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Endokrinologie

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Physiologie des Menschen

Part of the book series: Springer-Lehrbuch ((SLB))

Zusammenfassung

Der Göttinger Physiologe A. A. Berthold publizierte 1848 Experimente, die den Beginn der modernen Hormonforschung darstellen. Es war seit langem bekannt, daß Hähne nach Kastration den geschwollenen Hahnenkamm verlieren und weniger aggressives Verhalten zeigen. Zu Bertholds Zeiten wurde angenommen, daß Hoden und ZNS auf nervalem Wege kommunizieren. Berthold kastrierte Hähne und reimplantierte die Hoden in die Bauchhöhle. Der Hahnenkamm blieb geschwollen und die Tiere zeigten weiterhin aggressives Dominanzverhalten. Damit war der Beweis erbracht, daß ein oder mehrere humorale Signale von den Testes zum ZNS gelangen. Noch heute werden Hormonwirkungen durch ähnliche experimentelle Ansätze getestet: Hormonproduzierende Organe werden entfernt und die Ausfallserscheinungen untersucht. Wird das Hormon schließlich substituiert und die Ausfallserscheinungen unterbleiben oder bilden sich zurück, ist der Beweis erbracht, daß es sich um eine hormonelle Wirkung handelt.

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Literatur

Weiterführende Lehr- und Handbücher

  1. Besser GM, Rees LH (1985) The pituitary-adrenocortical axis. Saunders, Philadelphia (Clinics in endocrinology and metabolism, vol 14/4)

    Google Scholar 

  2. Franchimont P (1986) Paracrine contr. Saunders, Philadelphia (Clinics in endocrinology and metabolism, vol 15/1)

    Google Scholar 

  3. Guyton AC (1986) Textbook of medical physiology, 7th edn. Saunders, Philadelphia

    Google Scholar 

  4. Hakanson R, Thorell J (1985) Biogenetics of neurohormonal peptides. Academic, New York

    Google Scholar 

  5. Johnson M, Everitt B (1980) Essential reproduction. Blackwell Scientific, Oxford

    Google Scholar 

  6. Johnston DG, Alberti KGMM (1982) New aspects of diabetes. Saunders, Philadelphia (Clinics in endocrinology and metabolism, vol 11/2)

    Google Scholar 

  7. Jungermann K, Möhler H (1980) Biochemie. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  8. Knobil E, Neill JD (1993) The physiology of reproduction. Raven, New York

    Google Scholar 

  9. Krieger DT, Brownstein MJ, Martin JB (1983) Brain peptides. Wiley, New York

    Google Scholar 

  10. Leyendecker G, Stock H, Wildt L (1983) Brain and pituitary peptides II. Pulsatile administration of Gn-RH in hypothalamic failure: basic and clinical aspects. Karger, Basel

    Google Scholar 

  11. Martini L, James VHT (1983) The endocrinology of pregnancy and parturition. Academic, New York (Experimental endocrinology, vol 3 )

    Google Scholar 

  12. Robinson GA, Butcher RW, Sutherland EW (1971) Cyclic AMP. Academic, New York

    Google Scholar 

  13. Shearman RP (1985) Clinical reproductive endocrinology. Churchill Livingstone, Edinburgh

    Google Scholar 

  14. Toft AD (1985) Hyperthyroidism. Saunders, Philadelphia (Clinics in endocrinology and metabolism, vol 14/2)

    Google Scholar 

  15. Wilson JD, Foster DW (1985) William’s textbook of endocrinology,7th edn. Saunders, Philadelphia

    Google Scholar 

  16. Wuttke W, Weindl A, Voigt KH, Dries R-R (198o) Brain and pituitary peptides. Karger, Basel

    Google Scholar 

  17. Wuttke W, Horowski R (1981) Gonadal steroids and brain function. Springer, Berlin Heidelberg New York

    Book  Google Scholar 

  18. Yen SSC, Jaffe RB (1986) Reproductive endocrinology. Saunders, Philadelphia

    Google Scholar 

Einzel- and Übersichtsarbeiten

  1. Adashi EY (1990) The potential relevance of cytokines to ovarian physiology: the emerging role of resident ovarian cells of the white blood cell series. Endocr Rev 11:454–464

    Google Scholar 

  2. Brommage R, DeLuca HF (1985) Evidence that 1,25-dihy-droxy-vitamin D3 is the physiologically active metabolite of vitamin D3. Endocr Rev 6 /4: 491–511

    Article  PubMed  CAS  Google Scholar 

  3. Brownstein MJ, Russell JT, Gainer H (1982) Biosynthesis of posterior pituitary hormones. Front Neuroendocrinol 7:31–43

