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Gallenblasen- und Gallengangskarzinom

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Zusammenfassung

Die Karzinome der Gallenblase und der extrahepatischen Gallenwege zählen mit 0,5–1% aller Neoplasien zu den seltenen malignen Erkrankungen. Aufgrund der unspezifischen Symptomatik und der Tatsache, dass potentiell kurable Tumoren mithilfe bildgebender Verfahren oft nicht dargestellt werden können, sowie fehlender effektiver systemischer Therapiemodalitäten, beträgt die Fünfjahresüberlebensrateetwa 5%. Die Inzidenz der Gallenblasen-/Gallengangskarzinome entspricht daher ungefähr der Mortalitätsrate. Jährlich erkranken weltweit etwa 2–3/100.000 an einem Karzinom der Gallenblase/-wege. Gehäuftes Auftreten wird in Israel mit einer Inzidenz von 13/100.000 pro Jahr sowie in Mexiko, Bolivien und Chile beobachtet. Die Wahrscheinlichkeit an einem Karzinom der Gallenblase/-gänge zu erkranken ist bis zum 4. Lebensjahrzehnt eher gering und steigt ab dem 6. Lebensjahrzehnt deutlich an, wobei der Altersgipfel zwischen dem 5. und 7. Lebensjahrzehnt liegt. Das Gallenblasenkarzinom wird häufiger bei Frauen diagnostiziert (Geschlechtsverhältnis 3:1), während das Gallengangskarzinom eher beim Mann auftritt (Geschlechtsverhältnis 2:1).

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Kornek, G. (2004). Gallenblasen- und Gallengangskarzinom. In: Die Onkologie. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06670-6_41

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  • DOI: https://doi.org/10.1007/978-3-662-06670-6_41

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-06671-3

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