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Endokrinium und Tumorwachstum

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Zusammenfassung

Zwischen dem Endokrinium einerseits sowie der atypischen Zeilproliferation und dem gut- und bösartigen Tumorwachstum andererseits gibt es eine Reihe funktioneller Beziehungen. Einige Hormone können das Wachstum bestimmter Tumoren fördern oder hemmen. Man nennt letztere hormonabhängige Tumoren. Die Entstehung der nodulären Leberzellhyperplasie und der Lebertumoren unter dem Einfluß ethinylöstradiolhaltiger Medikamente (Kap. 21) und die Häufung der glandulärzystischen Hyperplasie, der adenomatösen Hyperplasie und des Endometriumkarzinoms unter chronischer proliferationsfördernder Einwirkung von Östrogenen, die nicht durch endogene oder exogene Gestagene unterbrochen wird, sind Beispiele hierfür (Kap. 20). Analoges gilt für die Hormonwirkung an der Brust. Auch dort kann eine hormonelle Dysbalance bzw. eine kontinuierliche, nicht durch Progesteron oder exogene Gestagene unterbrochene Östrogenwirkung gut- und bösartige Proliferationsvorgänge fördern, wie unten noch näher auszuführen sein wird.

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© 1992 Springer-Verlag Berlin Heidelberg

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Leidenberger, F.A. (1992). Endokrinium und Tumorwachstum. In: Klinische Endokrinologie für Frauenärzte. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-08110-5_23

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  • DOI: https://doi.org/10.1007/978-3-662-08110-5_23

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