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Lantibiotics and Related Peptides pp 41–83Cite as

Chemistry and Structure

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Part of the book series: Biotechnology intelligence unit ((BIOIU))

Abstract

While the existence of nisin had been identified as early as 19281 and subtilin was discovered in 1944,2 it was several decades before researchers were able to gain some clues as to the nature of the inhibitory activity which they were observing. It had often been hypothesized that nisin, subtilin and similar inhibitory activities could be used in the then relatively new field of antibiosis as chemotherapeutics; for example, studies were performed suggesting that nisin might have efficacy in the treatment of veterinary diseases such as mastitis in dairy herds.3–6

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Authors and Affiliations

  1. Institute for Organic Chemistry, University of Tübingen, Tübingen, Germany

    Ralph W. Jack Ph.D.

  2. ECHAZ microcollections, Reutlingen, Germany

    Ralph W. Jack Ph.D.

  3. Institute for Medical Microbiology and Immunology, University of Bonn, Bonn, Germany

    Gabriele Bierbaum Ph.D. & Hans-Georg Sahl Ph.D.

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  1. Ralph W. Jack Ph.D.
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  2. Gabriele Bierbaum Ph.D.
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  3. Hans-Georg Sahl Ph.D.
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© 1998 Springer-Verlag Berlin Heidelberg

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Jack, R.W., Bierbaum, G., Sahl, HG. (1998). Chemistry and Structure. In: Lantibiotics and Related Peptides. Biotechnology intelligence unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08239-3_2

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