Abstract
Sweet broomweed (Scoparia dulcis L., Scrophulariaceae) is a perennial herb widely distributed in the torrid zone. The original habitat of this plant is tropical America. Stems are erect, branching, and sometimes woody at the base, 25–80 cm tall. (Fig. 1) Roots are pale yellow and straight, 10–15 cm long, with many lateral roots. Leaves are lanceolate, elliptical, or obovate, 5–20 mm long, with serrations at the edge, and are opposite or verticillate. The plant has small, white flowers with four calices. The corrola is actinomorphic and split in four. Flowers are 4–5 mm in diameter and bear four stamens and a pistil. Flowering time is summer and autumn. After flowering, ovate or globular capsules mature (2–3 mm in diameter), which contain many powder-like seeds.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Asano S, Mizutani M, Hayashi T, Morita N, Takeguchi N (1990) Reversible inhibitions of gastric H *, K *-ATPase by scopadulcic acid B and acetyl scopadol. New biological tools of H *, K *-ATPase. J Biol Chem 265: 22167–22173
Chen C, Chen M (1976) 6-methoxybenzoxazolinone and triterpenoids from roots of Scoparia dulcis. Phytochemistry 15: 1997–1999
Chiang Su New Medical College (1977) Dictionary of Chinese Materia Medica (Zhong Yao Da Ci Dian), Jiangsu New Medical College, Shanghai Scientific and Technological Publisher, Shanghai. 2132 pp
Chow SY, Chen SM, Yang CM, Hsu H (1974) Pharmacological studies on Chinese herbs (1) Hypotensive effect of 30 Chinese herbs. J Formosan Med Assoc 73: 729–739
Farias Freie SM, Silva Emin JA, Lapa AJ, Souccar C, Brandao Torres LM (1993) Analgesic and antiinflammatory properties of Scoparia dulcis L. extract and glutinol in rodents. Phytother Res 7: 408–414
Gonzales Torres DM (1986) Catalogo de plantas medicinales (y Alimenticias y Utiles) Usada en Paraguay, Asuncion, Paraguay, 394 pp
Hayashi K, Niwayama S, Hayashi T, Nago R, Ochiai H, Morita N (1988) In vitro and in vivo antiviral activity of scopadulcic acid B from Scoparia dulcis, Scrophulariaceae, against herpes simplex virus type 1. Antiviral Res 9: 345–354
Hayashi K, Hayashi T, Morita N (1992) Cytotoxic and antitumour activity of scopadulcic acid B from Scoparia dulcis L. Phytother Res 6: 6–9
Hayashi K, Hayashi T, Arisawa M, Morita N (1993) Antiviral agents of plant origin. Antiherpetic activity of acacetin. Antiviral Chem Chemother 4: 49–53
Hayashi T, Kishi M, Kawasaki M, Arisawa M, Morita N (1988) The crystal structure of scopadulcic acid A from the Paraguayan crude drug Typycha kuratu (Scoparia dulcis L.). J Nat Prod 51: 360–363
Hayashi T, Uchida K, Hayashi K, Niwayama S, Morita N (1988b) A cytotoxic flavone from Scoparia dulcis L. Chem Pharm Bull 36: 4849–4851
Hayashi T, Okamura K, Kakemi M, Asano S, Mizutani M, Takeguchi N, Kawasaki M, Tezuka Y, Kikuchi T, Morita N (1990a) Scopadulcic acid B, a new tetracyclic diterpenoid from Scoparia dulcis L. Its structure, H *,k *-adenosine triphosphatase inhibitory activity and pharmacokinetic behaviour in rats. Chem Pharm Bull 38: 2740–2745
Hayashi T, Kawasaki M, Miwa Y, Taga T, Morita N (1990b) Antiviral agents of plant origin III. Scopadulin, a novel tetracyclic diterpene from Scoparia dulcis L. Chem Pharm Bull 38: 945–947
Hayashi T, Asano S, Mizutani M, Takeguchi N, Kojima T, Okamura K, Morita N (1991a) Scopadulciol, an inhibitor of gastric H*,K*-ATPase from Scoparia dulcis and its structure-activity relationships. J Nat Prod 54: 802–809
Hayashi T, Okamura K, Kawasaki M, Morita N (1991b) Two chemotypes of Scoparia dulcis in Paraguay. Phytochemistry 30: 3617–3620
Hayashi T, Kawasaki M, Okamura K, Tamada Y, Morita N, Tezuka Y, Kikuchi T, Miwa Y, Taga T (1993a) Scoparic acid A, a ß-glucuronidase inhibitor from Scoparia dulcis. J Nat Prod 55: 1748–1755
Hayashi T, Okamura K, Tamada Y, lida A, Fujita T, Morita N (19936) A new chemotype of Scoparia dulcis. Phytochemistry 32: 349–352
Hayashi T, Okamura K, Kawasaki M, Morita N (1993c) Production of diterpenoids by cultured cells from two chemotypes of Scoparia dulcis. Phytochemistry 33: 353–356
Hayashi T, Gotoh K, Ohnishi K, Okamura K, Asamizu T (1994) Content of 6-methoxy-2-benzoxazolinone (MBOA) in Scoparia dulcis and its production by cultured tissues. Phytochemistry 37: 1611–1614
Kawasaki M, Hayashi T, Arisawa M, Morita N, Berganza LH (1988) 8-Hydroxytricetin-7- glucuronide, a ß-glucuronidase inhibitor from Scoparia dulcis. Phytochemistry 27: 3709–3711
Murashige T, Skoog T (1962) A revised medium for rapid growth and bioassays with tobacco tissue cultures. Physiol Plant 15: 473–497
Nath MC (1943) Investigations on the new antidiabetic principle (amellin) occurring in nature Part I. Studies on some of its biochemical properties. Ann Biochem Exp Med 3: 55–62
Nishino H, Hayashi T, Arisawa M, Satomi Y, Iwashima A (1993) Antitumor-promoting activity of scopadulcic acid B from medicinal plant Scoparia dulcis L. Oncology 50: 100–103
Otsuka H, Hirai Y, Nagao T, Yamazaki K (1988) Anti-inflammatory activity of benzoxazolinoids from roots of Coix lachryma jobi var. Ma-yuen. J Nat Prod 51: 74–79
Overman LE, Ricca DJ, Tran VD (1993) First total synthesis of scopadulcic acid B. J Am Chem Soc 115: 2042–2044
Perry LM (1980) Medicinal plants of East and Southeast Asia: attributed properties and uses. The MIT Press, Cambridge, MA, 385 pp
Satyanarayana K (1969) Chemical examination of Scoparia dulcis (Linn): Part I. J Indian Chem Soc 46: 765–766
Yamazaki M, Son L, Hayashi T, Morita N, Asamizu T, Murakoshi T, Saito K (1996) Transgenic fertile Scoparia dulcis L., a folk medicinal plant, conferred with a herbicide-resistant trait using an Ri binary vector. Plant Cell Rep 15: 317–321
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1996 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Hayashi, T. (1996). Scoparia dulcis L. (Sweet Broomweed): In Vitro Culture and the Production of Diterpenoids and Other Secondary Metabolites. In: Bajaj, Y.P.S. (eds) Medicinal and Aromatic Plants IX. Biotechnology in Agriculture and Forestry, vol 37. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08618-6_22
Download citation
DOI: https://doi.org/10.1007/978-3-662-08618-6_22
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-08229-0
Online ISBN: 978-3-662-08618-6
eBook Packages: Springer Book Archive