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Kutane T-Zell-Lymphome

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Histopathologie der Haut

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Zusammenfassung

Kutane T-Zell-Lymphome (KTZL, „cutaneous T-cell lymphomas“/CTCL) sind eine heterogene Gruppe kutaner Neoplasien. Primäre KTZL sind definitionsgemäß Proliferationen klonaler T-Lymphozyten, welche sich primär in der Haut manifestieren. Die Inzidenz kutaner Lymphome beträgt 5–10 Fälle pro einer Million Einwohner pro Jahr, wobei die primären KTZL die Mehrheit (65%) der primären kutanen Lymphome ausmachen. Im Gegensatz zu den primären kutanen B-Zell-Lymphomen (KBZL, „cutaneous B-cell lymphomas“/CBCL) manifestieren sich KTZL klinisch und histologisch unter mannigfaltigen Bildern, welche zudem in den Anfangsstadien nicht selten gutartige Dermatosen wie Ekzeme und Psoriasis imitieren. Der histologischen Beurteilung kommt eine zentrale Bedeutung in der Diagnostik der primären KTZL zu.

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Authors
  1. W. Kempf
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  2. R. Dummer
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  3. G. Burg
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Editors and Affiliations

  1. Universitätsklinik für Dermatologie und Venerologie, Karl-Franzens-Universität Graz, Auenbruggerplatz 8, A-8036, Graz, Österreich

    Helmut Kerl  & Lorenzo Cerroni  & 

  2. Universitäts-Hautklinik, Eberhard-Karls-Universität Tübingen, Liebermeisterstraße 25, D-72076, Tübingen, Deutschland

    Claus Garbe

  3. Klinik für Dermatologie und Venerologie, Universität zu Lübeck, Ratzeburger Allee 160, D-23562, Lübeck, Deutschland

    Helmut H. Wolff

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Kempf, W., Dummer, R., Burg, G. (2003). Kutane T-Zell-Lymphome. In: Kerl, H., Garbe, C., Cerroni, L., Wolff, H.H. (eds) Histopathologie der Haut. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07784-9_38

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  • DOI: https://doi.org/10.1007/978-3-662-07784-9_38

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-07785-6

  • Online ISBN: 978-3-662-07784-9

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