Zusammenfassung
Die Entwicklung empfindlicher Elektronen-Auffangmethoden der Gaschromatographie zur Messung der Konzentrationen von Isosorbiddinitrat (ISDN) im Plasma [4, 5, 7, 10] hat das Studium der Pharmakokinetik dieser Substanz erleichtert. Die Plasmakonzentrationen, die nach oralen und sublingualen Dosen von Standard- und Retard-Präparaten sowie nach lokaler Applikation von Salben erzielt werden, sind heute ausreichend belegt [1, 2, 8, 12] .
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Literatur
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© 1982 Springer-Verlag Berlin Heidelberg
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Taylor, T., Chasseaud, L.F. (1982). Pharmakokinetik von Isosorbiddinitrat beim Menschen. In: Engel, H.J., Schrey, A., Lichtlen, P.R. (eds) Nitrate III. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08981-1_5
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DOI: https://doi.org/10.1007/978-3-662-08981-1_5
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