Abstract
Recurrent aphthous stomatitis (RAS) or recurrent aphthous ulcers (RAU) are painful oral ulcerations that characteristically recur at intervals ranging from days to months or even years. They represent the most common lesion of the oral mucosa with an overall prevalence; ranging from 15 to 30%. Females are more commonly affected than males and although they may begin at any age, they usually start during the second and third decades of life. Familial occurrence is common and about 30–40% of the patients with RAS have another affected family member.
This is a preview of subscription content, log in via an institution to check access.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
Further reading
Ball SC, Sepkowitz KA, Jacobs JL. Thalidomide for treatment of oral aphthous ulcers in patients with human immunodeficiency virus: case report and review. Am J Gastroenterol 1997; 92: 169–70.
Brown RS, Bottomley WK. Combination immunosuppressant and topical steroid therapy for treatment of recurrent major aphthae Oral Surg Oral Med Oral Pathol 1990; 69: 42–4
Haeyrinen-Immonen R, Sorsa T, Pettilae J et al. Effect of tetracycline on collagenase activity in patients with recurrent aphthous ulcers J Oral Pathol Med 1994; 23: 269–72
Laskaris G Color Atlas of Oral Diseases2nd edn. Stuttgart: Thieme, 1994: 177–8
Laskaris G. Advances in the classification and treatment of recurrent aphthous ulcers Balk J Stomatol 1999; 3: 83–4
Paterson DL, Georghiou PR, Allworth AM, Kemp RJ. Thalidomide as treatment of refractory aphthous ulceration related to human immunodeficiency virus infection Clin Infect Dis 1995; 20: 250–4
Porter SR, Scully C. Aphthous stomatitis—an overview of aetiopathogenesis and management Clin Exp Dermatol 1991; 16: 235–43
Rees TD, Binnie WH. Recurrent aphthous stoma-titis Dermatol Clin 1996; 14: 243–56
Vincent SD, Lilly GE. Clinical, historic and therapeutic features of aphthous stomatitis Oral Surg Oral Med Oral Pathol 1992; 74: 79–86
Woo SB, Sonis ST. Recurrent aphthous ulcers. a review of diagnosis and treatment J Am Dermatol Acad 1996; 127: 1202–13
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 2003 Springer-Verlag Berlin Heidelberg
About this chapter
Cite this chapter
Laskaris, G. (2003). Aphthous stomatitis. In: Katsambas, A.D., Lotti, T.M. (eds) European Handbook of Dermatological Treatments. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-07131-1_7
Download citation
DOI: https://doi.org/10.1007/978-3-662-07131-1_7
Publisher Name: Springer, Berlin, Heidelberg
Print ISBN: 978-3-642-05657-4
Online ISBN: 978-3-662-07131-1
eBook Packages: Springer Book Archive