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Management des MAMMAKARZINOMS pp 227–253Cite as

Adjuvante systemische Therapie

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Part of the book series: Onkologie ((ONKAKTUELL))

Zusammenfassung

Eine größere Anzahl von einzelnen Studien, insbesondere aber die Metaanalyse der „Early Breast Cancer Trialist’s Collaborative Group“ (EB-CTCG), haben den Nutzen einer Chemo- und Hormontherapie in der adjuvanten Behandlung des Mammakarzinomes eindrucksvoll bewiesen. Die letzte publizierte Metaanalyse datiert aus dem Jahre 1998 (Early Breast Cancer Trialists’ Collaborative Group 1998a, b). Ihre Ergebnisse haben einen Paradigmenwechsel in der Therapie eingeleitet. Während bis dato das Alter der Patientin (Prä- vs. Postmenopause) die Hauptdiskriminante der Therapieentscheidung war (Chemo- vs. Hormontherapie), ist diese durch den Nachweis der Expression des Steroidrezeptors ersetzt worden.

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  1. V. Möbus
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  1. Universitätsfrauenklinik, Universität Ulm, Prittwitzstraße 43, D-89075, Ulm, Deutschland

    Rolf Kreienberg  & Tanja Volm  & 

  2. Städt. Kliniken Frankfurt-Höchst Akademisches Lehrkrankenhaus, Universität Frankfurt, Frauenklinik, Gotenstraße 6-8, D-65929, Frankfurt, Deutschland

    Volker Möbus

  3. Untere Kippstraße 21, D-69198, Schriesheim, Deutschland

    Dieter Alt

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© 2002 Springer-Verlag Berlin Heidelberg

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Möbus, V., Volm, T., Kreienberg, R. (2002). Adjuvante systemische Therapie. In: Kreienberg, R., Volm, T., Möbus, V., Alt, D. (eds) Management des MAMMAKARZINOMS. Onkologie Aktuell . Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08460-1_16

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  • DOI: https://doi.org/10.1007/978-3-662-08460-1_16

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-08461-8

  • Online ISBN: 978-3-662-08460-1

  • eBook Packages: Springer Book Archive

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