    Google Scholar 

  4. Canalis E (1983) The hormonal and local regulation of bone formation. Endocr Rev 4 /1: 62–77

    Article  PubMed  CAS  Google Scholar 

  5. Cantin M, Genest J (1985) The heart and the atrial natriuretic factor. Endocr Rev 6 /2: 107–127

    Article  PubMed  CAS  Google Scholar 

  6. DeLuca HF (1981) Recent advances in the metabolism of vitamin D. Annu Rev Physiol 44: 141–162

    Google Scholar 

  7. Eipper BA, Mains RE (1980) Structure and biosynthesis of pro-adrenocorticotropin/endorphin and related peptides. Endocr Rev 1 /1: 1–27

    Article  PubMed  CAS  Google Scholar 

  8. Espey L (1980) Ovulation an inflammatory reaction - a hypothesis. Biol Reprod 22: 73

    Article  PubMed  CAS  Google Scholar 

  9. Froesch ER,Schmid C,SchwanderJ,ZapfJ (1985) Actions of insulin-like growth factors.Annu Rev Physiol 47:443-467

    Google Scholar 

  10. Guillemin R (1978) Peptides in the brain: the new endocrinology of the neuron (Nobel lecture). Science 202: 390–402

    Article  PubMed  CAS  Google Scholar 

  11. Habener JF (1981) Regulation of parathyroid hormone secretion and biosynthesis. Annu Rev Physiol 43: 211–223

    Article  PubMed  CAS  Google Scholar 

  12. Herbert E, Roberts J, Phillips M, Allen R, Hinman M, Bu-darf M, Policastro P, Rosa P (1980) Biosynthesis, processing, and release of corticotropin, ß-endorphin, and melanocyte-stimulating hormone in pituitary cell culture systems. Front Neuroendocrinol 6:67-sot

    Google Scholar 

  13. Hughes JP, Friesen HG (1985) The nature and regulation of the receptors for pituitary growth hormone. Annu Rev Physiol 47:469–482

    Google Scholar 

  14. Imura H, Nakai Y (1981),,Endorphins“ in pituitary and other tissues. Annu Rev Physiol 43: 265–278

    Google Scholar 

  15. Isaksson OGP, Eden S, Jansson J-O (1985) Mode of action of pituitary growth hormone on target cells. Annu Rev Physiol 47483–499

    Google Scholar 

  16. Jacobson DH, Gorman CA (1984) Endocrine ophthalmopathy: current ideas concerning etiology, pathogenesis, and treatment. Endocr Rev 5 /2: 200–220

    Article  PubMed  CAS  Google Scholar 

  17. Jaffe RB, Monroe SE (198o) Hormone interaction and regulation during the menstrual cycle. Front Neuroendocrinol 6:219-247

    Google Scholar 

  18. Jensen EV, Greene GL, Gloss LE, DeSombre ER, Nadji M (1982) Receptors reconsidered: a 20-year perspective. Academic, New York, pp 1–4o (Recent progress in hormone research, vol 38 )

    Google Scholar 

  19. Keller-Wood ME, Dallman MF (1984) Corticosteroid inhibition of ACTH secretion. Endocr Rev 5 /1: 1–24

    Article  PubMed  CAS  Google Scholar 

  20. Knobil E (1980) Neuroendocrine control of the menstrual cycle. Recent Prog Horm Res 36: 53–88

    PubMed  CAS  Google Scholar 

  21. Kotchen TA, Guthrie GP (1980) Renin-angiotensin-aldosterone and hypertension. Endocr Rev 1 /1: 78–99

    Article  PubMed  CAS  Google Scholar 

  22. Lenzen S, Bailey CJ (1984) Thyroid hormones, gonadal and adrenocortical steroids and the function of the islets of Langerhans. Endocr Rev 5/3411–434

    Google Scholar 

  23. Leong DA, Frawley LS, Neill JD (1983) Neuroendocrine control of prolactin secretion. Annu Rev Physiol 45: 109–127

    Article  PubMed  CAS  Google Scholar 

  24. Leong DA, Frawley LS, Neill JD (1983) Neuroendocrine control of prolactin secretion. Annu Rev Physiol 45: 109–127

    Article  PubMed  CAS  Google Scholar 

  25. McEwen BS, Biegon A, Davis PG, Krey LC, Luine VN, McGinnis MY, Paden CM, Parsons B, Rainbow TC (1982) Steroid hormones: humoral signals which alter brain cell properties and functions. Recent Prog Horm Res 38: 41–92

