-662-09434-1_5
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DOI: https://doi.org/10.1007/978-3-662-09434-1_5
Publisher Name: Steinkopff, Heidelberg
Print ISBN: 978-3-662-09436-5
Online ISBN: 978-3-662-09434-1
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