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Endotoxinbindende Proteine

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Intensivtherapie bei Sepsis und Multiorganversagen

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Zusammenfassung

Endotoxine sind integraler Bestandteil der äußeren Membran gramnegativer Bakterien wie Enterobakteriaceae, Neisserien und Chlamydien. Sie sind bei zahlreichen physiologischen Membranfunktionen beteiligt und sind essentiell für das Wachstum von Bakterien und deren Überleben. Endotoxine repräsentieren die hitzestabilen O-Antigene von Bakterien und definieren somit die Vielfalt der unterschiedlichen Serotypen. Schließlich zeigen Endotoxine ein großes Spektrum biologischer Aktivitäten nach der Injektion in Tieren und in In-vitro-Modellen [28].

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Authors
  1. P. Zabel
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  1. Medizinische Klinik I, Städtisches Krankenhaus Hildesheim, Lehrkrankenhaus der Medizinischen Hochschule Hannover, Weinberg 1, 31134, Hildesheim, Deutschland

    Hans-Peter Schuster

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© 1996 Springer-Verlag Berlin Heidelberg

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Zabel, P. (1996). Endotoxinbindende Proteine. In: Schuster, HP. (eds) Intensivtherapie bei Sepsis und Multiorganversagen. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07958-4_5

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  • DOI: https://doi.org/10.1007/978-3-662-07958-4_5

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-07959-1

  • Online ISBN: 978-3-662-07958-4

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