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Fluoreszenzangiographie bei altersabhängiger Makuladegeneration

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Zusammenfassung

Obwohl der Verdacht auf das Vorliegen einer altersabhängigen Makuladegeneration zunächst anhand von Anamnese und funduskopischer Untersuchung des Patienten erhoben werden kann, stellt die Fluoreszenzangiographie das derzeit wichtigste Instrument für eine präzise Diagnosestellung, nähere Charakterisierung und das Monitoring von Therapieeffekten dar. Zwei Fluoreszenzfarbstoffe kommen hierfür in der Augenheilkunde zur Anwendung: Fluoreszein, welches hauptsächlich für die retinale Angiographie verwendet wird, und Indozyaningrün, das in der choroidalen Angiographie zum Einsatz kommt (Spaide 1999; Tittl et al. 1999). Die Fluoreszeinangiographie wurde viel früher entwickelt, und so liegen weiterreichende Erfahrungen hinsichtlich der Korrelation zwischen fluoreszeinangiographischen Befunden und Histopathologie vor.Anwendung und Aussagekraft der Indozyaningrün-(ICG-)Angiographie sind mit der technologischen Entwicklung der bildgebenden Systeme seit einigen Jahren verbessert worden, allerdings bestehen noch Unklarheiten hinsichtlich der Relevanz der gewonnenen Befunde. Dennoch hat die Indozyaningrün-Angiographie vielfältige neue Einsichten in die Pathophysiologie verschiedener Typen choroidaler Neovaskularisationen ermöglicht.

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© 2004 Springer-Verlag Berlin Heidelberg

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Spaide, R.F., Eter, N. (2004). Fluoreszenzangiographie bei altersabhängiger Makuladegeneration. In: Altersabhängige Makuladegeneration. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05681-3_6

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  • DOI: https://doi.org/10.1007/978-3-662-05681-3_6

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-662-05682-0

  • Online ISBN: 978-3-662-05681-3

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