Hyperprolactinaemia: Results of Operation in Patients Selected on the Basis of Dynamic Endocrine Tests
In 1979 we suggested that dynamic endocrine tests would be useful in the detection of small prolactinomas, irrespective of radiological findings (1). Among our reasons for this approach were, first, the uncertainty about the significance of minor changes in the radiological appearances of the pituitary fossa, and second, the hope that optimum results would be obtained by an operation performed before a tumour had become large enough to produce a markedly abnormal fossa. Forty women thought to have an intrasellar prolactinoma, on the basis of abnormal prolactin dynamics, have now undergone trans-sphenoidal operation. We report the findings at operation and their relationship to the preoperative endocrine and radiological studies, and results of this method of management.
KeywordsPituitary Adenoma Cavernous Sinus Serum Prolactin Pituitary Fossa Anterior Pituitary Function
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