Zusammenfassung
Es kann kein Zweifel bestehen, daß die Antibiotikaresistenz bei Infektionserregern wenngleich kein neues, so doch ein zunehmendes medizinisches und gesundheitliches Problem von globaler Bedeutung darstellt (Abb. 4.4.1, Tabelle 4.4.1).
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Archer, G. L., D. M. Niemeyer (1994) Origin and evolution of DNA associated with resistance to methicillin in staphylococci. Trends Microbiol 2:343–346
Arthur, M., P. Courvalhin (1993) Genetics and mechanisms of glycopeptide resistance in enterococci. Antimicrob Agents Chemother 37:1563–1571
Bossche, H. V., P. Marichal, F. C. Odds (1994) Molecular mechanisms of drug resistance in fungi. Trends Microbiol 2:393–400
Böttger, E. C. (1994) Resistance to drugs targeting protein synthesis in mycobacteria. Trends Microbiol 2:416–421
Böttger, E. C., B. Springer, M. Pletschette, P. Sander (1998) Fitness of antibiotic-resistant microorganisms and compensatory mutations. Nature Med; in press
Cohen, M. L. (1992) Epidemiology of drug resistance: implications for a post-antimicrobial era. Science 257:1050–1055
Cole, S. T. (1994) Mycobacterium tuberculosis: drug-resistance mechanisms. Trends Microbiol 2:411–415
Condra, J. H., E. A. Emini. (1997) Preventing HIV-1 drug resistance. SciMed 4:2–11
Courvalhin, P. (1992) Interpretative reading of antimicrobial susceptibility tests. ASM News 58:368–375
Courvalhin, P. (1994) Transfer of antibiotic resistance genes between gram-positive and gram-negative bacteria. Antimicrob Agents Chemother 38:1447–1451
Davies, J. (1994) Inactivation of antibiotics and the dissemination of resistance genes. Science 264:375–381
Dowson, C. G., T. J. Coffey, B. G. Spratt (1994) Origin and molecular epidemiology of penicillin-binding protein-mediated resistance to β-lactam antibiotics. Trends Microbiol 2:361–365
Georgopapadakov, N. H. (1993) Penicillin-binding proteins and bacterial resistance to β-lactams. Antimicrob Agents Chemother 37:2045–2053
Huovinen, P., L. Sundström, G. Swedberg, O. Skold (1995) Trimethoprim and sulfonamide resistance. Antimicrob Agents Chemother 39:279–289
Inderlied, C. B., K. A. Nash (1996) Antimycobacterial agents: in vitro susceptibility testing, spectra of activity, mechanisms of action and resistance, and assays for activity in biological fluids. In: V. Lorian (ed) Antibiotics in laboratory medicine. Williams & Wilkins, Baltimore, pp 127–176
Jacoby, G. A. (1994) Extrachromosomal resistance in gram-negative organisms: the evolution of β-lactamases. Trends Microbiol 2:357–360
McGinnis, M. R., M. G. Rinaldi (1996) Antifugal drugs: mechanisms of action, drug resistance, susceptibility testing and assays of activity in biological fluids. In: V. Lorian (ed) Antibiotics in laboratory medicine. Williams & Wilkins, Baltimore, pp 176–212
Meier, A., L. Heifets, R. J. Wallace, Y. Zhang, B. A. Brown, P. Sander, E. C. Böttger (1996) Molecular mechanism of clarithromycin resistance in Mycobacterium avium observation of multiple 23S rRNA mutations in a clonal population. J Infect Dis 174:354–360
Neu, H. C. (1994) The crisis in antibiotic resistance. Science 257:1064–1073
Nikaido, H. (1994) Prevention of drug access to bacterial targets: permeability barriers and active efflux. Science 264:382–387
Rice, L. B., R. A. Bonomo (1996) Genetic and biochemical mechanisms of bacterial resistance to antimicrobial agents. In: V. Lorian (ed) Antibiotics in laboratory medicine. Williams & Wilkins, Baltimore, pp 453–501
Richman, D. D. (1994) Drug resistance in viruses. Trends Microbiol 2:401–406
Roberts, M. C. (1994) Epidemiology of tetracycline-resistance determinants. Trends Microbiol 2:353–356
Sander, P., A. Meier, E. C. Böttger (1996) Ribosomal drug resistance in mycobacteria. Res Microbiol 147:59–67
Sander, P., T. Prammananan, E. C. Böttger (1996) Introducing mutations into a chromosomal rRNA gene using a genetically modified eubacterial host with a single rRNA Operon. Mol Microbiol 22:841–848
Sander, P., T. Prammananan, A. Meier, K. Frischkorn, E. C. Böttger (1997) The role of ribosomal RNA in macrolide resistance. Mol. Microbiol. 26:469–480
Spratt, B. G. (1994) Resistance to antibiotics mediated by target alterations. Science 264:389–393
Spratt, B. G. (1996) Antibiotic resistance: counting the cost. Curr Biol 6:1219–1221
Taylor, D. E., A. Chau (1996) Tetracycline resistance mediated by ribosomal protection. Antimicrob Agents Chemother 40:1–5
Witte, W., I. Klare (1995) Glycopeptide-resistant Enterococcus faecium outside hospitals: a commentary. Microbial Drug Res 1:259–263
Woodford, N., A. P. Johnson, D. Morrison, D. C. E. Speller (1995) Current perspectives on glycopeptide resistance. Clin Microbiol Rev 8:585–615
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Böttger, E.C., Kern, P. (1999). Molekulare Mechanismen und klinische Aspekte der Resistenz. In: Ganten, D., Ruckpaul, K. (eds) Immunsystem und Infektiologie. Handbuch der Molekularen Medizin, vol 4. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07865-5_13
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DOI: https://doi.org/10.1007/978-3-662-07865-5_13
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