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Basic Characteristics and Ion Binding to Calreticulin

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Calreticulin

Part of the book series: Molecular Biology Intelligence Unit ((MBIU))

Abstract

Calreticulin is a protein that binds several different cations. In particular, this protein has been shown to have two distinct Ca2+ binding sites: a high capacity, low affinity site and a high affinity, low capacity site.1,2 Because of its high capacity for Ca2+ binding (>20 moles of Ca2+/mole of protein), it has been proposed that calreticulin may be a Ca2+ storage protein.3 This possibility is reviewed, in detail, in Chapter 5. However, in addition to this potential role in Ca2+ storage, several other diverse functions have been proposed for calreticulin (see other chapters in this book).4

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Authors
  1. Shairaz Baksh
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  2. Marek Michalak
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© 1996 Springer-Verlag Berlin Heidelberg

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Baksh, S., Michalak, M. (1996). Basic Characteristics and Ion Binding to Calreticulin. In: Calreticulin. Molecular Biology Intelligence Unit. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06203-6_2

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  • DOI: https://doi.org/10.1007/978-3-662-06203-6_2

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-06205-0

  • Online ISBN: 978-3-662-06203-6

  • eBook Packages: Springer Book Archive

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