    PubMed  CAS  Google Scholar 

  26. Melmed S, Braunstein GD, Horvath E, Ezrin C, Kovacs K (1983) Pathophysiology of acromegaly. Endocr Rev 4 /3: 271–290

    Article  PubMed  CAS  Google Scholar 

  27. Neill JD (1980) Neuroendocrine regulation of prolactin secretion. Raven, New York, pp 129–155 (Frontiers in neuroendocrinology, vol 6 )

    Google Scholar 

  28. Pohl CR, Knobil E (1982) The role of the central nervous system in the control of ovarian function in higher primates. Annu Rev Physiol 44:583–593

    Google Scholar 

  29. Raue F, Ziegler R (1986) Pathophysiologie der Nervenschilddrüsen and der Kalziumhomöostase. Endokrinologie der Kindheit und Adoleszenz. Thieme, Stuttgart

    Google Scholar 

  30. Rechler MM, Missley SP (1985) The nature and regulation of the receptors for insulin-like growth factors. Annu Rev Physiol 47:425–442

    Google Scholar 

  31. Reiter RJ (1982) Neuroendocrine effects of the pineal gland and of melatonin. Raven, New York, pp 287–316 (Frontiers in neuroendocrinology, vol 7 )

    Google Scholar 

  32. Reiter E0, Grumbach MM (1982) Neuroendocrine control mechanisms and the onset of puberty. Annu Rev Physiol 44:595–613

    Google Scholar 

  33. Schally AV (1978) Aspects of hypothalamic regulation of the pituitary gland (Nobel lecture). Science 202: 18–28

    Article  PubMed  CAS  Google Scholar 

  34. Seran-Ferré M, Jaffe RB (1981) The fetal adrenal gland. Annu Rev Physiol 43x41–162

    Google Scholar 

  35. Siiteri PK, Murai JT, Hammond GL, Nisker JA, Raymoure WJ, Kuhn RW (1982) The serum transport of steroid hormones. Recent Prog Horm Res 38: 457–510

    PubMed  CAS  Google Scholar 

  36. Straus DS (1984) Growth-stimulatory actions of insulin in vitro and in vivo. Endocr Rev 5 /2: 356–369

    Article  PubMed  CAS  Google Scholar 

  37. Verney EB (1947) The antidiuretic hormone and the fac- tor which affect its release. Proc R Soc Lond 135: 25–106

    Article  PubMed  CAS  Google Scholar 

  38. Wakerley JB, Lincoln DW (1973) The milk-ejection reflex in the rat. A zo-to 4o-fold acceleration in the firing of paraventricular neurons during oxytocin release. J Endocr 57:477–493

    Google Scholar 

  39. Wuttke W, Jarry H, Knoke I, Spiess S (1993) Luteotrophic and luteolytic actions of ovarian peptides. Hum Reprod 8: 141–146

    Article  PubMed  CAS  Google Scholar 

  40. Wuttke W, Jarry H, Einspanier A, Pitzel L, Holtz W, Die- trich E (1990) In vivo and in vitro effects of ovarian regulatory peptides on follicullar and luteal progesterone release. In: Genazzani AR, Nappi G, Petraglia F, Martignoni E (eds) Stress and related disorders from adaptation to dysfunction. Parthenon Publishing Group, Park Ridge, New Jersey, pp 311–319

    Google Scholar 

  41. Wuttke W, Jarry H, Pitzel L, Dietrich E, Spiess S (1992) Luteotropic and luteolytic effects of peptides in the porcine and human corpus luteum. In: Hsueh AJW, Schomberg DW (eds) Ovarian cell interactions. Genes to physiology. Springer, Berlin Heidelberg New York, pp 167–180

    Google Scholar 

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Authors
  1. W. Wuttke
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Editors and Affiliations

  1. Physiologisches Institut, Universität Würzburg, Röntgenring 9, D-97070, Würzburg, Deutschland

    Robert F. Schmidt

  2. Institut für Physiologie und Pathophysiologie, Universität Mainz, Saarstraße 21, D-55122, Mainz, Deutschland

    Gerhard Thews

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© 1995 Springer-Verlag Berlin Heidelberg

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Wuttke, W. (1995). Endokrinologie. In: Schmidt, R.F., Thews, G. (eds) Physiologie des Menschen. Springer-Lehrbuch. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-09334-4_20

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  • DOI: https://doi.org/10.1007/978-3-662-09334-4_20

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-09335-1

  • Online ISBN: 978-3-662-09334-4

  • eBook Packages: Springer Book Archive

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