Zusammenfassung
Eine Revolution ist im Gang, eine Revolution auf dem Gebiet der Medizin. Neue Erkenntnisse in der Molekularen Genetik und speziell die Entwicklungen in der Genomforschung führen zu bisher nicht da gewesenen Fertigkeiten und Perspektiven. Dabei finden diese rasanten Veränderungen parallel auf 3 Ebenen statt:
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1.
Der hohe Erkenntnisgewinn aus den Untersuchungen und methodischen Entwicklungen der Genomanalyse vergrößert das grundlegende, das molekulare Verständnis biologischer Vorgänge und ihres Nachweises und führt damit zu direkten Verbesserungen in medizinischen Anwendungen.
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2.
Als Ergebnis der Gentechnologie werden neue Methoden zur Verfügung stehen, die umwälzende Behandlungsformen ermöglichen.
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3.
Zumindest ein Teil der biomedizinischen Forschung wandelt sich weg von der Untersuchung von Einzelaspekten in einem relativ kleinen Rahmen und hin zu breit angelegten Projekten zur Analyse gesamtzellulärer Zusammenhänge, ein Vorgang der auch ein Umdenken der betroffenen Wissenschaftler erfordert.
Die resultierende Kenntnis komplexer Zusammenhänge hat wiederum unmittelbare Auswirkungen auf das Verständnis von Krankheiten und den Wegen zu ihrer Behandlung. Dieser Wandel im wissenschaftlichen Arbeiten und der Forschungskonzeption begann mit der Genomforschung und setzt sich mittlerweile in der Projektierung und Abwicklung derjenigen Studien fort, die sich daran anschließen.
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Würtz, S., Hanke, J., Solinas-Toldo, S., Hoheisel, J.D. (2003). Genomanalyse und Gendiagnostik. In: Ganten, D., Ruckpaul, K. (eds) Grundlagen der Molekularen Medizin. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07588-3_13
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