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Nuclear Perturbations Following Adenovirus Infection

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Adenoviruses: Model and Vectors in Virus-Host Interactions

Part of the book series: Current Topics in Microbiology and Immunology ((CT MICROBIOLOGY,volume 272))

Abstract

Adenoviruses are processed and assembled in the nuclei of infected cells and thereby produce significant perturbations to their structure and function. As the complex interactions that occur in the nuclei of uninfected cells are not yet fully understood many of the changes seen on infection have been described mainly in morphological terms. This chapter attempts to place more recent findings into this context and demonstrates that adenoviruses are able to hijack many cellular processes and enzymes to their advantage. In particular, modifications to nuclear PODs and nucleoli have more recently been explored in greater detail.

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Author information

Authors and Affiliations

  1. University of St Andrews, Fife, BMS Building, KY16 9ST, Fife, Scotland, UK

    W. C. Russell

  2. Department of Pathology and Microbiology, School of Medical Sciences, University Walk, Bristol University, Bristol, BS8 ITD, UK

    D. A. Matthews

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  1. W. C. Russell
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  2. D. A. Matthews
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Editors and Affiliations

  1. Institut für Klinische und Molekulare Virologie, Universität Erlangen-Nürnberg, 91054, Erlangen, Germany

    Walter Doerfler

  2. Institut für Genetik, Universität zu Köln, Weyertal 121, 50931, Köln, Germany

    Petra Böhm

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© 2003 Springer-Verlag Berlin Heidelberg

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Russell, W.C., Matthews, D.A. (2003). Nuclear Perturbations Following Adenovirus Infection. In: Doerfler, W., Böhm, P. (eds) Adenoviruses: Model and Vectors in Virus-Host Interactions. Current Topics in Microbiology and Immunology, vol 272. Springer, Berlin, Heidelberg. https://doi.org/10.1007/978-3-662-05597-7_13

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  • DOI: https://doi.org/10.1007/978-3-662-05597-7_13

  • Publisher Name: Springer, Berlin, Heidelberg

  • Print ISBN: 978-3-642-05517-1

  • Online ISBN: 978-3-662-05597-7

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