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Biological Rhythms pp 164–180Cite as

Neurochemical Aspects of the Entrainment of the Mammalian Suprachiasmatic Circadian Pacemaker

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Abstract

The localisation of the mammalian circadian pacemaker to the suprachiasmatic nucleus of the hypothalamus (SCN) some 27 years ago has lead to an explosion of interest in this area of the brain. Today, research is aimed at determining how zeitgeber information is relayed to the SCN circadian pacemaker, including the identification of the neural pathways via which this information is communicated, the neurochemicals contained in these pathways, the receptors mediating the actions of these neurochemicals, second messenger factors implicated in mediating the phase-resetting effects of neurochemicals, and finally the sequence of intracellular events that lead to changes in clock gene expression.

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Authors and Affiliations

  1. School of Biological Sciences, University of Manchester, 3.614 Stopford Building, Oxford Road, Manchester, UK, M13 9PT

    H. D. Piggins, A. N. Coogan, D. J. Cutler & H. E. Reed

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  1. H. D. Piggins
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  2. A. N. Coogan
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  3. D. J. Cutler
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  4. H. E. Reed
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Editors and Affiliations

  1. Department of Zoology, University of Lucknow, 226 007, Lucknow, India

    Vinod Kumar (Professor) (Professor)

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© 2002 Springer-Verlag Berlin Heidelberg

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Piggins, H.D., Coogan, A.N., Cutler, D.J., Reed, H.E. (2002). Neurochemical Aspects of the Entrainment of the Mammalian Suprachiasmatic Circadian Pacemaker. In: Kumar, V. (eds) Biological Rhythms. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-06085-8_14

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  • DOI: https://doi.org/10.1007/978-3-662-06085-8_14

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